Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 84625352

GI number: 84625352

Start: 4173994

End: 4175148

Strand: Reverse

Name: nagA [H]

Synonym: XOO_3695

Alternate gene names: 84625352

Gene position: 4175148-4173994 (Counterclockwise)

Preceding gene: 84625353

Following gene: 84625346

Centisome position: 84.51

GC content: 67.19

Gene sequence:

>1155_bases
ATGGATGCTTCCCGCACTCAGGCATTGTGCAATGCGCGTGTACTCACCGATGACGGCCTGCAGGACGGCCTGGTCGTGGT
GCTGGCTGGCACGCAGATCCAGGCGATTGTGCCGGCCGATGATGCACGCGTTGCGCAGGCCGCCACGCGCGTGGATCTGG
GTGGCGCCACCTTGTTGCCAGGCTTTATCGACATCCAGGTCAACGGCGGCGGTGGCGTATTGTTCAACAACGCACGCGAC
CCGCAGGCGCTGGCGACCATCGCCGCCGCGCATCGTCGTTTCGGCACCACCGGCATGCTGCCGACCTTGATCAGCGATAC
CGCGCAGGTGATGGCCGAAGCGATCGAGGCCACCCGCGCAGCCATCGCGCAAGGCGTGCCCGGCGTGCTCGGCATCCATC
TGGAAGGCCCGTACCTGAGCCCTGCACGCAAGGGCACGCATGACGAACACAAGTTCCGGCTGCCGGACGCGCACGAAATT
GCCGTCGACACATCGCTGGACAACGGCGTCACCTTGATCACGCTCGCACCCGAGCGCGTGCCGCTGGACGATATCCGTGC
CTTCGTTGCCGGCGGCGCGATCGTGTTCGCTGGCCACACCGCGGCGACTTACGAGCAGGCACGCGACGGCATCGCTGCCG
GGGTGAGCGGCTTCACGCACGTGTACAACGCGATGTCGCAACTGGCTGGCCGCGAACCCAATGCAGTCGGCGCAGCGCTG
GAAGACCCCAACGTGTGGTGCGGCGTCATCGTCGATGGCGTGCATGTGCACCCGGCCAGCCTGCGCGTGGCGCTCGCGGC
CAAGCCACGCGGCAAGCTGTTGCTGGTCACCGACGCCATGCCCATGGTCGGCAGCGACAGCCCCGGCTTCGACCTGTACG
GCGAAACCATCACCGCCTTGGATGGCGTGGTGCGCAATGCCGACGGCGCACTGGCCGGTTCGGCATTGGACATGGCCACC
GCCGTGCGCAACAGCGTGCGCTGGCTCGGTGTGGACCTGGCCGAAGCCGCGCGCATGGCCTCGACGTATCCGGCGCAATG
TATCGGCCTTGGCGAACGTCTCGGCCGCATTGCGCCAGGCTACCAGGCCGACCTAGTGCTGGTGGATGCCGACGTGCAGG
TGCTGGGCACCTGGATCGCTGGGCAGCGCGACTAA

Upstream 100 bases:

>100_bases
TGCAGAGCTTCTATCGTGCGATCAATGCACTGGCGCTGCAGCGCGGCAACAATCCTGATCTTCCGCCGCACTTGAACAAG
GTTACGGAAACCGTTTGAAC

Downstream 100 bases:

>100_bases
GAGCGGCTAACAACACGACTGCGCCCACCTGACAGCTGCTCGCTATGTTGTGTTAGCCGCTCTAAATCCGAAGGACGGAC
AGCTGCGCGCGCTGGCAGGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MDASRTQALCNARVLTDDGLQDGLVVVLAGTQIQAIVPADDARVAQAATRVDLGGATLLPGFIDIQVNGGGGVLFNNARD
PQALATIAAAHRRFGTTGMLPTLISDTAQVMAEAIEATRAAIAQGVPGVLGIHLEGPYLSPARKGTHDEHKFRLPDAHEI
AVDTSLDNGVTLITLAPERVPLDDIRAFVAGGAIVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
EDPNVWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSDSPGFDLYGETITALDGVVRNADGALAGSALDMAT
AVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPGYQADLVLVDADVQVLGTWIAGQRD

