Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 83718440

GI number: 83718440

Start: 1950436

End: 1951059

Strand: Direct

Name: pgsA [H]

Synonym: BTH_I1740

Alternate gene names: 83718440

Gene position: 1950436-1951059 (Clockwise)

Preceding gene: 83720723

Following gene: 83718807

Centisome position: 51.2

GC content: 62.98

Gene sequence:

>624_bases
ATGGCAAATCCTTCAACCGTGTCGCGTGCCATGCCGTTCAATTTCCCGATTTTCCTGACGTGGGTGCGAATCGTGCTGAT
TCCGCTCGTCGTCGGCGTGTTTTACCTGCCGGACACGATGCTGAGCGCCGACCATCGCAATTTGGCGGCGGCCGTGATCT
TCATTCTTGCCGCGCTGACCGATTGGTTCGACGGCTATCTCGCGCGGAAATGGAACCAGACGTCGGCGTTCGGCGCGTTT
CTCGATCCGGTCGCCGACAAGCTGATGGTGACGGCGGCGCTGCTGATGCTCGTGCAGCTCGCGCGTATCGACGCGGCGAT
CGCGCTCGTGATCGTCGGCCGCGAAATCGCGATCTCGGCGCTGCGCGAATGGATGGCGCAGATCGGCGCGTCGAAGAGCG
TCGCGGTGAATTCGCTGGGCAAGTTCAAGACCGCGTGCCAGATGGTCGCGATTCCGATGCTGCTCTTCTATGGTCGTCTG
CCGTTCGGCGGCGGCGTCGCGATCGACACGCGCGTGTGGGGCGAGTGGCTGATCTATCTCGCGGCCGTGCTGACGATCTG
GTCGATGCTTTACTACATGAAGCTCGCGTGGCCGCAGATTCGCGAGCGTGGCGGCGCGGCGTGA

Upstream 100 bases:

>100_bases
CTGAGCGCCGCTCCTTCGCCGCCCGGCCCTTCGCGGGCAAGCCGGGCGGCGCGGTCCGGGCCGCCCGGCTTGCTTGTGGC
GGCGCGGGCGACGCGGCACA

Downstream 100 bases:

>100_bases
GCGCGCCGCCGAATGCACGGCGAAACGCGAGCGGGATCGCGCGCCGATGAGGGCGATGACGCGGTCGAAGAAAAAGGGCG
CGAAAAACGCTTGACACACA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MANPSTVSRAMPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARKWNQTSAFGAF
LDPVADKLMVTAALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRL
PFGGGVAIDTRVWGEWLIYLAAVLTIWSMLYYMKLAWPQIRERGGAA

Sequences:

>Translated_207_residues
MANPSTVSRAMPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARKWNQTSAFGAF
LDPVADKLMVTAALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRL
PFGGGVAIDTRVWGEWLIYLAAVLTIWSMLYYMKLAWPQIRERGGAA
>Mature_206_residues
ANPSTVSRAMPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALTDWFDGYLARKWNQTSAFGAFL
DPVADKLMVTAALLMLVQLARIDAAIALVIVGREIAISALREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRLP
FGGGVAIDTRVWGEWLIYLAAVLTIWSMLYYMKLAWPQIRERGGAA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=195, Percent_Identity=47.1794871794872, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22844; Mature: 22712

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPSTVSRAMPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALT
CCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHH
DWFDGYLARKWNQTSAFGAFLDPVADKLMVTAALLMLVQLARIDAAIALVIVGREIAISA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRLPFGGGVAIDTRVWGEWLIYL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
AAVLTIWSMLYYMKLAWPQIRERGGAA
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ANPSTVSRAMPFNFPIFLTWVRIVLIPLVVGVFYLPDTMLSADHRNLAAAVIFILAALT
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHH
DWFDGYLARKWNQTSAFGAFLDPVADKLMVTAALLMLVQLARIDAAIALVIVGREIAISA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREWMAQIGASKSVAVNSLGKFKTACQMVAIPMLLFYGRLPFGGGVAIDTRVWGEWLIYL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
AAVLTIWSMLYYMKLAWPQIRERGGAA
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]