Click here to switch to the map view.

The map label for this gene is uvrC [H]

Identifier: 83720723

GI number: 83720723

Start: 1948111

End: 1950339

Strand: Direct

Name: uvrC [H]

Synonym: BTH_I1739

Alternate gene names: 83720723

Gene position: 1948111-1950339 (Clockwise)

Preceding gene: 83721329

Following gene: 83718440

Centisome position: 51.14

GC content: 69.63

Gene sequence:

>2229_bases
TTGAGCATGACATCCCCCGACGCATCCGAATCCCGTTTCGAACCCAAGCCGATCCTCGCCCAACTGCCGCACCTGCCCGG
CGTCTACCGATATTACGACGCGCAGGAAGCGGTGCTGTACGTCGGCAAGGCGCGCGACCTGAAAAAGCGCGTGTCGAGCT
ACTTCACGAAGACGCAGCTGTCGCCGCGCATCGCGATGATGGTCACGCGCATCGCGCGCATCGAGACCACGGTCACGCGC
TCGGAGGCCGAGGCGCTGCTGCTCGAGAACAACCTGATCAAGGCGCTCGCGCCGCGCTACAACATCCTGTTTCGCGACGA
CAAGTCGTATCCGTACCTGAAGCTCACGGGCCATCGGTTTCCGCGGATGGCGTACTACCGGGGCGCGGTCGACAAGAAGA
ACCAGTACTTCGGGCCGTTTCCGAGCGCATGGGCGGTGCGCGAGAGCATCCAGATCCTGCAGCGCGTGTTTCAGTTGCGC
ACCTGCGAGGACTCGGTGTTCAGCAACCGCACGCGTCCGTGCCTGCTGCACCAGATCGGCCGCTGCTCGGCGCCGTGCGT
CGGCGCGATCGGCGAGGAGGATTACGCGCGCGACGTCGACAACGCGTCGCGCTTCCTGCTCGGCCGGCAGGGCGAGGTGA
TGGGCGAGCTCGAGCGGAAGATGCATGCGTTCGCGGCCGAGCTGAAGTTCGAGCAGGCGGCGGCCGTGCGCAACCAGATG
AGCTCGCTTGCGAAGGTGCTGCATCAGCAGGCGATCGACGTCGGCGGCGACAGCGACGTCGACATCCTCGCCGTCGTCGC
GCAGGGCGGCCGGGTGTGCGTGAATCTCGCGATGGTGCGCGGCGGCCGGCATCTCGGCGACAAGGCGTATTTCCCGACGC
ATGTCGAGACCGCGCTCGCCCTCGCGGGCGGCGTCGACGCGCACGCCGGCGAAGGGGCGGGCGACGACGCGCGGGACGCG
GCGGAATCGCCCGCGCAAGCGCGGCTTGCGGGCGATGCGGCGGCAAATGGGGTGGCAAATGCGGCGGCCGCGGCGCGCGC
GGACGATCGCTCGGCGCAGCCCACGCGCGCGCGGGCCGAAGGCGATGTCGAGCGAAGCGCGGACGCGAGCGCCGGCGCGC
GGGGCGAGGCCGATGCGCGCGAAGCCGCCGCGCCGTCTGAGCCCGACAGCGTTACCGCCGCATCGCAGGACGCGGACGCC
GACGCCGCGCCGCTCGAAACCGAAGTGCTCGAAGCGTTCATCGCGCAGCACTATCTCGGCAACCGCGTGCCGCCGATTCT
CGTCGTGAGCCACGCGATCGCGAATCGCGAGCTGATCGATCTGCTCGTCGAACAGGCGGGGCACAAGGTCGCGCTCGTGC
GGCAGCCGCAGGGCCAGAAGCGCGCGTGGCTCGCGATGGCCGAGCAGAACGCGCGCCTCGCGCTCGCGCGGCTGTTGTCC
GAGCAGGGATCGCAGCAGGCGCGCGCTCGCTCGCTCGCCGACGTGCTCGGCTACGAGAGCGACGATCTCGCGCAGCTGCG
CATCGAGTGCTTCGACATCAGCCATACGATGGGCGAGGCGACGCAGGCGTCGTGCGTCGTCTATCACCATCACAAGATGC
AGTCGTCCGAGTACCGCCGCTACAACATCGCGGGAATCACGCCCGGCGACGACTACGCGGCGATGCGCCAGGTGCTCACG
CGTCGCTACGAGAAGATGGTCGAGGAGGCGGCCGCCGAGGCGTCGGCCGACGAAGCGGCCGGCATCGACGGCAACGCGGT
GCATGCGGCCGCGTCGGCCGGCCGGCTGCCGAACATCGTGCTGATCGACGGCGGCCGGGGCCAGGTCGAGATCGCGCGCC
AGGTGTTTTCCGAGCTTGGGCTGGATATCTCGATGCTCGTCGGCGTCGCGAAGGGCGAGGGGCGCAAGGTCGGGCTCGAG
ACGCTGATCTTCGCCGACGGCCGCGCGCCGCTCGAGTTGGGCAAGGAGAGCGCCGCGCTGATGCTCGTCGCGCAGATCCG
CGACGAGGCGCACCGTTTCGCGATCACCGGGATGCGTGCGAAGCGGGCGAAGACGAGGCAGACGTCGCGGCTCGAGGAGC
TCGAAGGCGTCGGCGCGAAGCGGCGGCAGCGGCTGCTCGCGCGTTTCGGCGGCTTGCGCGGCGTCGTTGCCGCGAGCGTC
GACGAACTCGCGAGCGTCGAGGGCATCTCCCGCGCGCTCGCCGAGCAGATCTATCGGCAACTCCACTGA

