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The map label for this gene is fruR [H]

Identifier: 82750400

GI number: 82750400

Start: 711571

End: 712332

Strand: Direct

Name: fruR [H]

Synonym: SAB0647

Alternate gene names: 82750400

Gene position: 711571-712332 (Clockwise)

Preceding gene: 82750399

Following gene: 82750401

Centisome position: 25.95

GC content: 31.89

Gene sequence:

>762_bases
ATGATAATTACAGAAAAAAGACACGAGTTAATATTAGAAGAACTTTCGCACAAAGATTTTTTGACTTTACAAGAATTAAT
AGATCGAACTGGCTGCAGTGCTTCAACAATACGAAGAGATTTATCTAAACTACAACAATTAGGGAAATTGCAACGTGTGC
ATGGTGGTGCAATGTTAAAAGAAAATCGTATGGTTGAGGCGAATTTAACTGAAAAATTAGCAACTAATCTTGATGAAAAG
AAATTGATTGCTAAAATAGCAGCTAATCAAATCAACGATAATGAATGCTTATTTATCGATGCTGGTTCATCTACATTGGA
GCTAATTAAATATATTCAAGCGAAAGATATCATTGTGGTAACCAATGGTTTAACACATGTAGAAGCTTTACTTAAAAAAG
GTATTAAAACAATTATGCTAGGTGGTCAAGTTAAAGAAAATACACTTGCTACGATTGGTTCAAGTGCCATGGAGATATTA
AGACGATATTGTTTCGATAAAGCTTTTATCGGGATGAATGGATTAGATATTGAACTTGGATTAACTACTCCCGATGAGCA
AGAGGCATTAGTTAAACAAACAGTAATGTCATTAGCCAATCAATCATTTGTACTTATAGATCATTCTAAGTTTAATAAAG
TATATTTTGCTCGTGTACCTTTGCTAGAAAGTACGACAATCATCACATCTGAAAAAGCATTAAATCAAGAATCGTTAAAA
GAATACCAACAAAAGTATCACTTTATAGGAGGGACTTTATGA

Upstream 100 bases:

>100_bases
ATTTTATCGTCACAATTTGATTGTTTGTGATTGTTTTTGGTAATTTATGATTGAAAAGTGAAAGCGTACTCATTATAATA
CAGAGTGAGATGGGGTGATG

Downstream 100 bases:

>100_bases
TTTATACAGTGACTTTCAATCCTTCAATTGACTATGTCATTTTTACGAATGATTTTAAAATTGATGGTTTGAACAGAGCA
ACAGCAACATATAAATTCGC

Product: transcriptional repressor of fructose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MIITEKRHELILEELSHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLKENRMVEANLTEKLATNLDEK
KLIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEIL
RRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTVMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESLK
EYQQKYHFIGGTL

Sequences:

>Translated_253_residues
MIITEKRHELILEELSHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLKENRMVEANLTEKLATNLDEK
KLIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEIL
RRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTVMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESLK
EYQQKYHFIGGTL
>Mature_253_residues
MIITEKRHELILEELSHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLKENRMVEANLTEKLATNLDEK
KLIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEIL
RRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTVMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESLK
EYQQKYHFIGGTL

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=32.9059829059829, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789519, Length=241, Percent_Identity=29.045643153527, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1788069, Length=206, Percent_Identity=32.5242718446602, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789829, Length=211, Percent_Identity=28.9099526066351, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790635, Length=243, Percent_Identity=30.8641975308642, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=29.5652173913043, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789059, Length=243, Percent_Identity=27.9835390946502, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787063, Length=242, Percent_Identity=29.7520661157025, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790753, Length=237, Percent_Identity=25.3164556962025, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082344, Length=209, Percent_Identity=25.3588516746411, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=28.82096069869, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28352; Mature: 28352

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITEKRHELILEELSHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLK
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEC
ENRMVEANLTEKLATNLDEKKLIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVV
CCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCEEEE
TNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEILRRYCFDKAFIGMNGLDIELG
ECCHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LTTPDEQEALVKQTVMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESLK
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCEEEECHHHCCHHHHH
EYQQKYHFIGGTL
HHHHHHHHCCCCC
>Mature Secondary Structure
MIITEKRHELILEELSHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLK
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEC
ENRMVEANLTEKLATNLDEKKLIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVV
CCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCEEEE
TNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEILRRYCFDKAFIGMNGLDIELG
ECCHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LTTPDEQEALVKQTVMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESLK
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCEEEECHHHCCHHHHH
EYQQKYHFIGGTL
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]