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The map label for this gene is map [H]

Identifier: 85373165

GI number: 85373165

Start: 383633

End: 384463

Strand: Direct

Name: map [H]

Synonym: ELI_01690

Alternate gene names: 85373165

Gene position: 383633-384463 (Clockwise)

Preceding gene: 85373164

Following gene: 85373168

Centisome position: 12.57

GC content: 62.21

Gene sequence:

>831_bases
ATGAGCGAATATCAGGTCATCACCGCCGACGACGACGTCCAGCGCGACGGCACCATCAAATTGCACGGGCCCGAGGGGTT
CGAAGGCATGCGCAAGGCCGGTCGCCTCGCTGCGGACATCCTCGATGCGACCGTCGAACTGGTCGAGCCGGGGGTCACTA
CCGAAAGCATCGACGCCGCGATCCGCGGCATGATGCTTGATGCAGGTGCGGTTCCCGCAACGCTGGGGTATCGCGGCTAC
ACGCACAGTTCGTGCATCTCGATCAATCATGTGATCTGCCACGGCATCCCGAGCGAGAAGACGCTCAAGGAAGGCGATAT
CGTCAATATCGACGTCACCCCGCTGCTCGACGGCTGGCATGGCGATACCAGCCGCATGTTCTTCGCTGGCGAACCCCCGC
TCAAGGCGAAGAAGCTGGTCGACGTGACCTATGAATGCCTGATGCTCGGCATCGAAGCGGCATCGAAGCCGGGCGCGCGG
CTCGGCGATATCGGCGCGGCGATCGAAGCCCATGCCCGCCAATATCGCTACGGCGTAGTACGCGAATTTTGCGGCCACGG
CCTCGGCCGTCTGTTTCATGACGCACCCGAAGTGGTGCATGCCGCGAAAGCGGGGACGGGGCCGGAGCTTAAGCCCGGCA
TGTTCTTCACCATCGAACCGATGATCAATCTCGGCAAGCCGTGGGGCAAGGTGCTCAAGGACGGCTGGACCGCGGTGACC
CGAGACAAGTCGCTAAGCGCGCAGTTCGAACATTCGCTCGGCATCACCGAGGACGGAATCGAGATTTTCACGGAAAGCAC
CAAGGGGCTGCACCAGCCGCCCTATGCCTAA

Upstream 100 bases:

>100_bases
GAGCCGGTGATGAAAGCGTTGAAGCCCGCCTATCGCGAGGCTTTCGCCCGGCGCTAGGTCCGTCTCGCATTTTGAGTGCG
GCATCGCTATATCGCGCGTT

Downstream 100 bases:

>100_bases
TTCTCCCGCGCAGCCCGGATGGCTGCGCCGGCGGCGAAGGGCGCGATGCCGCACAGTGCTAGGCTGATGGCACCAGCCAG
CGCAATGCCGGTCGCATCGC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSEYQVITADDDVQRDGTIKLHGPEGFEGMRKAGRLAADILDATVELVEPGVTTESIDAAIRGMMLDAGAVPATLGYRGY
THSSCISINHVICHGIPSEKTLKEGDIVNIDVTPLLDGWHGDTSRMFFAGEPPLKAKKLVDVTYECLMLGIEAASKPGAR
LGDIGAAIEAHARQYRYGVVREFCGHGLGRLFHDAPEVVHAAKAGTGPELKPGMFFTIEPMINLGKPWGKVLKDGWTAVT
RDKSLSAQFEHSLGITEDGIEIFTESTKGLHQPPYA

Sequences:

>Translated_276_residues
MSEYQVITADDDVQRDGTIKLHGPEGFEGMRKAGRLAADILDATVELVEPGVTTESIDAAIRGMMLDAGAVPATLGYRGY
THSSCISINHVICHGIPSEKTLKEGDIVNIDVTPLLDGWHGDTSRMFFAGEPPLKAKKLVDVTYECLMLGIEAASKPGAR
LGDIGAAIEAHARQYRYGVVREFCGHGLGRLFHDAPEVVHAAKAGTGPELKPGMFFTIEPMINLGKPWGKVLKDGWTAVT
RDKSLSAQFEHSLGITEDGIEIFTESTKGLHQPPYA
>Mature_275_residues
SEYQVITADDDVQRDGTIKLHGPEGFEGMRKAGRLAADILDATVELVEPGVTTESIDAAIRGMMLDAGAVPATLGYRGYT
HSSCISINHVICHGIPSEKTLKEGDIVNIDVTPLLDGWHGDTSRMFFAGEPPLKAKKLVDVTYECLMLGIEAASKPGARL
GDIGAAIEAHARQYRYGVVREFCGHGLGRLFHDAPEVVHAAKAGTGPELKPGMFFTIEPMINLGKPWGKVLKDGWTAVTR
DKSLSAQFEHSLGITEDGIEIFTESTKGLHQPPYA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=247, Percent_Identity=48.582995951417, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=41.1290322580645, Blast_Score=186, Evalue=1e-47,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=50.4032258064516, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71996291, Length=248, Percent_Identity=43.5483870967742, Blast_Score=203, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=41.9607843137255, Blast_Score=213, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21355531, Length=263, Percent_Identity=42.5855513307985, Blast_Score=212, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24583427, Length=237, Percent_Identity=43.0379746835443, Blast_Score=192, Evalue=1e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29768; Mature: 29637

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYQVITADDDVQRDGTIKLHGPEGFEGMRKAGRLAADILDATVELVEPGVTTESIDAA
CCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IRGMMLDAGAVPATLGYRGYTHSSCISINHVICHGIPSEKTLKEGDIVNIDVTPLLDGWH
HHHHHEECCCCCHHHCCCCCCCCCCEEECEEEEECCCCCCCCCCCCEEEEEECCCCCCCC
GDTSRMFFAGEPPLKAKKLVDVTYECLMLGIEAASKPGARLGDIGAAIEAHARQYRYGVV
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
REFCGHGLGRLFHDAPEVVHAAKAGTGPELKPGMFFTIEPMINLGKPWGKVLKDGWTAVT
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCHHHHHHHCCCCEEE
RDKSLSAQFEHSLGITEDGIEIFTESTKGLHQPPYA
CCCCCCHHHHHCCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SEYQVITADDDVQRDGTIKLHGPEGFEGMRKAGRLAADILDATVELVEPGVTTESIDAA
CCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IRGMMLDAGAVPATLGYRGYTHSSCISINHVICHGIPSEKTLKEGDIVNIDVTPLLDGWH
HHHHHEECCCCCHHHCCCCCCCCCCEEECEEEEECCCCCCCCCCCCEEEEEECCCCCCCC
GDTSRMFFAGEPPLKAKKLVDVTYECLMLGIEAASKPGARLGDIGAAIEAHARQYRYGVV
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
REFCGHGLGRLFHDAPEVVHAAKAGTGPELKPGMFFTIEPMINLGKPWGKVLKDGWTAVT
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCHHHHHHHCCCCEEE
RDKSLSAQFEHSLGITEDGIEIFTESTKGLHQPPYA
CCCCCCHHHHHCCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]