Upstream 100 bases:

>100_bases
CGCGGACGCGCGGCGGCGGCCGGGCCGCGTTCGCGCGCGGCGAATGCTCTACACTGGCGATTCTAAATGACCTTGTTCGC
GCGCGCCCCTCGCACCCGCA

Downstream 100 bases:

>100_bases
GCGCCGCTCCTTCGCCGCCCGGCCCTTCGCGGGCAAGCCGGGCGGCGCGGTCCGGGCCGCCCGGCTTGCTTGTGGCGGCG
CGGGCGACGCGGCACAATGG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 742; Mature: 741

Protein sequence:

>742_residues
MSMTSPDASESRFEPKPILAQLPHLPGVYRYYDAQEAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTR
SEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRFPRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLR
TCEDSVFSNRTRPCLLHQIGRCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQM
SSLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPTHVETALALAGGVDAHAGEGAGDDARDA
AESPAQARLAGDAAANGVANAAAAARADDRSAQPTRARAEGDVERSADASAGARGEADAREAAAPSEPDSVTAASQDADA
DAAPLETEVLEAFIAQHYLGNRVPPILVVSHAIANRELIDLLVEQAGHKVALVRQPQGQKRAWLAMAEQNARLALARLLS
EQGSQQARARSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNIAGITPGDDYAAMRQVLT
RRYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNIVLIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLE
TLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASV
DELASVEGISRALAEQIYRQLH

Sequences:

