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The map label for this gene is surA [H]

Identifier: 85374605

GI number: 85374605

Start: 1810053

End: 1811474

Strand: Direct

Name: surA [H]

Synonym: ELI_08890

Alternate gene names: 85374605

Gene position: 1810053-1811474 (Clockwise)

Preceding gene: 85374604

Following gene: 85374606

Centisome position: 59.3

GC content: 63.5

Gene sequence:

>1422_bases
ATGTTGGACGGGAATATGACGGCGGGGCGCAAGACAGGAATGATTGTGTTCACAACCGCTCTACCGACCGTTTTTGCCCG
CACTGCAACGGCACTGGCCGCTTTCAGCCTCGCCGCGTCTCCGATCGCGATTGCCGCCCAGGAGGCAGCGCAGGATGCCG
ACCAACCGGCGGCGGCTCCGAACCCGCTGGGCATTCCGGACAATTTCTCGCTGCTGGGCGAATCGAACCCCAATGTCCGC
AAGGCAACCGCCGTCGTAAACGGCTCGGTCATCACCGGTACCGATATCGATCACCGCACAGCGCTGGTGGTCGCCTCCGC
GCAGGGTGAACTCGCCGAGGAAGAGATGGTTCGCGTGCGGATGCAGGTGCTGCGCAACCTGATCGACGAGACGCTGCAGG
TGCAGGAAGCAGCGGCGCAGGAGATCAATATCACTGCTGACGAAGTGAACCAGCGCTATGCCCAGCTGGCGGCGCAGAAT
TTCGGCAACCAGCCCGACGCGATGGATGCCTACCTGCTGTCGATCGGCTCTTCCCCCGCTTCGCTCAAGCGCCAGATCCA
GGGTGAGCTCGCCTGGCAGCGCCTGCTGCGCCGCAACATCGCGCCCTTCATCAATGTCTCCGAAGAGGAAGTGAACGACC
TCATCAAGCGGCTCGAGGAATCGCGCGGTACGGAAGAATACCACATCATGGAAATCTACCTGCCGGCGACCGCCGAGACG
CGGCAGGCGGTGATCCAGAACGGGCAGCAGATCATGGAGCAGCTGCGCGGCGGAGCGAGCTTCCTCGCCTATGCGCGCCA
GTTCTCCGAAAGCTCGACCGCGGCAACCGGCGGCGACCTGGGCTTCGTGCGGCTGGAAACGCTTCCGGCCGAGATGGCCA
CTGCTGCACAAACGATGCAACCCGGCCAGCTGACCGGTCCGGTCGAAATTCCGGGCGGTTTCGTGATCATTTATCTGCGT
GACAAGCGTGCCGTCCTGACCGCCGATCCGCGCGATGCGCTCCTGAGCCTCAAGCAGATTTCGATCTCGTTCGAAGAGGG
CATCTCGCAAGAGGAGGCGACGTCGAAAGTCGAAGCTTTCGCCGGCGCCGTCGGCTCGATCCGCGGCTGCGGCGATGCCG
AGCGTGCCGCGCAGACCGTCGGTGCCGAAGTCGTGACCAACGACCAGATCCGGGTCCGCGACTTGCCCGAGCAATTGCAG
GGTTCGATGCTGGAATTACAGGTCGGCCAGGCGACCCAGCCGTTCGGATCGCTGCAGGAGGGTGTCCGTGTGTTGCTTCT
GTGCGGTCGCGACGATCCGCAGGCTGCCGACGGACCGAGCTTCGACGTTCTGATGAGCCGGATGGAAGAGGAGCGCATCC
AGAAGCGCGCCCGCCGTTACCTGCGCGATCTGCGCAACGACGCCTATATCGAGTACAACTGA

Upstream 100 bases:

>100_bases
TTGGCTTGACCAGCCAAACGCGCTAGATCGCGCCACTCATCAAGGGTTCAGCCACGTTTCGCCATGCGGCACGGCCACGA
ATTTGCCCTGTCATGTCCAT

Downstream 100 bases:

>100_bases
GCGGGTGGGCGAGCCGCAGCGCCCGCTCGCCGTTTCGCTGGGTGATCCGGCCGGCATCGGACCGGAAATCATCGTCCATG
CCTGGCGCATGCGCGATTCC

Product: peptidyl-prolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MLDGNMTAGRKTGMIVFTTALPTVFARTATALAAFSLAASPIAIAAQEAAQDADQPAAAPNPLGIPDNFSLLGESNPNVR
KATAVVNGSVITGTDIDHRTALVVASAQGELAEEEMVRVRMQVLRNLIDETLQVQEAAAQEINITADEVNQRYAQLAAQN
FGNQPDAMDAYLLSIGSSPASLKRQIQGELAWQRLLRRNIAPFINVSEEEVNDLIKRLEESRGTEEYHIMEIYLPATAET
RQAVIQNGQQIMEQLRGGASFLAYARQFSESSTAATGGDLGFVRLETLPAEMATAAQTMQPGQLTGPVEIPGGFVIIYLR
DKRAVLTADPRDALLSLKQISISFEEGISQEEATSKVEAFAGAVGSIRGCGDAERAAQTVGAEVVTNDQIRVRDLPEQLQ
GSMLELQVGQATQPFGSLQEGVRVLLLCGRDDPQAADGPSFDVLMSRMEEERIQKRARRYLRDLRNDAYIEYN

Sequences:

