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The map label for this gene is thiL [H]

Identifier: 84625286

GI number: 84625286

Start: 4106224

End: 4107198

Strand: Reverse

Name: thiL [H]

Synonym: XOO_3629

Alternate gene names: 84625286

Gene position: 4107198-4106224 (Counterclockwise)

Preceding gene: 84625287

Following gene: 84625285

Centisome position: 83.14

GC content: 69.13

Gene sequence:

>975_bases
ATGCCCGAATTCGATCTAATCGCCCGGCTGCGCGTGCGCATTGCTGCGCGTGCCGATGTGCCGTTGGGCATTGGCGACGA
TGCGGCATTGCTGCATCCGCCGGCCGGTGAGCAGCTGGCGATCACCACCGATACGCTCAATGCCGGCGTGCATTTTCCGC
AGGAAACCCGCGCCGACGATCTGGGCTGGAAGACGCTGGCAGTCAATCTCTCTGACCTGGCGGCGATGGGCGCGCAACCG
CGTTGGTGCACCTTGTCGTTGTCGTTGCCGCACGACGATGCCGCATGGGTGGATCTATTCGCCGATGGCTTCTTCGCGCT
GGCCGATGCGCACGACATCGTGCTGGTCGGCGGCGACACCACCCGCGGGCCGCTCTCGTGCGCTGTAACGGCAATCGGTA
GCGTGCCGCCGAGCGCGGCGTTGCGGCGCGATGGTGCGCGCATTGGCGATGACGTGTGGGTCACCGGTGCGCCGGGTGAG
GCCGCCGCCGCGTTGGCGCTGTGGCAAGCCGGCCAGCTGGATGTGACCTGCGCGGCGGCTGACCCGTTGCACGAGCAGTG
GCGCAGCCGCTTGCTGCGTCCGCAGCCACGCGTACAGGCCGGGCTGCGTTTGCGCGGGCTTGCGCATGCCTGCGTGGACA
TTTCCGACGGGCTGCTGGCCGATCTGGGGCATCTGTGCGACCGCAGCGGTGTGGGCGCGCAACTGGCGCTGGCCGCGTTG
CCGGCAATGCCGCGCAGTGCCGGGACCAGCGTGGCGCAGTGCCCTGGCTGGCAACTCGGCGGTGGCGACGACTACGAGCT
GTGCTTCACCGCCGCGCCGCAGCATCGCGCTGCGGTGGCGCAGGCAATGGAGTTCGCCGAGGTGGCCGCGACGCGCATCG
GCCAGATTGTCGCCACGCCCGGCGTGGTGGTGCACGACGCCGACGGTAACCCTTGGCAACCGCTGCGGCGCGGCTATCAA
CACTTCGTTGGCTGA

Upstream 100 bases:

>100_bases
GCGCATCATTTGGTGGGCAGGCGGCAAGCAATCGTGCCGCACCTCGCAACGCCTGCTGCGACGAATCCCCAATGCACAAT
CTCCACTCCCGGCTCCTCAA

Downstream 100 bases:

>100_bases
GTCGCTCGTTATCAGGAATTCTTGAGCACCGGGTCCCGGTGCTTAGGGCAATCCCGAATCCCGGCCCTTGAACCATACCG
TACCGTCTGGTGCGTTCGCG

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPEFDLIARLRVRIAARADVPLGIGDDAALLHPPAGEQLAITTDTLNAGVHFPQETRADDLGWKTLAVNLSDLAAMGAQP
RWCTLSLSLPHDDAAWVDLFADGFFALADAHDIVLVGGDTTRGPLSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGE
AAAALALWQAGQLDVTCAAADPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLADLGHLCDRSGVGAQLALAAL
PAMPRSAGTSVAQCPGWQLGGGDDYELCFTAAPQHRAAVAQAMEFAEVAATRIGQIVATPGVVVHDADGNPWQPLRRGYQ
HFVG

Sequences:

>Translated_324_residues
MPEFDLIARLRVRIAARADVPLGIGDDAALLHPPAGEQLAITTDTLNAGVHFPQETRADDLGWKTLAVNLSDLAAMGAQP
RWCTLSLSLPHDDAAWVDLFADGFFALADAHDIVLVGGDTTRGPLSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGE
AAAALALWQAGQLDVTCAAADPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLADLGHLCDRSGVGAQLALAAL
PAMPRSAGTSVAQCPGWQLGGGDDYELCFTAAPQHRAAVAQAMEFAEVAATRIGQIVATPGVVVHDADGNPWQPLRRGYQ
HFVG
>Mature_323_residues
PEFDLIARLRVRIAARADVPLGIGDDAALLHPPAGEQLAITTDTLNAGVHFPQETRADDLGWKTLAVNLSDLAAMGAQPR
WCTLSLSLPHDDAAWVDLFADGFFALADAHDIVLVGGDTTRGPLSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGEA
AAALALWQAGQLDVTCAAADPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLADLGHLCDRSGVGAQLALAALP
AMPRSAGTSVAQCPGWQLGGGDDYELCFTAAPQHRAAVAQAMEFAEVAATRIGQIVATPGVVVHDADGNPWQPLRRGYQH
FVG

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=322, Percent_Identity=47.2049689440994, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33945; Mature: 33814

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEFDLIARLRVRIAARADVPLGIGDDAALLHPPAGEQLAITTDTLNAGVHFPQETRADD
CCCHHHHHHHHHHEEEECCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCC
LGWKTLAVNLSDLAAMGAQPRWCTLSLSLPHDDAAWVDLFADGFFALADAHDIVLVGGDT
CCCEEEEEEHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEECCCEEEEECCCC
TRGPLSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGEAAAALALWQAGQLDVTCAAA
CCCCHHEEEEECCCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEECC
DPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLADLGHLCDRSGVGAQLALAAL
CHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHH
PAMPRSAGTSVAQCPGWQLGGGDDYELCFTAAPQHRAAVAQAMEFAEVAATRIGQIVATP
CCCCCCCCCCHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECC
GVVVHDADGNPWQPLRRGYQHFVG
CEEEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PEFDLIARLRVRIAARADVPLGIGDDAALLHPPAGEQLAITTDTLNAGVHFPQETRADD
CCHHHHHHHHHHEEEECCCCCCCCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCC
LGWKTLAVNLSDLAAMGAQPRWCTLSLSLPHDDAAWVDLFADGFFALADAHDIVLVGGDT
CCCEEEEEEHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEECCCEEEEECCCC
TRGPLSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGEAAAALALWQAGQLDVTCAAA
CCCCHHEEEEECCCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEECC
DPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLADLGHLCDRSGVGAQLALAAL
CHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHH
PAMPRSAGTSVAQCPGWQLGGGDDYELCFTAAPQHRAAVAQAMEFAEVAATRIGQIVATP
CCCCCCCCCCHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECC
GVVVHDADGNPWQPLRRGYQHFVG
CEEEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]