Sequences:

>Translated_384_residues
MDASRTQALCNARVLTDDGLQDGLVVVLAGTQIQAIVPADDARVAQAATRVDLGGATLLPGFIDIQVNGGGGVLFNNARD
PQALATIAAAHRRFGTTGMLPTLISDTAQVMAEAIEATRAAIAQGVPGVLGIHLEGPYLSPARKGTHDEHKFRLPDAHEI
AVDTSLDNGVTLITLAPERVPLDDIRAFVAGGAIVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
EDPNVWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSDSPGFDLYGETITALDGVVRNADGALAGSALDMAT
AVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPGYQADLVLVDADVQVLGTWIAGQRD
>Mature_384_residues
MDASRTQALCNARVLTDDGLQDGLVVVLAGTQIQAIVPADDARVAQAATRVDLGGATLLPGFIDIQVNGGGGVLFNNARD
PQALATIAAAHRRFGTTGMLPTLISDTAQVMAEAIEATRAAIAQGVPGVLGIHLEGPYLSPARKGTHDEHKFRLPDAHEI
AVDTSLDNGVTLITLAPERVPLDDIRAFVAGGAIVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
EDPNVWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSDSPGFDLYGETITALDGVVRNADGALAGSALDMAT
AVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPGYQADLVLVDADVQVLGTWIAGQRD

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=390, Percent_Identity=33.0769230769231, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI224922791, Length=389, Percent_Identity=33.1619537275064, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1786892, Length=381, Percent_Identity=38.5826771653543, Blast_Score=251, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17553768, Length=356, Percent_Identity=31.4606741573034, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19920392, Length=347, Percent_Identity=33.7175792507205, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI281361140, Length=362, Percent_Identity=33.7016574585635, Blast_Score=175, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39709; Mature: 39709

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASRTQALCNARVLTDDGLQDGLVVVLAGTQIQAIVPADDARVAQAATRVDLGGATLLP
CCCHHHHHHHCCEEEECCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHEECCCCEECC
GFIDIQVNGGGGVLFNNARDPQALATIAAAHRRFGTTGMLPTLISDTAQVMAEAIEATRA
CEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIAQGVPGVLGIHLEGPYLSPARKGTHDEHKFRLPDAHEIAVDTSLDNGVTLITLAPERV
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCEEEEEECCCCC
PLDDIRAFVAGGAIVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
CHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
EDPNVWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSDSPGFDLYGETITAL
CCCCEEEEEEEECEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
DGVVRNADGALAGSALDMATAVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPG
HHHHHCCCCCCCCHHHHHHHHHHHCHHEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCCC
YQADLVLVDADVQVLGTWIAGQRD
CCEEEEEEECCCEEEEEECCCCCC
>Mature Secondary Structure
MDASRTQALCNARVLTDDGLQDGLVVVLAGTQIQAIVPADDARVAQAATRVDLGGATLLP
CCCHHHHHHHCCEEEECCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHEECCCCEECC
GFIDIQVNGGGGVLFNNARDPQALATIAAAHRRFGTTGMLPTLISDTAQVMAEAIEATRA
CEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIAQGVPGVLGIHLEGPYLSPARKGTHDEHKFRLPDAHEIAVDTSLDNGVTLITLAPERV
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCEEEEEECCCCC
PLDDIRAFVAGGAIVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
CHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
EDPNVWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSDSPGFDLYGETITAL
CCCCEEEEEEEECEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHH
DGVVRNADGALAGSALDMATAVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPG
HHHHHCCCCCCCCHHHHHHHHHHHCHHEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCCC
YQADLVLVDADVQVLGTWIAGQRD
CCEEEEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]