>Translated_473_residues
MLDGNMTAGRKTGMIVFTTALPTVFARTATALAAFSLAASPIAIAAQEAAQDADQPAAAPNPLGIPDNFSLLGESNPNVR
KATAVVNGSVITGTDIDHRTALVVASAQGELAEEEMVRVRMQVLRNLIDETLQVQEAAAQEINITADEVNQRYAQLAAQN
FGNQPDAMDAYLLSIGSSPASLKRQIQGELAWQRLLRRNIAPFINVSEEEVNDLIKRLEESRGTEEYHIMEIYLPATAET
RQAVIQNGQQIMEQLRGGASFLAYARQFSESSTAATGGDLGFVRLETLPAEMATAAQTMQPGQLTGPVEIPGGFVIIYLR
DKRAVLTADPRDALLSLKQISISFEEGISQEEATSKVEAFAGAVGSIRGCGDAERAAQTVGAEVVTNDQIRVRDLPEQLQ
GSMLELQVGQATQPFGSLQEGVRVLLLCGRDDPQAADGPSFDVLMSRMEEERIQKRARRYLRDLRNDAYIEYN
>Mature_473_residues
MLDGNMTAGRKTGMIVFTTALPTVFARTATALAAFSLAASPIAIAAQEAAQDADQPAAAPNPLGIPDNFSLLGESNPNVR
KATAVVNGSVITGTDIDHRTALVVASAQGELAEEEMVRVRMQVLRNLIDETLQVQEAAAQEINITADEVNQRYAQLAAQN
FGNQPDAMDAYLLSIGSSPASLKRQIQGELAWQRLLRRNIAPFINVSEEEVNDLIKRLEESRGTEEYHIMEIYLPATAET
RQAVIQNGQQIMEQLRGGASFLAYARQFSESSTAATGGDLGFVRLETLPAEMATAAQTMQPGQLTGPVEIPGGFVIIYLR
DKRAVLTADPRDALLSLKQISISFEEGISQEEATSKVEAFAGAVGSIRGCGDAERAAQTVGAEVVTNDQIRVRDLPEQLQ
GSMLELQVGQATQPFGSLQEGVRVLLLCGRDDPQAADGPSFDVLMSRMEEERIQKRARRYLRDLRNDAYIEYN

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=259, Percent_Identity=24.3243243243243, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 51266; Mature: 51266

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDGNMTAGRKTGMIVFTTALPTVFARTATALAAFSLAASPIAIAAQEAAQDADQPAAAP
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
NPLGIPDNFSLLGESNPNVRKATAVVNGSVITGTDIDHRTALVVASAQGELAEEEMVRVR
CCCCCCCCCEECCCCCCCCEEEEEEEECCEEECCCCCCCEEEEEECCCCCHHHHHHHHHH
MQVLRNLIDETLQVQEAAAQEINITADEVNQRYAQLAAQNFGNQPDAMDAYLLSIGSSPA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHH
SLKRQIQGELAWQRLLRRNIAPFINVSEEEVNDLIKRLEESRGTEEYHIMEIYLPATAET
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
RQAVIQNGQQIMEQLRGGASFLAYARQFSESSTAATGGDLGFVRLETLPAEMATAAQTMQ
HHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCC
PGQLTGPVEIPGGFVIIYLRDKRAVLTADPRDALLSLKQISISFEEGISQEEATSKVEAF
CCCCCCCEECCCCEEEEEEECCCEEEECCCHHHHHHHHHHEEEHHHCCCHHHHHHHHHHH
AGAVGSIRGCGDAERAAQTVGAEVVTNDQIRVRDLPEQLQGSMLELQVGQATQPFGSLQE
HHHHHCCCCCCCHHHHHHHHCCCEEECCCEEECCCCHHHCCCEEEEEECCCCCCHHHHHH
GVRVLLLCGRDDPQAADGPSFDVLMSRMEEERIQKRARRYLRDLRNDAYIEYN
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MLDGNMTAGRKTGMIVFTTALPTVFARTATALAAFSLAASPIAIAAQEAAQDADQPAAAP
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
NPLGIPDNFSLLGESNPNVRKATAVVNGSVITGTDIDHRTALVVASAQGELAEEEMVRVR
CCCCCCCCCEECCCCCCCCEEEEEEEECCEEECCCCCCCEEEEEECCCCCHHHHHHHHHH
MQVLRNLIDETLQVQEAAAQEINITADEVNQRYAQLAAQNFGNQPDAMDAYLLSIGSSPA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHH
SLKRQIQGELAWQRLLRRNIAPFINVSEEEVNDLIKRLEESRGTEEYHIMEIYLPATAET
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
RQAVIQNGQQIMEQLRGGASFLAYARQFSESSTAATGGDLGFVRLETLPAEMATAAQTMQ
HHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCC
PGQLTGPVEIPGGFVIIYLRDKRAVLTADPRDALLSLKQISISFEEGISQEEATSKVEAF
CCCCCCCEECCCCEEEEEEECCCEEEECCCHHHHHHHHHHEEEHHHCCCHHHHHHHHHHH
AGAVGSIRGCGDAERAAQTVGAEVVTNDQIRVRDLPEQLQGSMLELQVGQATQPFGSLQE
HHHHHCCCCCCCHHHHHHHHCCCEEECCCEEECCCCHHHCCCEEEEEECCCCCCHHHHHH
GVRVLLLCGRDDPQAADGPSFDVLMSRMEEERIQKRARRYLRDLRNDAYIEYN
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]