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The map label for this gene is ycgM [C]

Identifier: 84489007

GI number: 84489007

Start: 220395

End: 221165

Strand: Direct

Name: ycgM [C]

Synonym: Msp_0179

Alternate gene names: 84489007

Gene position: 220395-221165 (Clockwise)

Preceding gene: 84489006

Following gene: 84489008

Centisome position: 12.47

GC content: 29.44

Gene sequence:

>771_bases
ATGAAATATATTAGATATATGGCTTCCAACAAAGAACATGTTGGAATAATAAAAGATGATATTATATATGATTTAGATTA
TTCATGTATTATTGATGCAATAGCACATGAAGATGAAATAGATATAAATGAATCTACAACAACACATAGATTAGAGGAGG
TAGATGTACTACCACCAACAAATCCTTCTAAGATTGTTTGTGTAGGCCTAAATTATAAAGATCATGCTAAAGAATTAAAT
ATGGAACTTCCAGATGAACCTTTATTATTTATGAAACCATCAACTTCTGTTATATCAACAAATAGTGCTATTATCTATCC
AAGTACTACAAACATGCTTGACTTTGAAGGAGAACTTGGAATTGTAATATTAGAAAAAGTATCTCCATGTGATAATGGTA
CTTGTAATGTTGCATACACTATTGTTAATGATGTAACAGCAAGGGATCTTCAAAGTAAGGATGGGCAATGGACACGTTCA
AAAAGTTATGATACATTTTGTCCATGTGGACCAGTAGTTGTTACAGGTATAGATTCATCAAATCTTAATATAAAAACTAT
GGTTAATAATGATATAAAACAAGAATCAAATACAAAAAATATGATATTTTCTCCATTAGAATTAGTAAAATATATCTCAA
ATATAATGACATTAAATCCAGGAGATATAATTGCATCAGGAACACCACCTGGTGTGGGTCACTTGGATGTGGGAGATACT
GTTGTTGTTGAAATTGATGAAATGGGAAGTTTAGTTAATATTGTTAAATAA

Upstream 100 bases:

>100_bases
ACTATAAATAAATTACGTAAAATTGGTGCAAAGGATTTACTAGTACTACCAATTGAAAGAATATTAGAAAATAAATAGGA
TATTAACAACTACGATTAAT

Downstream 100 bases:

>100_bases
AAAAAAATTAAATATAGGGGTTATTTAATGGAAATTAAAGAGTATACATGTGATGTGTTAGTAATAGGTTCTGGCGGTGC
TGGATGTAAATGTGGAATTG

Product: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKYIRYMASNKEHVGIIKDDIIYDLDYSCIIDAIAHEDEIDINESTTTHRLEEVDVLPPTNPSKIVCVGLNYKDHAKELN
MELPDEPLLFMKPSTSVISTNSAIIYPSTTNMLDFEGELGIVILEKVSPCDNGTCNVAYTIVNDVTARDLQSKDGQWTRS
KSYDTFCPCGPVVVTGIDSSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVGHLDVGDT
VVVEIDEMGSLVNIVK

Sequences:

>Translated_256_residues
MKYIRYMASNKEHVGIIKDDIIYDLDYSCIIDAIAHEDEIDINESTTTHRLEEVDVLPPTNPSKIVCVGLNYKDHAKELN
MELPDEPLLFMKPSTSVISTNSAIIYPSTTNMLDFEGELGIVILEKVSPCDNGTCNVAYTIVNDVTARDLQSKDGQWTRS
KSYDTFCPCGPVVVTGIDSSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVGHLDVGDT
VVVEIDEMGSLVNIVK
>Mature_256_residues
MKYIRYMASNKEHVGIIKDDIIYDLDYSCIIDAIAHEDEIDINESTTTHRLEEVDVLPPTNPSKIVCVGLNYKDHAKELN
MELPDEPLLFMKPSTSVISTNSAIIYPSTTNMLDFEGELGIVILEKVSPCDNGTCNVAYTIVNDVTARDLQSKDGQWTRS
KSYDTFCPCGPVVVTGIDSSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVGHLDVGDT
VVVEIDEMGSLVNIVK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=221, Percent_Identity=38.9140271493213, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI40786394, Length=219, Percent_Identity=40.6392694063927, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI13654274, Length=196, Percent_Identity=36.734693877551, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI215422413, Length=186, Percent_Identity=37.6344086021505, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI66348062, Length=186, Percent_Identity=37.6344086021505, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1787428, Length=194, Percent_Identity=34.5360824742268, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17557057, Length=202, Percent_Identity=36.6336633663366, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=31.6964285714286, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28572127, Length=283, Percent_Identity=33.9222614840989, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=32.512315270936, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 28206; Mature: 28206

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIRYMASNKEHVGIIKDDIIYDLDYSCIIDAIAHEDEIDINESTTTHRLEEVDVLPPT
CCEEEEECCCCCEEEEEECCEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCC
NPSKIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAIIYPSTTNMLDFEGELG
CCCEEEEEECCCHHHHHHCCCCCCCCCEEEECCCCCEEECCCEEEEECCCCEEEECCCEE
IVILEKVSPCDNGTCNVAYTIVNDVTARDLQSKDGQWTRSKSYDTFCPCGPVVVTGIDSS
EEEEEECCCCCCCCCEEEEEEECCCHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCC
NLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVGHLDVGDT
CCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHEECCCCCEEECCCCCCCCEECCCCE
VVVEIDEMGSLVNIVK
EEEEEHHCCCCHHHCC
>Mature Secondary Structure
MKYIRYMASNKEHVGIIKDDIIYDLDYSCIIDAIAHEDEIDINESTTTHRLEEVDVLPPT
CCEEEEECCCCCEEEEEECCEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCC
NPSKIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAIIYPSTTNMLDFEGELG
CCCEEEEEECCCHHHHHHCCCCCCCCCEEEECCCCCEEECCCEEEEECCCCEEEECCCEE
IVILEKVSPCDNGTCNVAYTIVNDVTARDLQSKDGQWTRSKSYDTFCPCGPVVVTGIDSS
EEEEEECCCCCCCCCEEEEEEECCCHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCC
NLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGTPPGVGHLDVGDT
CCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHHEECCCCCEEECCCCCCCCEECCCCE
VVVEIDEMGSLVNIVK
EEEEEHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]