Click here to switch to the map view.

The map label for this gene is ycfH [C]

Identifier: 85374073

GI number: 85374073

Start: 1295963

End: 1296739

Strand: Direct

Name: ycfH [C]

Synonym: ELI_06230

Alternate gene names: 85374073

Gene position: 1295963-1296739 (Clockwise)

Preceding gene: 85374072

Following gene: 85374074

Centisome position: 42.46

GC content: 63.06

Gene sequence:

>777_bases
ATGCTGGTCGATAGCCATTGCCACCTGCAGTACAAAGGCCTGGTCGAAGATCAGCAGGCCGTGCTCGAACGCGCGCGGGC
AGCAGGCGTGCAGGGCATGCTCAATATCTCGACCAAGAGCGCCGAGTGGGACGATGTGGTCGGCACTGCGCAGCGCGAGC
CCGATGTCTGGGCAAGCGTCGGCATTCATCCGCACGAGGCCGATGCGCACGAGGATCTCGGCCGCGACAAACTGCTCGCC
GCGACGAAACAGGACAAGGTCGTCGGCATCGGCGAAACCGGGCTCGATTATTATTACGACCGCTCCGACCGCGACGTTCA
GAAGGCGCTGTTCCGCATGCATATCGGCGTCGCGCGCGAGACGCAGTTGCCGGTCATCATCCACACGCGTGATGCCGAGG
ACGACACGGCGCAGATCCTGACGGAAGAAATGGAGCAGGGCGCGTTTCCGGCGCTGATCCACTGCTTTACCGCCTCGGCA
GATTTCGGGCGCACGGTGCTCGATCTCGGCCTTTCGATCTCGCTCTCGGGTATCGTCACGTTCAAGAATGCCAGGGACTT
GCAGGCTGTAGCCAAGAATGTGCCGAAGGAGCGGCTGCTGGTCGAAACCGACAGCCCCTTCCTCGCGCCCGTGCCGCATC
GCGGCAAGCCGTGCGAACCGGCCTTCGTCCGCAATACGGCGGAATTCCTGGCCGACCTGCGCGGCGAAACGCTGGAACAT
CTCGCCGAAACCACGACCCGCAACTTCTTCGAACTGTTTGACAGAGCGGCCGCGTGA

Upstream 100 bases:

>100_bases
GGGAAGGGTGGTTCAACCAGCTCGTCGCCGAAGGCTTTACCGTGCCCAAGCCGACCCCCGCCTTCCCGCGCCTCGAAATG
CCAGAGAGCGAGGATGCCTG

Downstream 100 bases:

>100_bases
AAGTCGTGATGCTCGGAACGGGTACGTCGACCGGCGTGCCGCGCATCAATGGCGACTGGGGCGATTGCGATCCGAACGAG
CCGCGCAACCGCCGCAGCCG

Product: Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLVDSHCHLQYKGLVEDQQAVLERARAAGVQGMLNISTKSAEWDDVVGTAQREPDVWASVGIHPHEADAHEDLGRDKLLA
ATKQDKVVGIGETGLDYYYDRSDRDVQKALFRMHIGVARETQLPVIIHTRDAEDDTAQILTEEMEQGAFPALIHCFTASA
DFGRTVLDLGLSISLSGIVTFKNARDLQAVAKNVPKERLLVETDSPFLAPVPHRGKPCEPAFVRNTAEFLADLRGETLEH
LAETTTRNFFELFDRAAA

Sequences:

>Translated_258_residues
MLVDSHCHLQYKGLVEDQQAVLERARAAGVQGMLNISTKSAEWDDVVGTAQREPDVWASVGIHPHEADAHEDLGRDKLLA
ATKQDKVVGIGETGLDYYYDRSDRDVQKALFRMHIGVARETQLPVIIHTRDAEDDTAQILTEEMEQGAFPALIHCFTASA
DFGRTVLDLGLSISLSGIVTFKNARDLQAVAKNVPKERLLVETDSPFLAPVPHRGKPCEPAFVRNTAEFLADLRGETLEH
LAETTTRNFFELFDRAAA
>Mature_258_residues
MLVDSHCHLQYKGLVEDQQAVLERARAAGVQGMLNISTKSAEWDDVVGTAQREPDVWASVGIHPHEADAHEDLGRDKLLA
ATKQDKVVGIGETGLDYYYDRSDRDVQKALFRMHIGVARETQLPVIIHTRDAEDDTAQILTEEMEQGAFPALIHCFTASA
DFGRTVLDLGLSISLSGIVTFKNARDLQAVAKNVPKERLLVETDSPFLAPVPHRGKPCEPAFVRNTAEFLADLRGETLEH
LAETTTRNFFELFDRAAA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=27.7153558052434, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI225903424, Length=270, Percent_Identity=24.8148148148148, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=27.7153558052434, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=27.9411764705882, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI226061614, Length=256, Percent_Identity=27.34375, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI14042943, Length=277, Percent_Identity=26.3537906137184, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI225903439, Length=240, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=27.7533039647577, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=45.3125, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=28.0155642023346, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=29.0697674418605, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=278, Percent_Identity=28.7769784172662, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=24.8091603053435, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=289, Percent_Identity=26.643598615917, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=193, Percent_Identity=30.0518134715026, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648690, Length=289, Percent_Identity=28.3737024221453, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221330018, Length=275, Percent_Identity=25.8181818181818, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24586117, Length=275, Percent_Identity=25.8181818181818, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 28561; Mature: 28561

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLQYKGLVEDQQAVLERARAAGVQGMLNISTKSAEWDDVVGTAQREPDVWASV
CCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCCCCEEC
GIHPHEADAHEDLGRDKLLAATKQDKVVGIGETGLDYYYDRSDRDVQKALFRMHIGVARE
CCCCCCCCHHHHCCCHHHHHHCCCCCEEECCCCCCCCEECCCCHHHHHHHHHHHHCCCCC
TQLPVIIHTRDAEDDTAQILTEEMEQGAFPALIHCFTASADFGRTVLDLGLSISLSGIVT
CCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCHHHHHHCCEEEEEEEEE
FKNARDLQAVAKNVPKERLLVETDSPFLAPVPHRGKPCEPAFVRNTAEFLADLRGETLEH
ECCCHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAETTTRNFFELFDRAAA
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVDSHCHLQYKGLVEDQQAVLERARAAGVQGMLNISTKSAEWDDVVGTAQREPDVWASV
CCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCCCCEEC
GIHPHEADAHEDLGRDKLLAATKQDKVVGIGETGLDYYYDRSDRDVQKALFRMHIGVARE
CCCCCCCCHHHHCCCHHHHHHCCCCCEEECCCCCCCCEECCCCHHHHHHHHHHHHCCCCC
TQLPVIIHTRDAEDDTAQILTEEMEQGAFPALIHCFTASADFGRTVLDLGLSISLSGIVT
CCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCHHHHHHCCEEEEEEEEE
FKNARDLQAVAKNVPKERLLVETDSPFLAPVPHRGKPCEPAFVRNTAEFLADLRGETLEH
ECCCHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAETTTRNFFELFDRAAA
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]