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The map label for this gene is crt [H]

Identifier: 85373124

GI number: 85373124

Start: 342094

End: 342966

Strand: Direct

Name: crt [H]

Synonym: ELI_01485

Alternate gene names: 85373124

Gene position: 342094-342966 (Clockwise)

Preceding gene: 85373123

Following gene: 85373125

Centisome position: 11.21

GC content: 65.64

Gene sequence:

>873_bases
ATGACCGACTACACCCAGATCCTCGTCGACAAGGCGGATGGCATCGCCACCGTCACGCTCAACCGTCCGGAGAAGATGAA
CGCTTTCACCGGCACGATCATGAGCGAGATCATCACGGCGATGGACGATCTCGACGAGGACGACGATGTCCGCGCGGTGA
TCTTCACCGGGGCCGGAGACCGGGCCTTCTGTGCCGGGGCCGACCTGACGCCCGAAGGCGGGGGTCGCGTGTTCTCCGAC
CCCAACGAAGTCGATGACCTGTCCGACGAGCGCGTGCGCGACGGCGGCGGGCGGCTGACGCTGCGGCTGTTCGACAGCAA
GAAGCCGCTGATCGCGGCCTGCAACGGCGCGGCGGTGGGGGTCGGTTCGACCATGCAATTGCCGATGGATATCCGCCTTG
CGAGCGACAACGCGCGCTACGGCTTCGTCTTTGCGCGGCGCGGGATCGTGCCGGAAGCGGCGTCGAGCTGGTTTCTGCCC
AAGCTCGTCGGCATCAGCCAGGCGCTGGAGTGGTGCTATTCGGGCCGGGTGTTCGATGCGCAGGAAGCGCTCGCCGGGGG
CCTGGTGCGTTCGGTCCATCCGCAGGCCGAACTGATGGACGTGGCGCGCGGGATTGCACGAGAAATCGCCGACAACACCT
CGGCTGTTTCGGTGTCGATGACCCGCGCGATGATGTGGCGCCTGCCGTCGGGCGATCACCCGATGGACGCGCACCGCATC
GATAGCCGCGCGATCTATCGCCTGTCTCGGGGCAAGGATGCGGCGGAAGGTATCGCCAGCTTCCTCGAGAAGCGCGAACC
GAACTATCCCGGCAAGGTCAGCGAAGACATGCCGGACTTCTATCCCTGGTGGGACCAGCCCGAATACAAGTGA

Upstream 100 bases:

>100_bases
TGTTTCGGCAGCGGAATCGGGGCGCTGCTTTTTTCGGCATTGGACCGTGTAACATGCGGTCCATGTGTTCGCCCGATGCG
ATGAATGGAGAGGCTTCGCG

Downstream 100 bases:

>100_bases
GATCGCACACATGAGCAATTGGCATATCGGCGTCCTTGGCGGATCGGGTCTGTACGAGGGGATCGCGCTGGAAGAACAGC
AGGAGATCGAGGTTTCCTCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTDYTQILVDKADGIATVTLNRPEKMNAFTGTIMSEIITAMDDLDEDDDVRAVIFTGAGDRAFCAGADLTPEGGGRVFSD
PNEVDDLSDERVRDGGGRLTLRLFDSKKPLIAACNGAAVGVGSTMQLPMDIRLASDNARYGFVFARRGIVPEAASSWFLP
KLVGISQALEWCYSGRVFDAQEALAGGLVRSVHPQAELMDVARGIAREIADNTSAVSVSMTRAMMWRLPSGDHPMDAHRI
DSRAIYRLSRGKDAAEGIASFLEKREPNYPGKVSEDMPDFYPWWDQPEYK

Sequences:

>Translated_290_residues
MTDYTQILVDKADGIATVTLNRPEKMNAFTGTIMSEIITAMDDLDEDDDVRAVIFTGAGDRAFCAGADLTPEGGGRVFSD
PNEVDDLSDERVRDGGGRLTLRLFDSKKPLIAACNGAAVGVGSTMQLPMDIRLASDNARYGFVFARRGIVPEAASSWFLP
KLVGISQALEWCYSGRVFDAQEALAGGLVRSVHPQAELMDVARGIAREIADNTSAVSVSMTRAMMWRLPSGDHPMDAHRI
DSRAIYRLSRGKDAAEGIASFLEKREPNYPGKVSEDMPDFYPWWDQPEYK
>Mature_289_residues
TDYTQILVDKADGIATVTLNRPEKMNAFTGTIMSEIITAMDDLDEDDDVRAVIFTGAGDRAFCAGADLTPEGGGRVFSDP
NEVDDLSDERVRDGGGRLTLRLFDSKKPLIAACNGAAVGVGSTMQLPMDIRLASDNARYGFVFARRGIVPEAASSWFLPK
LVGISQALEWCYSGRVFDAQEALAGGLVRSVHPQAELMDVARGIAREIADNTSAVSVSMTRAMMWRLPSGDHPMDAHRID
SRAIYRLSRGKDAAEGIASFLEKREPNYPGKVSEDMPDFYPWWDQPEYK

Specific function: Converts O-Succinylbenzoyl-CoA (Osb-CoA) To 1,4- Dihydroxy-2-Naphthoic Acid (Dhna). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=267, Percent_Identity=30.3370786516854, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI260274832, Length=203, Percent_Identity=33.9901477832512, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI45643119, Length=203, Percent_Identity=33.9901477832512, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI260275230, Length=203, Percent_Identity=33.9901477832512, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI31542718, Length=268, Percent_Identity=27.2388059701493, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4757966, Length=193, Percent_Identity=32.1243523316062, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI51538581, Length=193, Percent_Identity=32.1243523316062, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI25453481, Length=191, Percent_Identity=32.4607329842932, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI51538573, Length=191, Percent_Identity=32.4607329842932, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4757968, Length=262, Percent_Identity=27.4809160305344, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI49355787, Length=262, Percent_Identity=27.4809160305344, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4502327, Length=277, Percent_Identity=28.8808664259928, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI116235487, Length=190, Percent_Identity=30.5263157894737, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI70995211, Length=260, Percent_Identity=30.3846153846154, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221307494, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI221136756, Length=268, Percent_Identity=25.7462686567164, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221136753, Length=268, Percent_Identity=25.7462686567164, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=178, Percent_Identity=29.2134831460674, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI37594469, Length=159, Percent_Identity=25.7861635220126, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI37594471, Length=159, Percent_Identity=25.7861635220126, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI68989263, Length=192, Percent_Identity=30.2083333333333, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=29.1828793774319, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=31.0861423220974, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=31.6793893129771, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787659, Length=269, Percent_Identity=29.368029739777, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788682, Length=201, Percent_Identity=29.3532338308458, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082183, Length=277, Percent_Identity=24.187725631769, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790281, Length=196, Percent_Identity=30.1020408163265, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=268, Percent_Identity=30.5970149253731, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17549921, Length=234, Percent_Identity=32.0512820512821, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25145438, Length=258, Percent_Identity=30.2325581395349, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540714, Length=210, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=265, Percent_Identity=27.1698113207547, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=268, Percent_Identity=25.7462686567164, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=213, Percent_Identity=30.0469483568075, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=220, Percent_Identity=24.0909090909091, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24653139, Length=282, Percent_Identity=31.5602836879433, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20129971, Length=257, Percent_Identity=29.1828793774319, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24653477, Length=257, Percent_Identity=29.1828793774319, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24654903, Length=198, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357171, Length=207, Percent_Identity=29.951690821256, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19920382, Length=220, Percent_Identity=30, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 31764; Mature: 31633

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYTQILVDKADGIATVTLNRPEKMNAFTGTIMSEIITAMDDLDEDDDVRAVIFTGAGD
CCCHHEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
RAFCAGADLTPEGGGRVFSDPNEVDDLSDERVRDGGGRLTLRLFDSKKPLIAACNGAAVG
CEEECCCCCCCCCCCEECCCCCHHHCCCHHHHHCCCCEEEEEEECCCCCEEEECCCCEEC
VGSTMQLPMDIRLASDNARYGFVFARRGIVPEAASSWFLPKLVGISQALEWCYSGRVFDA
CCCEEECCEEEEEECCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHCCCEECH
QEALAGGLVRSVHPQAELMDVARGIAREIADNTSAVSVSMTRAMMWRLPSGDHPMDAHRI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCHHHC
DSRAIYRLSRGKDAAEGIASFLEKREPNYPGKVSEDMPDFYPWWDQPEYK
CHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDYTQILVDKADGIATVTLNRPEKMNAFTGTIMSEIITAMDDLDEDDDVRAVIFTGAGD
CCHHEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
RAFCAGADLTPEGGGRVFSDPNEVDDLSDERVRDGGGRLTLRLFDSKKPLIAACNGAAVG
CEEECCCCCCCCCCCEECCCCCHHHCCCHHHHHCCCCEEEEEEECCCCCEEEECCCCEEC
VGSTMQLPMDIRLASDNARYGFVFARRGIVPEAASSWFLPKLVGISQALEWCYSGRVFDA
CCCEEECCEEEEEECCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHCCCEECH
QEALAGGLVRSVHPQAELMDVARGIAREIADNTSAVSVSMTRAMMWRLPSGDHPMDAHRI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCHHHC
DSRAIYRLSRGKDAAEGIASFLEKREPNYPGKVSEDMPDFYPWWDQPEYK
CHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]