>Translated_742_residues
MSMTSPDASESRFEPKPILAQLPHLPGVYRYYDAQEAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTR
SEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRFPRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLR
TCEDSVFSNRTRPCLLHQIGRCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQM
SSLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPTHVETALALAGGVDAHAGEGAGDDARDA
AESPAQARLAGDAAANGVANAAAAARADDRSAQPTRARAEGDVERSADASAGARGEADAREAAAPSEPDSVTAASQDADA
DAAPLETEVLEAFIAQHYLGNRVPPILVVSHAIANRELIDLLVEQAGHKVALVRQPQGQKRAWLAMAEQNARLALARLLS
EQGSQQARARSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNIAGITPGDDYAAMRQVLT
RRYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNIVLIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLE
TLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASV
DELASVEGISRALAEQIYRQLH
>Mature_741_residues
SMTSPDASESRFEPKPILAQLPHLPGVYRYYDAQEAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTRS
EAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRFPRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLRT
CEDSVFSNRTRPCLLHQIGRCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQMS
SLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPTHVETALALAGGVDAHAGEGAGDDARDAA
ESPAQARLAGDAAANGVANAAAAARADDRSAQPTRARAEGDVERSADASAGARGEADAREAAAPSEPDSVTAASQDADAD
AAPLETEVLEAFIAQHYLGNRVPPILVVSHAIANRELIDLLVEQAGHKVALVRQPQGQKRAWLAMAEQNARLALARLLSE
QGSQQARARSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNIAGITPGDDYAAMRQVLTR
RYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNIVLIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLET
LIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASVD
ELASVEGISRALAEQIYRQLH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=282, Percent_Identity=46.8085106382979, Blast_Score=285, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 80439; Mature: 80308

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTSPDASESRFEPKPILAQLPHLPGVYRYYDAQEAVLYVGKARDLKKRVSSYFTKTQL
CCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHCCCCHHHEEECCHHHHHHHHHHHHHHHCC
SPRIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCC
PRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFSNRTRPCLLHQIG
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
RCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQM
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPTHVETALA
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHCCCCCCCCCCCCHHHHHHHH
LAGGVDAHAGEGAGDDARDAAESPAQARLAGDAAANGVANAAAAARADDRSAQPTRARAE
HHCCCCCCCCCCCCCCHHHHHCCCHHHHHCCHHHHCHHHHHHHHHCCCCCCCCCCHHHCC
GDVERSADASAGARGEADAREAAAPSEPDSVTAASQDADADAAPLETEVLEAFIAQHYLG
CCCHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
NRVPPILVVSHAIANRELIDLLVEQAGHKVALVRQPQGQKRAWLAMAEQNARLALARLLS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHH
EQGSQQARARSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRR
HCCHHHHHHHHHHHHHCCCCCCHHHHHHHHEEHHHHHCCCCCCEEEEEEHHHCCCCCCCE
YNIAGITPGDDYAAMRQVLTRRYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNIV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCEEE
LIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLETLIFADGRAPLELGKESAAL
EEECCCCHHHHHHHHHHHHCCCHHHHHEECCCCCCEECCEEEEEECCCCHHHHCCCHHHH
MLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
DELASVEGISRALAEQIYRQLH
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMTSPDASESRFEPKPILAQLPHLPGVYRYYDAQEAVLYVGKARDLKKRVSSYFTKTQL
CCCCCCCCCCCCCCCCHHHHCCCCCCHHHHCCCCHHHEEECCHHHHHHHHHHHHHHHCC
SPRIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCC
PRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFSNRTRPCLLHQIG
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
RCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQM
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPTHVETALA
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHCCCCCCCCCCCCHHHHHHHH
LAGGVDAHAGEGAGDDARDAAESPAQARLAGDAAANGVANAAAAARADDRSAQPTRARAE
HHCCCCCCCCCCCCCCHHHHHCCCHHHHHCCHHHHCHHHHHHHHHCCCCCCCCCCHHHCC
GDVERSADASAGARGEADAREAAAPSEPDSVTAASQDADADAAPLETEVLEAFIAQHYLG
CCCHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
NRVPPILVVSHAIANRELIDLLVEQAGHKVALVRQPQGQKRAWLAMAEQNARLALARLLS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHH
EQGSQQARARSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRR
HCCHHHHHHHHHHHHHCCCCCCHHHHHHHHEEHHHHHCCCCCCEEEEEEHHHCCCCCCCE
YNIAGITPGDDYAAMRQVLTRRYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNIV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCEEE
LIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLETLIFADGRAPLELGKESAAL
EEECCCCHHHHHHHHHHHHCCCHHHHHEECCCCCCEECCEEEEEECCCCHHHHCCCHHHH
MLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
DELASVEGISRALAEQIYRQLH
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA