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The map label for this gene is cheW [H]

Identifier: 83593657

GI number: 83593657

Start: 2691896

End: 2693497

Strand: Direct

Name: cheW [H]

Synonym: Rru_A2322

Alternate gene names: 83593657

Gene position: 2691896-2693497 (Clockwise)

Preceding gene: 83593656

Following gene: 83593658

Centisome position: 61.84

GC content: 66.04

Gene sequence:

>1602_bases
ATGTCCGAAATCACGCAGGCGGCGCTGGACTCGGGCCCGGATCCGTCGCAGGTCACCGGTGGCGCGGCGGCCGGCGCCCT
CCAAGCCGGAAACGCCCGCCAATTCGTCATCTTCCATGTCGATAACGACTTGTTCGCCGTGCCTTTGTCGGAAGTTCAAG
AGATCATCCGCATGCCCGATGTGGTGTGCGTGCCCCTCAGCCCGGCGGCGCTGGAGGGATTGGCCAACCTGCGGGGATCG
GTCTTGCCGGTCATTCGACTGCGCCATGTCTTCGGCATGGCCCCGGTTGTCCATGACGACGCGACCCGGGTCGTGGTGCT
TGATCAGGGGCGGCCGGTGGGACTGGTGGTCGACCGGGTGGCCAATGTCGTCTCGGTCGAGGCCGATCATATCGAGCCGT
CGGGGGCGATCGGCGGCACGGTCGACACCGACTTGCTGACCGGCATGATCAAGGGCGATGGCGACCGGGCGATGGTGATG
ATTCTCGACGCCGCCAAAGTGGTGGCGCGCGAGTTCCAGGCGATTGGCTCCGCCCCCCTGGCGCCGTCCCTGGGCGAGGC
CGGGCGCGCCGAGGATGGCCGCGTCCAGGCCGCGACCGACGGCGATGACGAAAGCCAACTGGTCAGTTTCGAGGTGGCCG
GCCAGGAATACGCCCTGCCGATCGAGCGGGTGCAGGAGATCGTCCAGATCCCCGGCCTGATCACCGACGTCCCCAACACC
CCGGCCCATGTCTTGGGGGTGATGACGCTGCGCAACCGGCTGCTGCCGCTGGTCGGCCTGCGCGAGATGTTCGGCCTGCC
CACGCTCGCCCTAACCGAGACCAACAAGATCGTCGTGGTCTCGCTCGAGGGGGGCGCAGGGGGAAGCGGACGCTCGGTCG
GCGTGGTGATGGACAGCGTCAAGGAGGTCCTGCGGGTCGGCCACGCCCTGATCGATCCGATGCCGGCGCTGCTCGCCCGC
ACGGGAAACCTGGGCGAAATCGAAGCCATCTGCCGGCTGCAGGGCGGCAACCGGCTGGTGTCGATCCTGTCGGCCGACGC
GATGTTCAACAGCGACGAAATTCGCGCCGTGGCGGCGAATGCGCTGGGAGAGGAGGACGCGGTGGCCGACGAAGAGACCC
CTGGATACCTTGGCACGACCGATGACGAGGAGCAGTTCGTCGCCTTCCGGTTGATGAACGAGGAATATGGCGTGCCGATC
GATTCGGTTCAGGAAATCGTCCGGGTGCCCGAGGAACTGACCCGGGTGCCCAAAACCCCCGACTTCATCGAAGGCGTGGT
CAACCTGCGCGGCGTGGTGCTGCCGGTGGTCGATCAACGCCGCCGCTTCGGCCTGCCGGGGATGGAGCGCAACGACCGCC
AGCGGATCATGGTCTACACCATCCGGGGGGTGCGGACCGGCTTCATCGTTGATTCGGTGTCCGAGGTGATCCGCATCCCG
GCCTCGTTGATCGGCCCGGCTCCGGTTCTATCGGACGAGCAACAGCGCCTGATCCGTCGGGTGGCCAATATCGAGAAACA
AAAACGGATGATCCTGCTGCTCGATGTCGAACAGTTGCTCGATGGAAAGGAATTGGCCGTCGTCGGCTCGGTGATCCCCT
AA

Upstream 100 bases:

>100_bases
CGCCGAGGAACTGGCCGCCGCCATCGAGGAGATCGCCTCGCTCGCCGACGAATTGCAGGCTGGCGCCTGATCCCCGCCCT
TGAGGTGTAAGGAGGACCTA

Downstream 100 bases:

>100_bases
ATCAGGACCGCTTTGGCGAAGATTTCTTTAAAGCCGAGATTCTGATCTGCATTGACTGGGTTACAGCGGGAAAATCGCCG
ACACCGGCTATTTTTCCGCT

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MSEITQAALDSGPDPSQVTGGAAAGALQAGNARQFVIFHVDNDLFAVPLSEVQEIIRMPDVVCVPLSPAALEGLANLRGS
VLPVIRLRHVFGMAPVVHDDATRVVVLDQGRPVGLVVDRVANVVSVEADHIEPSGAIGGTVDTDLLTGMIKGDGDRAMVM
ILDAAKVVAREFQAIGSAPLAPSLGEAGRAEDGRVQAATDGDDESQLVSFEVAGQEYALPIERVQEIVQIPGLITDVPNT
PAHVLGVMTLRNRLLPLVGLREMFGLPTLALTETNKIVVVSLEGGAGGSGRSVGVVMDSVKEVLRVGHALIDPMPALLAR
TGNLGEIEAICRLQGGNRLVSILSADAMFNSDEIRAVAANALGEEDAVADEETPGYLGTTDDEEQFVAFRLMNEEYGVPI
DSVQEIVRVPEELTRVPKTPDFIEGVVNLRGVVLPVVDQRRRFGLPGMERNDRQRIMVYTIRGVRTGFIVDSVSEVIRIP
ASLIGPAPVLSDEQQRLIRRVANIEKQKRMILLLDVEQLLDGKELAVVGSVIP

Sequences:

>Translated_533_residues
MSEITQAALDSGPDPSQVTGGAAAGALQAGNARQFVIFHVDNDLFAVPLSEVQEIIRMPDVVCVPLSPAALEGLANLRGS
VLPVIRLRHVFGMAPVVHDDATRVVVLDQGRPVGLVVDRVANVVSVEADHIEPSGAIGGTVDTDLLTGMIKGDGDRAMVM
ILDAAKVVAREFQAIGSAPLAPSLGEAGRAEDGRVQAATDGDDESQLVSFEVAGQEYALPIERVQEIVQIPGLITDVPNT
PAHVLGVMTLRNRLLPLVGLREMFGLPTLALTETNKIVVVSLEGGAGGSGRSVGVVMDSVKEVLRVGHALIDPMPALLAR
TGNLGEIEAICRLQGGNRLVSILSADAMFNSDEIRAVAANALGEEDAVADEETPGYLGTTDDEEQFVAFRLMNEEYGVPI
DSVQEIVRVPEELTRVPKTPDFIEGVVNLRGVVLPVVDQRRRFGLPGMERNDRQRIMVYTIRGVRTGFIVDSVSEVIRIP
ASLIGPAPVLSDEQQRLIRRVANIEKQKRMILLLDVEQLLDGKELAVVGSVIP
>Mature_532_residues
SEITQAALDSGPDPSQVTGGAAAGALQAGNARQFVIFHVDNDLFAVPLSEVQEIIRMPDVVCVPLSPAALEGLANLRGSV
LPVIRLRHVFGMAPVVHDDATRVVVLDQGRPVGLVVDRVANVVSVEADHIEPSGAIGGTVDTDLLTGMIKGDGDRAMVMI
LDAAKVVAREFQAIGSAPLAPSLGEAGRAEDGRVQAATDGDDESQLVSFEVAGQEYALPIERVQEIVQIPGLITDVPNTP
AHVLGVMTLRNRLLPLVGLREMFGLPTLALTETNKIVVVSLEGGAGGSGRSVGVVMDSVKEVLRVGHALIDPMPALLART
GNLGEIEAICRLQGGNRLVSILSADAMFNSDEIRAVAANALGEEDAVADEETPGYLGTTDDEEQFVAFRLMNEEYGVPID
SVQEIVRVPEELTRVPKTPDFIEGVVNLRGVVLPVVDQRRRFGLPGMERNDRQRIMVYTIRGVRTGFIVDSVSEVIRIPA
SLIGPAPVLSDEQQRLIRRVANIEKQKRMILLLDVEQLLDGKELAVVGSVIP

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=151, Percent_Identity=37.7483443708609, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 56880; Mature: 56749

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEITQAALDSGPDPSQVTGGAAAGALQAGNARQFVIFHVDNDLFAVPLSEVQEIIRMPD
CCHHHHHHHCCCCCCCCCCCCHHHCCEECCCCCEEEEEEECCCEEECCHHHHHHHHCCCC
VVCVPLSPAALEGLANLRGSVLPVIRLRHVFGMAPVVHDDATRVVVLDQGRPVGLVVDRV
EEEECCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHH
ANVVSVEADHIEPSGAIGGTVDTDLLTGMIKGDGDRAMVMILDAAKVVAREFQAIGSAPL
HHHHEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCC
APSLGEAGRAEDGRVQAATDGDDESQLVSFEVAGQEYALPIERVQEIVQIPGLITDVPNT
CCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEECCCCC
PAHVLGVMTLRNRLLPLVGLREMFGLPTLALTETNKIVVVSLEGGAGGSGRSVGVVMDSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHH
KEVLRVGHALIDPMPALLARTGNLGEIEAICRLQGGNRLVSILSADAMFNSDEIRAVAAN
HHHHHHHHHHHCCHHHHHHCCCCCCCEEEHEEECCCCCEEEEEHHHHHCCCCHHHHHHHH
ALGEEDAVADEETPGYLGTTDDEEQFVAFRLMNEEYGVPIDSVQEIVRVPEELTRVPKTP
HCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHCCHHHHHCCCCH
DFIEGVVNLRGVVLPVVDQRRRFGLPGMERNDRQRIMVYTIRGVRTGFIVDSVSEVIRIP
HHHHHHHHHCCEEEECHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC
ASLIGPAPVLSDEQQRLIRRVANIEKQKRMILLLDVEQLLDGKELAVVGSVIP
HHHCCCCCCCCCHHHHHHHHHHCHHHHCCEEEEEEHHHHHCCCCEEEECCCCC
>Mature Secondary Structure 
SEITQAALDSGPDPSQVTGGAAAGALQAGNARQFVIFHVDNDLFAVPLSEVQEIIRMPD
CHHHHHHHCCCCCCCCCCCCHHHCCEECCCCCEEEEEEECCCEEECCHHHHHHHHCCCC
VVCVPLSPAALEGLANLRGSVLPVIRLRHVFGMAPVVHDDATRVVVLDQGRPVGLVVDRV
EEEECCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHH
ANVVSVEADHIEPSGAIGGTVDTDLLTGMIKGDGDRAMVMILDAAKVVAREFQAIGSAPL
HHHHEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCC
APSLGEAGRAEDGRVQAATDGDDESQLVSFEVAGQEYALPIERVQEIVQIPGLITDVPNT
CCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEECCCCC
PAHVLGVMTLRNRLLPLVGLREMFGLPTLALTETNKIVVVSLEGGAGGSGRSVGVVMDSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHH
KEVLRVGHALIDPMPALLARTGNLGEIEAICRLQGGNRLVSILSADAMFNSDEIRAVAAN
HHHHHHHHHHHCCHHHHHHCCCCCCCEEEHEEECCCCCEEEEEHHHHHCCCCHHHHHHHH
ALGEEDAVADEETPGYLGTTDDEEQFVAFRLMNEEYGVPIDSVQEIVRVPEELTRVPKTP
HCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHCCHHHHHCCCCH
DFIEGVVNLRGVVLPVVDQRRRFGLPGMERNDRQRIMVYTIRGVRTGFIVDSVSEVIRIP
HHHHHHHHHCCEEEECHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC
ASLIGPAPVLSDEQQRLIRRVANIEKQKRMILLLDVEQLLDGKELAVVGSVIP
HHHCCCCCCCCCHHHHHHHHHHCHHHHCCEEEEEEHHHHHCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]