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The map label for this gene is 85373168

Identifier: 85373168

GI number: 85373168

Start: 385759

End: 386064

Strand: Direct

Name: 85373168

Synonym: ELI_01705

Alternate gene names: NA

Gene position: 385759-386064 (Clockwise)

Preceding gene: 85373165

Following gene: 85373172

Centisome position: 12.64

GC content: 60.46

Gene sequence:

>306_bases
ATGACCGTACGAAAACTCAACCAGGAAGAACGCGATACCTGGACCAGCGCGCTGGACGGCTGGGACATGGCCGACGGCAG
GGATGCGATCGAAAAAACCTTCGAATTCGGCGATTTCGTCGAAGCCTGGGGCTTCATGAGCCGCGTCGCGATCCTGGCCG
AAAAGGCCGACCATCATCCCGAATGGTTCAACGTCTACAACCGCGTCGAGATTACGCTCACCACGCATGACGCGGACCCC
GATAACGGCGGCGCACTGTCCAAACGCGACGTGGAACTGGCCAACGCCATCGACGCGCTCGGCTGA

Upstream 100 bases:

>100_bases
GCAGGCGAGGTTGCGTGCGGCGAGGGCGGCGGGCATGGCTTGGGCACTAAGCCAAAGGTCGGGCGTTCACAAGCTGTAGC
CCGCAAGCAGGAGCCCCGCG

Downstream 100 bases:

>100_bases
GAGCCCGAGCACAAATCCGTTCGGGCTGAGCCTGTCTGAGCCCCGCCCTTCTTCTGGCAGGTGCTGCACTAGAAAAGAGT
GCAGCCTTTCGACAAGCTCA

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD [H]

Number of amino acids: Translated: 101; Mature: 100

Protein sequence:

>101_residues
MTVRKLNQEERDTWTSALDGWDMADGRDAIEKTFEFGDFVEAWGFMSRVAILAEKADHHPEWFNVYNRVEITLTTHDADP
DNGGALSKRDVELANAIDALG

Sequences:

>Translated_101_residues
MTVRKLNQEERDTWTSALDGWDMADGRDAIEKTFEFGDFVEAWGFMSRVAILAEKADHHPEWFNVYNRVEITLTTHDADP
DNGGALSKRDVELANAIDALG
>Mature_100_residues
TVRKLNQEERDTWTSALDGWDMADGRDAIEKTFEFGDFVEAWGFMSRVAILAEKADHHPEWFNVYNRVEITLTTHDADPD
NGGALSKRDVELANAIDALG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI4557831, Length=99, Percent_Identity=52.5252525252525, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI134133240, Length=96, Percent_Identity=53.125, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115533705, Length=97, Percent_Identity=54.639175257732, Blast_Score=109, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45549100, Length=99, Percent_Identity=47.4747474747475, Blast_Score=98, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001533 [H]

Pfam domain/function: PF01329 Pterin_4a [H]

EC number: =4.2.1.96 [H]

Molecular weight: Translated: 11414; Mature: 11282

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRKLNQEERDTWTSALDGWDMADGRDAIEKTFEFGDFVEAWGFMSRVAILAEKADHHP
CCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EWFNVYNRVEITLTTHDADPDNGGALSKRDVELANAIDALG
HHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TVRKLNQEERDTWTSALDGWDMADGRDAIEKTFEFGDFVEAWGFMSRVAILAEKADHHP
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EWFNVYNRVEITLTTHDADPDNGGALSKRDVELANAIDALG
HHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA