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The map label for this gene is glmS [H]

Identifier: 84625353

GI number: 84625353

Start: 4175151

End: 4176179

Strand: Reverse

Name: glmS [H]

Synonym: XOO_3696

Alternate gene names: 84625353

Gene position: 4176179-4175151 (Counterclockwise)

Preceding gene: 84625354

Following gene: 84625352

Centisome position: 84.53

GC content: 65.99

Gene sequence:

>1029_bases
ATGAGCCTTCCCACCGAAACCGATACCCTGATGTTCCGCGAAGCGGCGCAGACCGCCGATGTGGTTGCTGCACAGTTCGC
ACGTAACGCCGACACCATCGCTGCGCTTGCGCAGTCGCTGCGCGACAACCCGCCGCCGTTCGTGGTGACCTGCGCGCGCG
GCAGTTCCGATCATGCGGCCACCTATGCCAAGTATCTGTTCGAAACCCAGCTCGGCATCGTCACTGCGTCCGCGTCGCCG
TCGGTAGGCTCGGTGTATGCAGCGCCGCTGCACTTGCGTGGCGCGCTGTACATCGTGATTTCGCAATCGGGTAAAAGCCC
CGACCTGCTGCGCAATGCCGAAGCCGCCAAGGCCGCCGGCGCGCGCGTGGTGGCCCTGGTCAATGTGGAAGATTCGCCGC
TGGCGCAGTTGGCCGACGTGGTGATTCCGCTCGGCGCCGGCCCGGAAAAAAGCGTGGCCGCGACCAAGAGCTATCTCGCC
TCGCTGGCAGCAGTCCTGCAACTGGGCGCGATGTGGAAGAACGCCCCAGCGTTGCTGGCTGCGCTCGATGCATTGCCGCA
GCAGTTGCGCAACGCCTGGCAGGCCGATTGGTCCGCGCTCACCGCCGGCCTGGTGCCCGCACACAATCTGTTCGTGCTCG
GCCGCGGCCTGGGCCTGGGCGCGGCGCAGGAAGCGGCCTTGAAGTTCAAGGAAACCTGCGGCCTGCACGCCGAAGCCTAC
AGCTCGGCCGAGGTCAAACACGGCCCGATGGCCCTGGTAGGGCCGGGCTTCCCGGTGCTAGTGTTCGAGCAGCCTGATGA
AACCGGTGCCGGCACCCGCGCATTGGCCGAAGAATTCCGCGCGCGGGGTGCGCAGGTGTGGTTGGCCGCGTCCAGTGGCG
ATTTGCCGCTGGCAGAGGCCGCGCATCCGGCGTGTGCGCCGCTGCTGACCGTGCAGAGCTTCTATCGTGCGATCAATGCA
CTGGCGCTGCAGCGCGGCAACAATCCTGATCTTCCGCCGCACTTGAACAAGGTTACGGAAACCGTTTGA

Upstream 100 bases:

>100_bases
AGAACCGTGGCTTCGTGCCGCAACTGGTGGTGCGCGGCTCCACCGCGCCGGCGCCTGCGTCCACCGGCAAACCCCTTCCC
CCGAATCCGCCTGAGCCACG

Downstream 100 bases:

>100_bases
ACATGGATGCTTCCCGCACTCAGGCATTGTGCAATGCGCGTGTACTCACCGATGACGGCCTGCAGGACGGCCTGGTCGTG
GTGCTGGCTGGCACGCAGAT

Product: glucosamine-fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSLPTETDTLMFREAAQTADVVAAQFARNADTIAALAQSLRDNPPPFVVTCARGSSDHAATYAKYLFETQLGIVTASASP
SVGSVYAAPLHLRGALYIVISQSGKSPDLLRNAEAAKAAGARVVALVNVEDSPLAQLADVVIPLGAGPEKSVAATKSYLA
SLAAVLQLGAMWKNAPALLAALDALPQQLRNAWQADWSALTAGLVPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
SSAEVKHGPMALVGPGFPVLVFEQPDETGAGTRALAEEFRARGAQVWLAASSGDLPLAEAAHPACAPLLTVQSFYRAINA
LALQRGNNPDLPPHLNKVTETV

Sequences:

>Translated_342_residues
MSLPTETDTLMFREAAQTADVVAAQFARNADTIAALAQSLRDNPPPFVVTCARGSSDHAATYAKYLFETQLGIVTASASP
SVGSVYAAPLHLRGALYIVISQSGKSPDLLRNAEAAKAAGARVVALVNVEDSPLAQLADVVIPLGAGPEKSVAATKSYLA
SLAAVLQLGAMWKNAPALLAALDALPQQLRNAWQADWSALTAGLVPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
SSAEVKHGPMALVGPGFPVLVFEQPDETGAGTRALAEEFRARGAQVWLAASSGDLPLAEAAHPACAPLLTVQSFYRAINA
LALQRGNNPDLPPHLNKVTETV
>Mature_341_residues
SLPTETDTLMFREAAQTADVVAAQFARNADTIAALAQSLRDNPPPFVVTCARGSSDHAATYAKYLFETQLGIVTASASPS
VGSVYAAPLHLRGALYIVISQSGKSPDLLRNAEAAKAAGARVVALVNVEDSPLAQLADVVIPLGAGPEKSVAATKSYLAS
LAAVLQLGAMWKNAPALLAALDALPQQLRNAWQADWSALTAGLVPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAYS
SAEVKHGPMALVGPGFPVLVFEQPDETGAGTRALAEEFRARGAQVWLAASSGDLPLAEAAHPACAPLLTVQSFYRAINAL
ALQRGNNPDLPPHLNKVTETV

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=336, Percent_Identity=26.1904761904762, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI205277386, Length=311, Percent_Identity=24.7588424437299, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1790167, Length=329, Percent_Identity=29.483282674772, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17532899, Length=323, Percent_Identity=27.8637770897833, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17532897, Length=323, Percent_Identity=27.8637770897833, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17539970, Length=314, Percent_Identity=27.7070063694268, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322745, Length=314, Percent_Identity=25.1592356687898, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323731, Length=231, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357745, Length=359, Percent_Identity=24.7910863509749, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35541; Mature: 35410

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPTETDTLMFREAAQTADVVAAQFARNADTIAALAQSLRDNPPPFVVTCARGSSDHAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
TYAKYLFETQLGIVTASASPSVGSVYAAPLHLRGALYIVISQSGKSPDLLRNAEAAKAAG
HHHHHHHHHHHCEEEECCCCCCCCEEECCEEECCEEEEEEECCCCCCHHHHCCHHHHHCC
ARVVALVNVEDSPLAQLADVVIPLGAGPEKSVAATKSYLASLAAVLQLGAMWKNAPALLA
CEEEEEEECCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALDALPQQLRNAWQADWSALTAGLVPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHC
SSAEVKHGPMALVGPGFPVLVFEQPDETGAGTRALAEEFRARGAQVWLAASSGDLPLAEA
CCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHC
AHPACAPLLTVQSFYRAINALALQRGNNPDLPPHLNKVTETV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SLPTETDTLMFREAAQTADVVAAQFARNADTIAALAQSLRDNPPPFVVTCARGSSDHAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
TYAKYLFETQLGIVTASASPSVGSVYAAPLHLRGALYIVISQSGKSPDLLRNAEAAKAAG
HHHHHHHHHHHCEEEECCCCCCCCEEECCEEECCEEEEEEECCCCCCHHHHCCHHHHHCC
ARVVALVNVEDSPLAQLADVVIPLGAGPEKSVAATKSYLASLAAVLQLGAMWKNAPALLA
CEEEEEEECCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALDALPQQLRNAWQADWSALTAGLVPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHC
SSAEVKHGPMALVGPGFPVLVFEQPDETGAGTRALAEEFRARGAQVWLAASSGDLPLAEA
CCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHC
AHPACAPLLTVQSFYRAINALALQRGNNPDLPPHLNKVTETV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]