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The map label for this gene is spoIVB [H]

Identifier: 83590349

GI number: 83590349

Start: 1550436

End: 1551758

Strand: Reverse

Name: spoIVB [H]

Synonym: Moth_1506

Alternate gene names: 83590349

Gene position: 1551758-1550436 (Counterclockwise)

Preceding gene: 83590350

Following gene: 83590348

Centisome position: 59.03

GC content: 57.22

Gene sequence:

>1323_bases
ATGCCCTTGAAACGCTTGGGGCACCGGGTCCTGGGCCTGGTGCTGGCGGCAATGTTACTCTACGGTGGCCTGGCTCCGCC
GGTACGCAATTTTTTTGCCCTCCCCTGGCAGCAGCGCCTGCCGGCAGCAGCGCCAATTTCCCTGCCCTGGGAACTGCCGC
CGGGTCTGGCCCGCCAGGTCGAAGTGAAGGTTAATAGCGGGGACTGGAGCAGAGCCACTACCGGCGATTTCCCCCGGTGG
TTACAGCTACAATTAAAATTGTTCGGCTTTATTCCATTAAAGAATATTACCATTCAGCTGGTACAACCGGTCGATGTTTC
TCCCGGCGGCCAGGCTATAGGGGTCTTCTTGAAGACCGAAGGCGTCCAGGTAGTAGGCCAGGCGGCGATTGTAGACGAGA
GGGGTAACAAGGTTTACCTGGCCCGGCAGGCAGGCCTGGAAACAGGCGACGCCATCATCGCCATTGACGGTCAGAAGGTA
ACCAGCGACCAGGAAGTGGCCAACCTGATCAATGCCGCCGGGCAGGCCAATCGCCAGGCCAGGATCACCGTTAAAAGGGA
AGGCCACTTGTTGACCCTGAACATCCACCCTCGCTACTGCCAGGAAACAGGGCGCTACCGGATTGGCGTCTATGTCCGGG
ACAGTACGGCCGGCGTCGGCACCCTGACCTTTTACGATCAAAACAAGGGCGTTTTCGGTGCCCTGGGCCACGTAGTTACC
GGCAGTGACGGCCAGACGGCCATGGATATCAGCGGCGGCAGGATAGTAGCGGCGGCCATCCAGGGTATCCACCAGGGCTA
CCGGGGGCAACCGGGAGAAAAGCTGGGCGTTTTTCTGGAAAACGGCCAATTTAGCGGTACTATACAGAAGAATACTATTG
TTGGCATATTTGGAACGATAACCGGCAAGCTTCCCGGTAATAAAGAGATACCAGTAGCCCTGGCCGATACTGTCCACCCC
GGACCGGCAGAAATCCTGACGGTTATCGAAGGAGAAAAGGTCGAAAGTTTCCAGGTGGAAATCGAACGGGTCATGCCCCA
CCAGCGGGCCAGCGGCAAGGGCCTGGTCCTTAGGATTACCGACCCCAGGTTACTGGCCGTAACCGGAGGCATTATCCAGG
GTATGAGCGGGAGTCCCATTATTCAAGACGGCCAACTGGCCGGTGCCGTAACCCACGTCTTTATCAACGACCCGACCCGG
GGTTACGGGGTGCTGGCGGAATGGATGCTCCAGGAGACAGAACTTGTTCCTAAAGATAAAGCCAGGGGTGCTACTGTCGA
AACCCCTGGTTCTTTCCTTTTTGTGGTATTTTGTGTAGGATAA

Upstream 100 bases:

>100_bases
GGTCGCTTTTGACAGCATAAAAGCCACGGCTTGAGGTTATTTTATGTTTAGAACAAAAAACAAAAACACGTTAAAAAGCG
GTAGGCAAGGGAGGAAGGTG

Downstream 100 bases:

>100_bases
CCAAAACTTTTGCCTCTTTATGCGAATGGAAGGATTATCCCCTGGTGACGTCGAAACACTATCTGGCAAATTAATGACAG
GGTTTTTGCAGGAGGCGGGA

Product: SpoIVB peptidase

Products: NA

Alternate protein names: Sporulation factor IV B protease; Stage IV sporulation protein B [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MPLKRLGHRVLGLVLAAMLLYGGLAPPVRNFFALPWQQRLPAAAPISLPWELPPGLARQVEVKVNSGDWSRATTGDFPRW
LQLQLKLFGFIPLKNITIQLVQPVDVSPGGQAIGVFLKTEGVQVVGQAAIVDERGNKVYLARQAGLETGDAIIAIDGQKV
TSDQEVANLINAAGQANRQARITVKREGHLLTLNIHPRYCQETGRYRIGVYVRDSTAGVGTLTFYDQNKGVFGALGHVVT
GSDGQTAMDISGGRIVAAAIQGIHQGYRGQPGEKLGVFLENGQFSGTIQKNTIVGIFGTITGKLPGNKEIPVALADTVHP
GPAEILTVIEGEKVESFQVEIERVMPHQRASGKGLVLRITDPRLLAVTGGIIQGMSGSPIIQDGQLAGAVTHVFINDPTR
GYGVLAEWMLQETELVPKDKARGATVETPGSFLFVVFCVG

Sequences:

>Translated_440_residues
MPLKRLGHRVLGLVLAAMLLYGGLAPPVRNFFALPWQQRLPAAAPISLPWELPPGLARQVEVKVNSGDWSRATTGDFPRW
LQLQLKLFGFIPLKNITIQLVQPVDVSPGGQAIGVFLKTEGVQVVGQAAIVDERGNKVYLARQAGLETGDAIIAIDGQKV
TSDQEVANLINAAGQANRQARITVKREGHLLTLNIHPRYCQETGRYRIGVYVRDSTAGVGTLTFYDQNKGVFGALGHVVT
GSDGQTAMDISGGRIVAAAIQGIHQGYRGQPGEKLGVFLENGQFSGTIQKNTIVGIFGTITGKLPGNKEIPVALADTVHP
GPAEILTVIEGEKVESFQVEIERVMPHQRASGKGLVLRITDPRLLAVTGGIIQGMSGSPIIQDGQLAGAVTHVFINDPTR
GYGVLAEWMLQETELVPKDKARGATVETPGSFLFVVFCVG
>Mature_439_residues
PLKRLGHRVLGLVLAAMLLYGGLAPPVRNFFALPWQQRLPAAAPISLPWELPPGLARQVEVKVNSGDWSRATTGDFPRWL
QLQLKLFGFIPLKNITIQLVQPVDVSPGGQAIGVFLKTEGVQVVGQAAIVDERGNKVYLARQAGLETGDAIIAIDGQKVT
SDQEVANLINAAGQANRQARITVKREGHLLTLNIHPRYCQETGRYRIGVYVRDSTAGVGTLTFYDQNKGVFGALGHVVTG
SDGQTAMDISGGRIVAAAIQGIHQGYRGQPGEKLGVFLENGQFSGTIQKNTIVGIFGTITGKLPGNKEIPVALADTVHPG
PAEILTVIEGEKVESFQVEIERVMPHQRASGKGLVLRITDPRLLAVTGGIIQGMSGSPIIQDGQLAGAVTHVFINDPTRG
YGVLAEWMLQETELVPKDKARGATVETPGSFLFVVFCVG

Specific function: Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by c

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Forespore intermembrane space [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase S55 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR014219
- InterPro:   IPR008763 [H]

Pfam domain/function: PF00595 PDZ; PF05580 Peptidase_S55 [H]

EC number: =3.4.21.116 [H]

Molecular weight: Translated: 47105; Mature: 46974

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKRLGHRVLGLVLAAMLLYGGLAPPVRNFFALPWQQRLPAAAPISLPWELPPGLARQV
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCEEE
EVKVNSGDWSRATTGDFPRWLQLQLKLFGFIPLKNITIQLVQPVDVSPGGQAIGVFLKTE
EEEECCCCCCCCCCCCCCHHHHEEEEEEEEEEECCEEEEEEECCCCCCCCCEEEEEEEEC
GVQVVGQAAIVDERGNKVYLARQAGLETGDAIIAIDGQKVTSDQEVANLINAAGQANRQA
CEEEEEEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEE
RITVKREGHLLTLNIHPRYCQETGRYRIGVYVRDSTAGVGTLTFYDQNKGVFGALGHVVT
EEEEEECCEEEEEECCHHHHHHCCCEEEEEEEEECCCCEEEEEEEECCCCEEEECCEEEE
GSDGQTAMDISGGRIVAAAIQGIHQGYRGQPGEKLGVFLENGQFSGTIQKNTIVGIFGTI
CCCCCEEEEECCCEEEHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEEECCEEEEEEEEE
TGKLPGNKEIPVALADTVHPGPAEILTVIEGEKVESFQVEIERVMPHQRASGKGLVLRIT
EECCCCCCCCCEEEECCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEC
DPRLLAVTGGIIQGMSGSPIIQDGQLAGAVTHVFINDPTRGYGVLAEWMLQETELVPKDK
CCEEEEEECHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
ARGATVETPGSFLFVVFCVG
CCCCEEECCCCEEEEEEEEC
>Mature Secondary Structure 
PLKRLGHRVLGLVLAAMLLYGGLAPPVRNFFALPWQQRLPAAAPISLPWELPPGLARQV
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCEEE
EVKVNSGDWSRATTGDFPRWLQLQLKLFGFIPLKNITIQLVQPVDVSPGGQAIGVFLKTE
EEEECCCCCCCCCCCCCCHHHHEEEEEEEEEEECCEEEEEEECCCCCCCCCEEEEEEEEC
GVQVVGQAAIVDERGNKVYLARQAGLETGDAIIAIDGQKVTSDQEVANLINAAGQANRQA
CEEEEEEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEE
RITVKREGHLLTLNIHPRYCQETGRYRIGVYVRDSTAGVGTLTFYDQNKGVFGALGHVVT
EEEEEECCEEEEEECCHHHHHHCCCEEEEEEEEECCCCEEEEEEEECCCCEEEECCEEEE
GSDGQTAMDISGGRIVAAAIQGIHQGYRGQPGEKLGVFLENGQFSGTIQKNTIVGIFGTI
CCCCCEEEEECCCEEEHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEEECCEEEEEEEEE
TGKLPGNKEIPVALADTVHPGPAEILTVIEGEKVESFQVEIERVMPHQRASGKGLVLRIT
EECCCCCCCCCEEEECCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEC
DPRLLAVTGGIIQGMSGSPIIQDGQLAGAVTHVFINDPTRGYGVLAEWMLQETELVPKDK
CCEEEEEECHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
ARGATVETPGSFLFVVFCVG
CCCCEEECCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2106508; 8969508; 9384377; 11741860 [H]