BacMap

Definition	Erythrobacter litoralis HTCC2594 chromosome, complete genome.
Accession	NC_007722
Length	3,052,398

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The map label for this gene is fadB1 [H]

Identifier: 85374834

GI number: 85374834

Start: 2035813

End: 2036595

Strand: Direct

Name: fadB1 [H]

Synonym: ELI_10035

Alternate gene names: 85374834

Gene position: 2035813-2036595 (Clockwise)

Preceding gene: 85374833

Following gene: 85374835

Centisome position: 66.7

GC content: 61.56

Gene sequence:

>783_bases
ATGAGCTACGAAACCATCCTGACCGAAACCGACGGCGCGGTGACCATCATCACGCTCAACCGGCCCAAGGCGTTGAATGC
ACTCTCAAGCGTCGTGCTGGAAGAACTGATCGACGCCTTCGCTGCGTATCAGGCAGACGACAGCCAGCTTTGCGCGATCC
TGACCGGAAGCGGCGACAAGGCCTTTGCCGCAGGTGCCGACATCAAGGAAATGAGCGAGAAGGCCGCGGCCGATTTCTAC
CTGCAGGACTTCTTCGCCAAGTGGACCAGCCATATCGTCAAGACCACGCGCAAGCCGTGGATCGCAGCGGTCAATGGCTT
CGCGCTGGGCGGCGGGTGCGAGCTGGCCATGATGGCCGATTTCATCATCGCCAGCGAAAACGCCAAGTTCGGCCAGCCCG
AGATCAAGCTCGGCGTCGCCCCCGGCATGGGCGGTAGCCAGCGGCTGACGCGCGCGGTCGGCAAGTCGAAGGCCATGGAA
ATGTGCTTGACCGGCCGGATGATGGGTGCGGAAGAGGCCGAGCGCAGCAACCTTGTCGCCAAGGTCGTGCCGCATGAGGA
ACTGATGGCCGAAGCCAAAAAGACCGCCGCACTGATCGCCTCGATGCCGCCGATGGCCGCGATTGCGAACAAGGAAATGG
TCAACAGCGCTTTCGAAATGACACTCGACCAAGGCTTGGTGCAAGAGCGCCGCCTGTTCCAGATCCTCACCGCGAGCGAG
GACAAGAAGGAAGGCATGGCCGCGTTTATCGACAAGCGTGACGGAAACTGGAAGGGGCGCTGA

Upstream 100 bases:

>100_bases
GCTGACCTGATGGTCGTCCCAGCGCAGGCTGGGATCTCTGTCCGCTTGGTCGGACTTTGCTGAGAAAGATCCCGGCCTTC
GCTGGGATGACGGAGTTGAA

Downstream 100 bases:

>100_bases
CGCCATGAAGGGGTATTCGGTCCTGCTCGTCCTCCTGTGGCTGGCGCTGGCTGCTTATACTGCCGTCACTGTGGCCAATC
ATGGACTGGGGCTGCTGCCG

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSYETILTETDGAVTIITLNRPKALNALSSVVLEELIDAFAAYQADDSQLCAILTGSGDKAFAAGADIKEMSEKAAADFY
LQDFFAKWTSHIVKTTRKPWIAAVNGFALGGGCELAMMADFIIASENAKFGQPEIKLGVAPGMGGSQRLTRAVGKSKAME
MCLTGRMMGAEEAERSNLVAKVVPHEELMAEAKKTAALIASMPPMAAIANKEMVNSAFEMTLDQGLVQERRLFQILTASE
DKKEGMAAFIDKRDGNWKGR

Sequences:

>Translated_260_residues
MSYETILTETDGAVTIITLNRPKALNALSSVVLEELIDAFAAYQADDSQLCAILTGSGDKAFAAGADIKEMSEKAAADFY
LQDFFAKWTSHIVKTTRKPWIAAVNGFALGGGCELAMMADFIIASENAKFGQPEIKLGVAPGMGGSQRLTRAVGKSKAME
MCLTGRMMGAEEAERSNLVAKVVPHEELMAEAKKTAALIASMPPMAAIANKEMVNSAFEMTLDQGLVQERRLFQILTASE
DKKEGMAAFIDKRDGNWKGR
>Mature_259_residues
SYETILTETDGAVTIITLNRPKALNALSSVVLEELIDAFAAYQADDSQLCAILTGSGDKAFAAGADIKEMSEKAAADFYL
QDFFAKWTSHIVKTTRKPWIAAVNGFALGGGCELAMMADFIIASENAKFGQPEIKLGVAPGMGGSQRLTRAVGKSKAMEM
CLTGRMMGAEEAERSNLVAKVVPHEELMAEAKKTAALIASMPPMAAIANKEMVNSAFEMTLDQGLVQERRLFQILTASED
KKEGMAAFIDKRDGNWKGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=260, Percent_Identity=50.7692307692308, Blast_Score=241, Evalue=7e-64,
Organism=Homo sapiens, GI31542718, Length=262, Percent_Identity=31.6793893129771, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI37594469, Length=191, Percent_Identity=31.9371727748691, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI37594471, Length=191, Percent_Identity=31.9371727748691, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI70995211, Length=224, Percent_Identity=32.1428571428571, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI4502327, Length=259, Percent_Identity=32.046332046332, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI20127408, Length=180, Percent_Identity=36.1111111111111, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI68989263, Length=285, Percent_Identity=27.719298245614, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI45643119, Length=260, Percent_Identity=27.6923076923077, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI260275230, Length=260, Percent_Identity=27.6923076923077, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI260274832, Length=260, Percent_Identity=27.6923076923077, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI150378541, Length=259, Percent_Identity=31.2741312741313, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI25453481, Length=259, Percent_Identity=25.4826254826255, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI51538573, Length=259, Percent_Identity=25.4826254826255, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI4757966, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI51538581, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4757968, Length=259, Percent_Identity=24.7104247104247, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI49355787, Length=259, Percent_Identity=24.7104247104247, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI221136756, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221136753, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221307494, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI157694516, Length=238, Percent_Identity=24.7899159663866, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI213417737, Length=238, Percent_Identity=24.7899159663866, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI62530384, Length=224, Percent_Identity=25.8928571428571, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=43.7246963562753, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=41.3533834586466, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1788597, Length=265, Percent_Identity=33.9622641509434, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=33.587786259542, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082183, Length=264, Percent_Identity=31.0606060606061, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1790281, Length=180, Percent_Identity=35.5555555555556, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=31.25, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=50.2024291497976, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=50.4065040650407, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17560910, Length=219, Percent_Identity=37.4429223744292, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17540714, Length=235, Percent_Identity=34.468085106383, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25144157, Length=192, Percent_Identity=35.9375, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144160, Length=192, Percent_Identity=35.9375, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17535521, Length=218, Percent_Identity=28.8990825688073, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=216, Percent_Identity=30.0925925925926, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=223, Percent_Identity=28.6995515695067, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=233, Percent_Identity=26.1802575107296, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=243, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=241, Percent_Identity=28.6307053941909, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25144276, Length=233, Percent_Identity=25.3218884120172, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508953, Length=233, Percent_Identity=25.3218884120172, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=233, Percent_Identity=25.3218884120172, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=204, Percent_Identity=29.9019607843137, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI20129971, Length=255, Percent_Identity=53.3333333333333, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24653477, Length=255, Percent_Identity=53.3333333333333, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI21357171, Length=250, Percent_Identity=32.8, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24653139, Length=266, Percent_Identity=31.203007518797, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24650670, Length=213, Percent_Identity=32.3943661971831, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922422, Length=267, Percent_Identity=31.4606741573034, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=32.1428571428571, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571730, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571729, Length=161, Percent_Identity=32.9192546583851, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24654903, Length=218, Percent_Identity=27.0642201834862, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19921000, Length=180, Percent_Identity=31.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583077, Length=176, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583079, Length=176, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28013; Mature: 27881

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYETILTETDGAVTIITLNRPKALNALSSVVLEELIDAFAAYQADDSQLCAILTGSGDK
CCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
AFAAGADIKEMSEKAAADFYLQDFFAKWTSHIVKTTRKPWIAAVNGFALGGGCELAMMAD
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCCHHHHHHH
FIIASENAKFGQPEIKLGVAPGMGGSQRLTRAVGKSKAMEMCLTGRMMGAEEAERSNLVA
HHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEE
KVVPHEELMAEAKKTAALIASMPPMAAIANKEMVNSAFEMTLDQGLVQERRLFQILTASE
EECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DKKEGMAAFIDKRDGNWKGR
CHHCCCEEEHCCCCCCCCCC
>Mature Secondary Structure 
SYETILTETDGAVTIITLNRPKALNALSSVVLEELIDAFAAYQADDSQLCAILTGSGDK
CCCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
AFAAGADIKEMSEKAAADFYLQDFFAKWTSHIVKTTRKPWIAAVNGFALGGGCELAMMAD
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCCHHHHHHH
FIIASENAKFGQPEIKLGVAPGMGGSQRLTRAVGKSKAMEMCLTGRMMGAEEAERSNLVA
HHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEE
KVVPHEELMAEAKKTAALIASMPPMAAIANKEMVNSAFEMTLDQGLVQERRLFQILTASE
EECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DKKEGMAAFIDKRDGNWKGR
CHHCCCEEEHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]