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The map label for this gene is 83590331

Identifier: 83590331

GI number: 83590331

Start: 1536408

End: 1537370

Strand: Reverse

Name: 83590331

Synonym: Moth_1488

Alternate gene names: NA

Gene position: 1537370-1536408 (Counterclockwise)

Preceding gene: 83590332

Following gene: 83590330

Centisome position: 58.48

GC content: 60.12

Gene sequence:

>963_bases
ATGACCACTACCGGAGCCGGCCTGCCCCTGTTCCAGATCAGGCCTATGCTCGCCGTAATCAGCAGGCCCTTCGATTCCCC
GGATTTCTTGTATGAAATAAAATGGGACGGCTATCGTTGCCTGGCCTACCTTGAGGGACAAACCCTCCTCCAATCCCGCA
ACCTCCTGAACATTACACCCACCTTTCCCGAACTGGCCAGCCTCCACCAGCGGGTAAAAGGGCAACCGGCAGTACTGGAC
GGGGAGATTATCGTCCCCGGGAAGGATGGCAAGCCTTCCTTCAGCCTCCTCCAGGGGAGGGGCCGCCTGGGAGACCCCCT
TAAAGTAAGGCAGGCGGCCAGGCGCATGCCGGCCATCTTTGTCGCCTTTGACCTCCTTTATTACCAGGGCGAAAACATTA
TGCCGGAGCCCCTCCGCTGGCGCAAAGAAAGGCTTCAGGAGGCATTAGCGCCGGGGGAGAACCTGATTGTCTCCAGTTTT
ATTGAAAACTATGGTATGAAGTTCTATGAGGCCTGTGTTGGCCAGGGGCTGGAAGGAGTGATGGCCAAGGAACTGGACAG
CCCTTACCTCCCCGGTAAACGCTCACCCCGATGGCGCAAATTCAGGCACACCCGGGCGGGGGAGTTTATTATTGCCGGCT
ATGAACCGGGAGCCGGCGGGCGTCTCCTGGGGTCCCTCATCCTGGCGGAATGCCGGGAGGGGCAGCTGGTTTACCGCGGC
AAGGTGGGTACAGGCTTTGACCGGCAGGAGGAAAAGAAGTTGCTGGTAGAGTTGCAGCAGCTCCAGCCCGGGCCGCCGCC
TTTTAAGGAAAACATCCCGGAGCTAAGGAAGCCCCGGTGGGTGCAACCCCGGCTGGTTTGTACGGTGGAGTACCTGGAGC
TGACCCCGGACGGCCGCCTCCGTCACCCCACTTACCGCGGCCTGCGCTGGGATAAGGCTCCATGGGAATGCACCTCGACC
TGA

Upstream 100 bases:

>100_bases
TGGAGGCCCTGAAAGCCAGCATCGAACTGGCCAGGCAGGAAAAGGAGAAAGTTGCTGCCGACGTCGAGGACCGCAAGCCC
CGCCGCCGGCGCAAAACTTC

Downstream 100 bases:

>100_bases
AGAAGATTTATTACAAACAAAACCACGGTATTTTTGAATCTTTAAGAACCAATTTAATTATGGAACGTTATTTTAGAATC
GTTGCAAATCCTTGAATAAC

Product: ATP dependent DNA ligase, central

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTTTGAGLPLFQIRPMLAVISRPFDSPDFLYEIKWDGYRCLAYLEGQTLLQSRNLLNITPTFPELASLHQRVKGQPAVLD
GEIIVPGKDGKPSFSLLQGRGRLGDPLKVRQAARRMPAIFVAFDLLYYQGENIMPEPLRWRKERLQEALAPGENLIVSSF
IENYGMKFYEACVGQGLEGVMAKELDSPYLPGKRSPRWRKFRHTRAGEFIIAGYEPGAGGRLLGSLILAECREGQLVYRG
KVGTGFDRQEEKKLLVELQQLQPGPPPFKENIPELRKPRWVQPRLVCTVEYLELTPDGRLRHPTYRGLRWDKAPWECTST

Sequences:

>Translated_320_residues
MTTTGAGLPLFQIRPMLAVISRPFDSPDFLYEIKWDGYRCLAYLEGQTLLQSRNLLNITPTFPELASLHQRVKGQPAVLD
GEIIVPGKDGKPSFSLLQGRGRLGDPLKVRQAARRMPAIFVAFDLLYYQGENIMPEPLRWRKERLQEALAPGENLIVSSF
IENYGMKFYEACVGQGLEGVMAKELDSPYLPGKRSPRWRKFRHTRAGEFIIAGYEPGAGGRLLGSLILAECREGQLVYRG
KVGTGFDRQEEKKLLVELQQLQPGPPPFKENIPELRKPRWVQPRLVCTVEYLELTPDGRLRHPTYRGLRWDKAPWECTST
>Mature_319_residues
TTTGAGLPLFQIRPMLAVISRPFDSPDFLYEIKWDGYRCLAYLEGQTLLQSRNLLNITPTFPELASLHQRVKGQPAVLDG
EIIVPGKDGKPSFSLLQGRGRLGDPLKVRQAARRMPAIFVAFDLLYYQGENIMPEPLRWRKERLQEALAPGENLIVSSFI
ENYGMKFYEACVGQGLEGVMAKELDSPYLPGKRSPRWRKFRHTRAGEFIIAGYEPGAGGRLLGSLILAECREGQLVYRGK
VGTGFDRQEEKKLLVELQQLQPGPPPFKENIPELRKPRWVQPRLVCTVEYLELTPDGRLRHPTYRGLRWDKAPWECTST

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=364, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320038, Length=273, Percent_Identity=28.9377289377289, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 36368; Mature: 36236

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTGAGLPLFQIRPMLAVISRPFDSPDFLYEIKWDGYRCLAYLEGQTLLQSRNLLNITP
CCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCHHHHHCCCEEEECC
TFPELASLHQRVKGQPAVLDGEIIVPGKDGKPSFSLLQGRGRLGDPLKVRQAARRMPAIF
CCHHHHHHHHHHCCCCCEECCEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCHHH
VAFDLLYYQGENIMPEPLRWRKERLQEALAPGENLIVSSFIENYGMKFYEACVGQGLEGV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCHHHH
MAKELDSPYLPGKRSPRWRKFRHTRAGEFIIAGYEPGAGGRLLGSLILAECREGQLVYRG
HHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEC
KVGTGFDRQEEKKLLVELQQLQPGPPPFKENIPELRKPRWVQPRLVCTVEYLELTPDGRL
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCCCCCEEEEEEEEEEECCCCCC
RHPTYRGLRWDKAPWECTST
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTTGAGLPLFQIRPMLAVISRPFDSPDFLYEIKWDGYRCLAYLEGQTLLQSRNLLNITP
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCHHHHHCCCEEEECC
TFPELASLHQRVKGQPAVLDGEIIVPGKDGKPSFSLLQGRGRLGDPLKVRQAARRMPAIF
CCHHHHHHHHHHCCCCCEECCEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCHHH
VAFDLLYYQGENIMPEPLRWRKERLQEALAPGENLIVSSFIENYGMKFYEACVGQGLEGV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCHHHH
MAKELDSPYLPGKRSPRWRKFRHTRAGEFIIAGYEPGAGGRLLGSLILAECREGQLVYRG
HHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEC
KVGTGFDRQEEKKLLVELQQLQPGPPPFKENIPELRKPRWVQPRLVCTVEYLELTPDGRL
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCCCCCEEEEEEEEEEECCCCCC
RHPTYRGLRWDKAPWECTST
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]