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The map label for this gene is tlpC [H]

Identifier: 83593656

GI number: 83593656

Start: 2689937

End: 2691865

Strand: Direct

Name: tlpC [H]

Synonym: Rru_A2321

Alternate gene names: 83593656

Gene position: 2689937-2691865 (Clockwise)

Preceding gene: 83593655

Following gene: 83593657

Centisome position: 61.8

GC content: 65.22

Gene sequence:

>1929_bases
ATGGCTCTTGTCAAAAAAAATCAAGTTGGCGGAGCCGCATCCGCTAAAACGGCCACCACCGATGATGTCAGTGGTGGCGG
CCGGCTTCTCGCCGAGGCGCAAAAGCGCAAGGCGCGAACCTTTGCCCGCCAGCAAAAAGCGGCCGAGCGTGTCGCCGCCG
CCACCTCGCAGCTTGCCAGCGGCCTGGCCGAGGCCGCCTCGGCCGCCGAGGAATTGAGGAAGGCCTCCGAACAGATCGCC
TCGGGCGCCGAGGAGGCGGCCGGGGCCGCCCAGCAATCGATGAAGGCGGTCGGCCACGGCGCCGGACTGATCATCAAGGG
CAAGGAAAGCGCCGATTCCGCCCTGATCAAGACCGAAGCCCTTCAAACGATGATCTTCTCGATCTCGGCGCAGATCGGCA
ATTCGATCCAGGCGATCGGCCGGGCGGCCGAGCGTCAAACCAATTCGGTTCGCATGGTCGAGGAGCTGGAAAGCCAAGCG
GCCGCCATCTCGGAGGTGGTCAAGGCCGTCGCCCGCATCGCCGACCAGACCAACCTGCTGGCGCTCAATGCCGCGATCGA
GGCGGCCCGGGCCGGGCAGCACGGCAAGGGCTTCGCCGTGGTCGCCGACGAGGTGCGTACCCTGGCTGAAACCTCGGAAA
AAAGCGCCCGGGAAATCCAGGACCTGATCACCCAGATCCAGACCGACGTCAAGGCGATCGCCGAGGGTATCACCGCCTCG
GCCGCCACCGCCCGCAGGGAGGTGGAGAAAGGCGCGCAGATCAGCGTTCAGTTGGAGCGCATTCGCACGGACATGGTCGC
CGTCTCGGCCGGCTGCCGGGACATCGTCAAGGCCAATGAGGAATCGACCGCCGCCGTCAAGGAGGTGCAGAAAGGCTCCG
AACTGATCGCGGCGGCCGCCGAGGAGCAAAGCGCCGCCTGTCAGGAAACGCTTAAGACCATCGACCAGCAAACCGCCGCC
CTCGCGCAATCGGAACAAGCCTCGCAGGAACTGTCCGAACTGGCCGACGAACTGAAGAATTCCACGGACATCTCAAAGAG
CAGCGAAGAGGTCGCCTCGGCGGCCGAGGAACTGTCCTCGGCGGTCGAGGAAATCAACCGCGCCGCCACCCAGATCCAGG
TCGCCCTCGACCAGATCCAGAAGGGCGCCCAGCAGCAGGCGGCGGCGACCCAGCAAGCCTCGGCGGCGATCGCCCAGATC
GAACGCGGCGCCCAGGTCTCGGCCAATCGGGCGACGACCACGGTGGAAAAAAGCGAGACGACCGCCCAACTGCTCCTTTC
CGCCAGCGAGTTGATCAATGAAATGATCGCCGGCGTCTTGGACTCGGTCGAGGCCGGCAAGCGCAGCCGCGAGCAGATGA
CCGCCCTGGAACAGGTCAGCCGTCGGATCGACAAGATCGTCGACGCCATCACCACCGTATCGATCCAGACCAATATGCTG
GCGGTCAACGGGTCGGTCGAAGCCGCGCGGGCGGGTGAATTCGGCAAGGGCTTCGCCGTGGTTTCCACCGATATCCGCAA
TCTTGCCCGCGATTCGGCCGAGAACGCCGACCGTATCAAGGACACCATCAAGTCGATTCAGGACCAGATCGGCTCGGTCC
GTCGCGACCTCGACGAAATATCGGCCGCCGCCACCCTTGAGGGGGAAAAGAACAAGGCCATCACCGTGGATCTGGAAACC
ATTTCCCGCGACATCGATCAGGTGCTGATCGGCGGCCGGGAAATCCTGGCCAGCTCGGACGAGATCGTCCAGGTGGTCAA
GGAGGTGCAGACCGGCGTCGAACAGATCGCGGCGGCCGCCCAGCAGACCACCCGCGCCACCCTCGAAGCCGGAAACGCGG
CGCGAGAGCAGTCGCAGGGCGCCGAGGAACTGGCCGCCGCCATCGAGGAGATCGCCTCGCTCGCCGACGAATTGCAGGCT
GGCGCCTGA

Upstream 100 bases:

>100_bases
CTTAGAATAAAAACTTACCGTATGGCAACTATTCATTGAATTAATGCTATTGAATATCGATTCTCTAAGACATCCCGGAA
ATGAAATGAAGGGGAATGCT

Downstream 100 bases:

>100_bases
TCCCCGCCCTTGAGGTGTAAGGAGGACCTAATGTCCGAAATCACGCAGGCGGCGCTGGACTCGGGCCCGGATCCGTCGCA
GGTCACCGGTGGCGCGGCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MALVKKNQVGGAASAKTATTDDVSGGGRLLAEAQKRKARTFARQQKAAERVAAATSQLASGLAEAASAAEELRKASEQIA
SGAEEAAGAAQQSMKAVGHGAGLIIKGKESADSALIKTEALQTMIFSISAQIGNSIQAIGRAAERQTNSVRMVEELESQA
AAISEVVKAVARIADQTNLLALNAAIEAARAGQHGKGFAVVADEVRTLAETSEKSAREIQDLITQIQTDVKAIAEGITAS
AATARREVEKGAQISVQLERIRTDMVAVSAGCRDIVKANEESTAAVKEVQKGSELIAAAAEEQSAACQETLKTIDQQTAA
LAQSEQASQELSELADELKNSTDISKSSEEVASAAEELSSAVEEINRAATQIQVALDQIQKGAQQQAAATQQASAAIAQI
ERGAQVSANRATTTVEKSETTAQLLLSASELINEMIAGVLDSVEAGKRSREQMTALEQVSRRIDKIVDAITTVSIQTNML
AVNGSVEAARAGEFGKGFAVVSTDIRNLARDSAENADRIKDTIKSIQDQIGSVRRDLDEISAAATLEGEKNKAITVDLET
ISRDIDQVLIGGREILASSDEIVQVVKEVQTGVEQIAAAAQQTTRATLEAGNAAREQSQGAEELAAAIEEIASLADELQA
GA

Sequences:

>Translated_642_residues
MALVKKNQVGGAASAKTATTDDVSGGGRLLAEAQKRKARTFARQQKAAERVAAATSQLASGLAEAASAAEELRKASEQIA
SGAEEAAGAAQQSMKAVGHGAGLIIKGKESADSALIKTEALQTMIFSISAQIGNSIQAIGRAAERQTNSVRMVEELESQA
AAISEVVKAVARIADQTNLLALNAAIEAARAGQHGKGFAVVADEVRTLAETSEKSAREIQDLITQIQTDVKAIAEGITAS
AATARREVEKGAQISVQLERIRTDMVAVSAGCRDIVKANEESTAAVKEVQKGSELIAAAAEEQSAACQETLKTIDQQTAA
LAQSEQASQELSELADELKNSTDISKSSEEVASAAEELSSAVEEINRAATQIQVALDQIQKGAQQQAAATQQASAAIAQI
ERGAQVSANRATTTVEKSETTAQLLLSASELINEMIAGVLDSVEAGKRSREQMTALEQVSRRIDKIVDAITTVSIQTNML
AVNGSVEAARAGEFGKGFAVVSTDIRNLARDSAENADRIKDTIKSIQDQIGSVRRDLDEISAAATLEGEKNKAITVDLET
ISRDIDQVLIGGREILASSDEIVQVVKEVQTGVEQIAAAAQQTTRATLEAGNAAREQSQGAEELAAAIEEIASLADELQA
GA
>Mature_641_residues
ALVKKNQVGGAASAKTATTDDVSGGGRLLAEAQKRKARTFARQQKAAERVAAATSQLASGLAEAASAAEELRKASEQIAS
GAEEAAGAAQQSMKAVGHGAGLIIKGKESADSALIKTEALQTMIFSISAQIGNSIQAIGRAAERQTNSVRMVEELESQAA
AISEVVKAVARIADQTNLLALNAAIEAARAGQHGKGFAVVADEVRTLAETSEKSAREIQDLITQIQTDVKAIAEGITASA
ATARREVEKGAQISVQLERIRTDMVAVSAGCRDIVKANEESTAAVKEVQKGSELIAAAAEEQSAACQETLKTIDQQTAAL
AQSEQASQELSELADELKNSTDISKSSEEVASAAEELSSAVEEINRAATQIQVALDQIQKGAQQQAAATQQASAAIAQIE
RGAQVSANRATTTVEKSETTAQLLLSASELINEMIAGVLDSVEAGKRSREQMTALEQVSRRIDKIVDAITTVSIQTNMLA
VNGSVEAARAGEFGKGFAVVSTDIRNLARDSAENADRIKDTIKSIQDQIGSVRRDLDEISAAATLEGEKNKAITVDLETI
SRDIDQVLIGGREILASSDEIVQVVKEVQTGVEQIAAAAQQTTRATLEAGNAAREQSQGAEELAAAIEEIASLADELQAG
A

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=214, Percent_Identity=33.1775700934579, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI2367378, Length=166, Percent_Identity=34.9397590361446, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788195, Length=219, Percent_Identity=32.8767123287671, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788194, Length=71, Percent_Identity=52.112676056338, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789453, Length=80, Percent_Identity=47.5, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66974; Mature: 66843

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVKKNQVGGAASAKTATTDDVSGGGRLLAEAQKRKARTFARQQKAAERVAAATSQLAS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAEAASAAEELRKASEQIASGAEEAAGAAQQSMKAVGHGAGLIIKGKESADSALIKTEA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
LQTMIFSISAQIGNSIQAIGRAAERQTNSVRMVEELESQAAAISEVVKAVARIADQTNLL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALNAAIEAARAGQHGKGFAVVADEVRTLAETSEKSAREIQDLITQIQTDVKAIAEGITAS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATARREVEKGAQISVQLERIRTDMVAVSAGCRDIVKANEESTAAVKEVQKGSELIAAAA
HHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EEQSAACQETLKTIDQQTAALAQSEQASQELSELADELKNSTDISKSSEEVASAAEELSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AVEEINRAATQIQVALDQIQKGAQQQAAATQQASAAIAQIERGAQVSANRATTTVEKSET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TAQLLLSASELINEMIAGVLDSVEAGKRSREQMTALEQVSRRIDKIVDAITTVSIQTNML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
AVNGSVEAARAGEFGKGFAVVSTDIRNLARDSAENADRIKDTIKSIQDQIGSVRRDLDEI
EECCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAATLEGEKNKAITVDLETISRDIDQVLIGGREILASSDEIVQVVKEVQTGVEQIAAAA
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QQTTRATLEAGNAAREQSQGAEELAAAIEEIASLADELQAGA
HHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALVKKNQVGGAASAKTATTDDVSGGGRLLAEAQKRKARTFARQQKAAERVAAATSQLAS
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAEAASAAEELRKASEQIASGAEEAAGAAQQSMKAVGHGAGLIIKGKESADSALIKTEA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
LQTMIFSISAQIGNSIQAIGRAAERQTNSVRMVEELESQAAAISEVVKAVARIADQTNLL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALNAAIEAARAGQHGKGFAVVADEVRTLAETSEKSAREIQDLITQIQTDVKAIAEGITAS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATARREVEKGAQISVQLERIRTDMVAVSAGCRDIVKANEESTAAVKEVQKGSELIAAAA
HHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EEQSAACQETLKTIDQQTAALAQSEQASQELSELADELKNSTDISKSSEEVASAAEELSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AVEEINRAATQIQVALDQIQKGAQQQAAATQQASAAIAQIERGAQVSANRATTTVEKSET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TAQLLLSASELINEMIAGVLDSVEAGKRSREQMTALEQVSRRIDKIVDAITTVSIQTNML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
AVNGSVEAARAGEFGKGFAVVSTDIRNLARDSAENADRIKDTIKSIQDQIGSVRRDLDEI
EECCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAATLEGEKNKAITVDLETISRDIDQVLIGGREILASSDEIVQVVKEVQTGVEQIAAAA
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QQTTRATLEAGNAAREQSQGAEELAAAIEEIASLADELQAGA
HHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]