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The map label for this gene is mraY

Identifier: 85373183

GI number: 85373183

Start: 399349

End: 400419

Strand: Direct

Name: mraY

Synonym: ELI_01780

Alternate gene names: 85373183

Gene position: 399349-400419 (Clockwise)

Preceding gene: 85373182

Following gene: 85373184

Centisome position: 13.08

GC content: 63.68

Gene sequence:

>1071_bases
ATGCTCTATCTGATTGCCGAGTGGTTGGGTTTCGAAGGGGCGCTGAACCTCATCCGTTACCAGACGTTCCGCACCGGGGC
GACGCTGATGACCGCGCTGGTGATCGGGTTGATCATCGGGCCGCGCTTCATCAACATGCTGCGCGTGCGGCAGGGAAAAG
GCCAGCCGATCCGCGACGACGGGCCGCAGAGCCATCTCGCCAAGCGCGGCACGCCGACCATGGGCGGGCTGATGATTATC
GTTTCGCTGGTCCTGTCGCTGGTGTTGTGGATGGACCTGCGCAGCCCCTTCGTGTGGGCCTGCCTCGCCGTCACCGTCGG
CTTCGGGCTGATCGGCTTCCTCGACGATCTCGACAAGGTCACCAAGAACAGCCACCGCGGTGTCTCGGCCAAGGTCCGCC
TGCTGATGGAATTCCTCGTCGCCGGGATCGCCAGCTACATCATCGTCAGCCAGATCAATACCTGGCTCTACGTGCCCTTC
GTTTCCGACCGCGCGATCCCGCTGGGGCCGTTCTACTATGTCTTCGCCGCGGTCGTGATCGTCGGCGCGGGCAACGCCGT
GAACCTCACCGACGGGCTCGACGGGCTGGCGATCATGCCGGTCATCATCGCGGCGGGCACCTTCGCCATCATCGCCTATC
TGGCGGGCCGCGTGGACTATTCGGAATATCTCGGCATTCCGCATGTGCCCGGTGCGGGCGAGCTGGCGATATTCTGCGCG
GCGATCATGGGGGCGGGGCTGGCCTTCCTATGGTTCAACGCGCCCCCTGCGGCGGTTTTCATGGGCGATACCGGCAGCCT
CGCTCTCGGCGGAGCATTGGGCGCGATCGCCGTTGCGAGCCATCACGAAATCGTCCTCGCCATCGTCGGCGGGCTGTTCG
TGTTCGAAGCGCTTAGCGTCATCATCCAGGTCTTCTGGTTCAAGCGCACCGGCAAACGCGTGTTTCGCATGGCGCCCATC
CACCACCATTTCGAACAGCTCGGCTGGAGCGAGAGCAAGGTCGTGATCCGCTTCTGGATCGTGTCCATCGTGCTCGCGCT
GATGGGTCTTGCCACACTGAAGCTGCGATGA

Upstream 100 bases:

>100_bases
GGCGATGCGATTCTGGTCAAGGGCTCCAATTCGATCGGGCTCGGCAAGCTGGTGGATCACTTCACCAGGCGCGTTTGATT
GAGGGGGCCGGGACGACCGA

Downstream 100 bases:

>100_bases
TCACCTGCCCCGCCTGGTCCGGCAAGAGTTTTGCCGTCCTTGGCCTGGCCCGCTCGGGCCAGGCGGCAGCAGAGGCGCTG
CTGGCGAGCGGGGCGGACGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MLYLIAEWLGFEGALNLIRYQTFRTGATLMTALVIGLIIGPRFINMLRVRQGKGQPIRDDGPQSHLAKRGTPTMGGLMII
VSLVLSLVLWMDLRSPFVWACLAVTVGFGLIGFLDDLDKVTKNSHRGVSAKVRLLMEFLVAGIASYIIVSQINTWLYVPF
VSDRAIPLGPFYYVFAAVVIVGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRVDYSEYLGIPHVPGAGELAIFCA
AIMGAGLAFLWFNAPPAAVFMGDTGSLALGGALGAIAVASHHEIVLAIVGGLFVFEALSVIIQVFWFKRTGKRVFRMAPI
HHHFEQLGWSESKVVIRFWIVSIVLALMGLATLKLR

Sequences:

>Translated_356_residues
MLYLIAEWLGFEGALNLIRYQTFRTGATLMTALVIGLIIGPRFINMLRVRQGKGQPIRDDGPQSHLAKRGTPTMGGLMII
VSLVLSLVLWMDLRSPFVWACLAVTVGFGLIGFLDDLDKVTKNSHRGVSAKVRLLMEFLVAGIASYIIVSQINTWLYVPF
VSDRAIPLGPFYYVFAAVVIVGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRVDYSEYLGIPHVPGAGELAIFCA
AIMGAGLAFLWFNAPPAAVFMGDTGSLALGGALGAIAVASHHEIVLAIVGGLFVFEALSVIIQVFWFKRTGKRVFRMAPI
HHHFEQLGWSESKVVIRFWIVSIVLALMGLATLKLR
>Mature_356_residues
MLYLIAEWLGFEGALNLIRYQTFRTGATLMTALVIGLIIGPRFINMLRVRQGKGQPIRDDGPQSHLAKRGTPTMGGLMII
VSLVLSLVLWMDLRSPFVWACLAVTVGFGLIGFLDDLDKVTKNSHRGVSAKVRLLMEFLVAGIASYIIVSQINTWLYVPF
VSDRAIPLGPFYYVFAAVVIVGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRVDYSEYLGIPHVPGAGELAIFCA
AIMGAGLAFLWFNAPPAAVFMGDTGSLALGGALGAIAVASHHEIVLAIVGGLFVFEALSVIIQVFWFKRTGKRVFRMAPI
HHHFEQLGWSESKVVIRFWIVSIVLALMGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=52.3545706371191, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_ERYLH (Q2NCZ3)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457245.1
- STRING:   Q2NCZ3
- GeneID:   3869322
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_01780
- NMPDR:   fig|314225.3.peg.2733
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q2NCZ3
- ProtClustDB:   PRK00108
- BioCyc:   ELIT314225:ELI_01780-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38500; Mature: 38500

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12fb937c)-; HASH(0x1377f75c)-; HASH(0x13782c0c)-; HASH(0x13780f38)-; HASH(0x13780428)-; HASH(0x1378290c)-; HASH(0x13781f4c)-; HASH(0x1377f594)-; HASH(0x13780fc8)-; HASH(0x13780278)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLIAEWLGFEGALNLIRYQTFRTGATLMTALVIGLIIGPRFINMLRVRQGKGQPIRDD
CEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQSHLAKRGTPTMGGLMIIVSLVLSLVLWMDLRSPFVWACLAVTVGFGLIGFLDDLDKV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKNSHRGVSAKVRLLMEFLVAGIASYIIVSQINTWLYVPFVSDRAIPLGPFYYVFAAVVI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHH
VGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRVDYSEYLGIPHVPGAGELAIFCA
HCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHH
AIMGAGLAFLWFNAPPAAVFMGDTGSLALGGALGAIAVASHHEIVLAIVGGLFVFEALSV
HHHHCCCEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IIQVFWFKRTGKRVFRMAPIHHHFEQLGWSESKVVIRFWIVSIVLALMGLATLKLR
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLYLIAEWLGFEGALNLIRYQTFRTGATLMTALVIGLIIGPRFINMLRVRQGKGQPIRDD
CEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQSHLAKRGTPTMGGLMIIVSLVLSLVLWMDLRSPFVWACLAVTVGFGLIGFLDDLDKV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKNSHRGVSAKVRLLMEFLVAGIASYIIVSQINTWLYVPFVSDRAIPLGPFYYVFAAVVI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHH
VGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRVDYSEYLGIPHVPGAGELAIFCA
HCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHH
AIMGAGLAFLWFNAPPAAVFMGDTGSLALGGALGAIAVASHHEIVLAIVGGLFVFEALSV
HHHHCCCEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IIQVFWFKRTGKRVFRMAPIHHHFEQLGWSESKVVIRFWIVSIVLALMGLATLKLR
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA