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The map label for this gene is spo0A

Identifier: 83590348

GI number: 83590348

Start: 1549556

End: 1550326

Strand: Reverse

Name: spo0A

Synonym: Moth_1505

Alternate gene names: 83590348

Gene position: 1550326-1549556 (Counterclockwise)

Preceding gene: 83590349

Following gene: 83590347

Centisome position: 58.98

GC content: 50.19

Gene sequence:

>771_bases
ATGGAGGCCATCAAGGTGCTTATTGCCGATGATAATCGGGAATTTTGCGAGGTACTGGAGGAATACTTCAACGAACAAGA
GGATTTCGTCCTATCAGGGGTAGCCCATAACGGCCAGGAAACCCTGGAACTTATCCAGGAACAAGAGCCGGATATTGTTA
TACTGGATATTATTATGCCCCACCTGGACGGTATCGGGGTGTTGGAAAAATTGCAGGTTTTAAATTTCGAGCCGCGACCC
AAGATTGTTATCCTCACCGCCCTGGGTCAGGAGAGTATGACCATGCGGTCGGTCGAACTGGGGGCTGATTACTACATATT
AAAACCCTTCGACCTGGAAGTGCTGGGAAACAGATTACGGCAACTGGCCAACGGCCATCCCCTGCCGACGGCGCCGTCTC
AGGTTAGCCGGGCCGGTCGTAATATGGATGTCGAGGTAACCAAGATTATCCATCAAATGGGCGTCCCTGCCCATATCAAA
GGTTATCAGTACCTGCGGGAGGCTATCTTGATGGTTATCGACGATGTCAGCCTCCTGGGAGCGGTAACGAAGGAACTCTA
TCCCCTTATCGCCCGCAAGTATATGACTACTCCCAGTCGCGTCGAACGCGCTATCCGGCATGCCATTGAACTCGCCTGGG
ACAGGGGCAATGTTGAGATGATGAATAAATTCTTCGGTTATACTATTAACGTTGAACGGGGTAAACCTACCAACTCGGAA
TTTATCGCCATGGTCGCCGATAAACTACGTATCGGGGCTAAGATAAACTAA

Upstream 100 bases:

>100_bases
TTGCCTCTTTATGCGAATGGAAGGATTATCCCCTGGTGACGTCGAAACACTATCTGGCAAATTAATGACAGGGTTTTTGC
AGGAGGCGGGATGAAATAAA

Downstream 100 bases:

>100_bases
AAACAGGAGGTTAGAGGGGGAAACTGGCGTGAGTGCCAGTTTCTTCTTGCGATTCCGCGAAGACCCGCGAGGATGACGCC
TCCCACCAGAGCCCATACCG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MEAIKVLIADDNREFCEVLEEYFNEQEDFVLSGVAHNGQETLELIQEQEPDIVILDIIMPHLDGIGVLEKLQVLNFEPRP
KIVILTALGQESMTMRSVELGADYYILKPFDLEVLGNRLRQLANGHPLPTAPSQVSRAGRNMDVEVTKIIHQMGVPAHIK
GYQYLREAILMVIDDVSLLGAVTKELYPLIARKYMTTPSRVERAIRHAIELAWDRGNVEMMNKFFGYTINVERGKPTNSE
FIAMVADKLRIGAKIN

Sequences:

>Translated_256_residues
MEAIKVLIADDNREFCEVLEEYFNEQEDFVLSGVAHNGQETLELIQEQEPDIVILDIIMPHLDGIGVLEKLQVLNFEPRP
KIVILTALGQESMTMRSVELGADYYILKPFDLEVLGNRLRQLANGHPLPTAPSQVSRAGRNMDVEVTKIIHQMGVPAHIK
GYQYLREAILMVIDDVSLLGAVTKELYPLIARKYMTTPSRVERAIRHAIELAWDRGNVEMMNKFFGYTINVERGKPTNSE
FIAMVADKLRIGAKIN
>Mature_256_residues
MEAIKVLIADDNREFCEVLEEYFNEQEDFVLSGVAHNGQETLELIQEQEPDIVILDIIMPHLDGIGVLEKLQVLNFEPRP
KIVILTALGQESMTMRSVELGADYYILKPFDLEVLGNRLRQLANGHPLPTAPSQVSRAGRNMDVEVTKIIHQMGVPAHIK
GYQYLREAILMVIDDVSLLGAVTKELYPLIARKYMTTPSRVERAIRHAIELAWDRGNVEMMNKFFGYTINVERGKPTNSE
FIAMVADKLRIGAKIN

Specific function: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the ex

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1789809, Length=135, Percent_Identity=34.0740740740741, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788192, Length=110, Percent_Identity=32.7272727272727, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=33.6206896551724, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=30.1587301587302, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082052, Length=121, Percent_Identity=38.8429752066116, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790860, Length=165, Percent_Identity=28.4848484848485, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP0A_MOOTA (P52941)

Other databases:

- EMBL:   CP000232
- EMBL:   U09983
- PIR:   S60881
- RefSeq:   YP_430357.1
- ProteinModelPortal:   P52941
- STRING:   P52941
- GeneID:   3831732
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1505
- NMPDR:   fig|264732.9.peg.1509
- eggNOG:   COG0784
- HOGENOM:   HBG304664
- OMA:   AHIKGYL
- ProtClustDB:   CLSK2527078
- BioCyc:   MTHE264732:MOTH_1505-MONOMER
- GO:   GO:0005737
- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR014879
- InterPro:   IPR012052
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF002937
- ProDom:   PD010908
- SMART:   SM00448
- TIGRFAMs:   TIGR02875

Pfam domain/function: PF00072 Response_reg; PF08769 Spo0A_C; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 28988; Mature: 28988

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIKVLIADDNREFCEVLEEYFNEQEDFVLSGVAHNGQETLELIQEQEPDIVILDIIMP
CCCEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEHHH
HLDGIGVLEKLQVLNFEPRPKIVILTALGQESMTMRSVELGADYYILKPFDLEVLGNRLR
CCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHH
QLANGHPLPTAPSQVSRAGRNMDVEVTKIIHQMGVPAHIKGYQYLREAILMVIDDVSLLG
HHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVTKELYPLIARKYMTTPSRVERAIRHAIELAWDRGNVEMMNKFFGYTINVERGKPTNSE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCCCHH
FIAMVADKLRIGAKIN
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEAIKVLIADDNREFCEVLEEYFNEQEDFVLSGVAHNGQETLELIQEQEPDIVILDIIMP
CCCEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEHHH
HLDGIGVLEKLQVLNFEPRPKIVILTALGQESMTMRSVELGADYYILKPFDLEVLGNRLR
CCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHH
QLANGHPLPTAPSQVSRAGRNMDVEVTKIIHQMGVPAHIKGYQYLREAILMVIDDVSLLG
HHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVTKELYPLIARKYMTTPSRVERAIRHAIELAWDRGNVEMMNKFFGYTINVERGKPTNSE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEECCCCCCCHH
FIAMVADKLRIGAKIN
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7885226