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The map label for this gene is crt [H]

Identifier: 85374833

GI number: 85374833

Start: 2034658

End: 2035722

Strand: Direct

Name: crt [H]

Synonym: ELI_10030

Alternate gene names: 85374833

Gene position: 2034658-2035722 (Clockwise)

Preceding gene: 85374832

Following gene: 85374834

Centisome position: 66.66

GC content: 64.13

Gene sequence:

>1065_bases
GTGAGCGAAATGACCGACCAAGTCCTGATCCACAAACACGGCCGCGTCGGCCATATCTCGCTCAACCGGCCGAAGGCACT
CCACGCGCTGACGCTAGAGATGTGTCATGCGATGAGCGCGGCGCTGGCCGATTGGGCGGATGACGACGAGGTCGAAGCCA
TCATCCTTGACCACGCCGAGGGCCGTGGTTTCTGCGCCGGCGGCGATATCGCTTTCCTGCGCAATTCGGCTCTGAACGAT
GGCGGCGTGTCGGGCCGGAAGTTCTTCCACGACGAATACCAACTCAACCACCAGATGTTCACCTACGGCAAACCGATCGT
GGCGTTCATGGACGGCATCACCATGGGCGGCGGCGTGGGCATTGCCCTGCCCGCCAAGTTTCGCGTCGCGACCGAGAACA
CCCGCTTCGCCATGCCGGAAACGGGCATCGGGCTGTTCCCCGATGTCGGCGGTGGCTGGCACCTGTCGCGCCTGGGCGGT
CGGCTCGGCCAGTTCCTCGCGCTGACTGGCGCGCGGCTCGACGGAGCGGAGTGCTTGTGGGCGGGCATCGCCACGCATTA
CGTACCGAGCGAGATGCTCGCCGAACTGAAAGCGCGCATCATCGAGAAGCCCGATCGCATTGCGGGTATTCTGTCCGAAC
CGGTGGGCACCCCGCCCAAGGCGCGGATCGAAGGCAATGCCGACAAGATCGCCAAGCACTTCGCCAGCGACCGCTACGAG
GATATCCTCGCCAGCCTCGAAGCGGTGATGGACGAAGACGAATGGGCGGCAAAAGAGCGCGACACGCTCGGCACCAAGAG
CCCGCAGACCTGCAAGGTCGCGCTGCGCCAGCTGGCAGAGAGCAAAAGGCTGACCGACTTCGCCGACAACATGCGCATGG
AATATCGCATCGCGTCGCGCGTTATCATCCGGCCCGATTTCGCGGAGGGCGTTCGCGCCGTGATCGTCGACAAGACAGGC
GATCCCAGATGGGACCCGCCGACGCCCGAAGAGGTCACCGAGGAATTGATCGACAGCATCTTCGCGCCTCTGCCAGAGGG
GGAGGAATGGGTGCCGCTGACCTGA

Upstream 100 bases:

>100_bases
CGATCGAGCGGTTCTGGCGTGACCTGCGCGTCCATTCGATCCTCGAAGGCACCAACCAGGTCATGCGCATGATCGTGGGC
CGCGACCTGCTGCGACAGGG

Downstream 100 bases:

>100_bases
TGGTCGTCCCAGCGCAGGCTGGGATCTCTGTCCGCTTGGTCGGACTTTGCTGAGAAAGATCCCGGCCTTCGCTGGGATGA
CGGAGTTGAAATGAGCTACG

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSEMTDQVLIHKHGRVGHISLNRPKALHALTLEMCHAMSAALADWADDDEVEAIILDHAEGRGFCAGGDIAFLRNSALND
GGVSGRKFFHDEYQLNHQMFTYGKPIVAFMDGITMGGGVGIALPAKFRVATENTRFAMPETGIGLFPDVGGGWHLSRLGG
RLGQFLALTGARLDGAECLWAGIATHYVPSEMLAELKARIIEKPDRIAGILSEPVGTPPKARIEGNADKIAKHFASDRYE
DILASLEAVMDEDEWAAKERDTLGTKSPQTCKVALRQLAESKRLTDFADNMRMEYRIASRVIIRPDFAEGVRAVIVDKTG
DPRWDPPTPEEVTEELIDSIFAPLPEGEEWVPLT

Sequences:

>Translated_354_residues
MSEMTDQVLIHKHGRVGHISLNRPKALHALTLEMCHAMSAALADWADDDEVEAIILDHAEGRGFCAGGDIAFLRNSALND
GGVSGRKFFHDEYQLNHQMFTYGKPIVAFMDGITMGGGVGIALPAKFRVATENTRFAMPETGIGLFPDVGGGWHLSRLGG
RLGQFLALTGARLDGAECLWAGIATHYVPSEMLAELKARIIEKPDRIAGILSEPVGTPPKARIEGNADKIAKHFASDRYE
DILASLEAVMDEDEWAAKERDTLGTKSPQTCKVALRQLAESKRLTDFADNMRMEYRIASRVIIRPDFAEGVRAVIVDKTG
DPRWDPPTPEEVTEELIDSIFAPLPEGEEWVPLT
>Mature_353_residues
SEMTDQVLIHKHGRVGHISLNRPKALHALTLEMCHAMSAALADWADDDEVEAIILDHAEGRGFCAGGDIAFLRNSALNDG
GVSGRKFFHDEYQLNHQMFTYGKPIVAFMDGITMGGGVGIALPAKFRVATENTRFAMPETGIGLFPDVGGGWHLSRLGGR
LGQFLALTGARLDGAECLWAGIATHYVPSEMLAELKARIIEKPDRIAGILSEPVGTPPKARIEGNADKIAKHFASDRYED
ILASLEAVMDEDEWAAKERDTLGTKSPQTCKVALRQLAESKRLTDFADNMRMEYRIASRVIIRPDFAEGVRAVIVDKTGD
PRWDPPTPEEVTEELIDSIFAPLPEGEEWVPLT

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=357, Percent_Identity=43.1372549019608, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI37594469, Length=312, Percent_Identity=42.9487179487179, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI194097323, Length=193, Percent_Identity=34.1968911917098, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI68989263, Length=214, Percent_Identity=28.5046728971963, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI221142681, Length=186, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787659, Length=206, Percent_Identity=26.6990291262136, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787660, Length=234, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788597, Length=192, Percent_Identity=28.125, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788682, Length=206, Percent_Identity=24.7572815533981, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25144157, Length=352, Percent_Identity=41.1931818181818, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI25144160, Length=352, Percent_Identity=41.1931818181818, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI17554946, Length=207, Percent_Identity=29.4685990338164, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=196, Percent_Identity=30.1020408163265, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=204, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=213, Percent_Identity=27.2300469483568, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=205, Percent_Identity=27.8048780487805, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=370, Percent_Identity=34.3243243243243, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI28571730, Length=350, Percent_Identity=40.5714285714286, Blast_Score=251, Evalue=4e-67,
Organism=Drosophila melanogaster, GI28571729, Length=350, Percent_Identity=40.5714285714286, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI20129971, Length=215, Percent_Identity=29.3023255813954, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24653477, Length=215, Percent_Identity=29.3023255813954, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19922422, Length=190, Percent_Identity=26.8421052631579, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24653139, Length=174, Percent_Identity=27.0114942528736, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 38832; Mature: 38700

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMTDQVLIHKHGRVGHISLNRPKALHALTLEMCHAMSAALADWADDDEVEAIILDHAE
CCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GRGFCAGGDIAFLRNSALNDGGVSGRKFFHDEYQLNHQMFTYGKPIVAFMDGITMGGGVG
CCCEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCE
IALPAKFRVATENTRFAMPETGIGLFPDVGGGWHLSRLGGRLGQFLALTGARLDGAECLW
EEECCEEEEEECCCEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHH
AGIATHYVPSEMLAELKARIIEKPDRIAGILSEPVGTPPKARIEGNADKIAKHFASDRYE
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHH
DILASLEAVMDEDEWAAKERDTLGTKSPQTCKVALRQLAESKRLTDFADNMRMEYRIASR
HHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
VIIRPDFAEGVRAVIVDKTGDPRWDPPTPEEVTEELIDSIFAPLPEGEEWVPLT
EEECCCHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SEMTDQVLIHKHGRVGHISLNRPKALHALTLEMCHAMSAALADWADDDEVEAIILDHAE
CCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GRGFCAGGDIAFLRNSALNDGGVSGRKFFHDEYQLNHQMFTYGKPIVAFMDGITMGGGVG
CCCEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCE
IALPAKFRVATENTRFAMPETGIGLFPDVGGGWHLSRLGGRLGQFLALTGARLDGAECLW
EEECCEEEEEECCCEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHH
AGIATHYVPSEMLAELKARIIEKPDRIAGILSEPVGTPPKARIEGNADKIAKHFASDRYE
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHH
DILASLEAVMDEDEWAAKERDTLGTKSPQTCKVALRQLAESKRLTDFADNMRMEYRIASR
HHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
VIIRPDFAEGVRAVIVDKTGDPRWDPPTPEEVTEELIDSIFAPLPEGEEWVPLT
EEECCCHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]