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The map label for this gene is lepB2 [H]

Identifier: 78778991

GI number: 78778991

Start: 569954

End: 570538

Strand: Reverse

Name: lepB2 [H]

Synonym: PMT9312_0606

Alternate gene names: 78778991

Gene position: 570538-569954 (Counterclockwise)

Preceding gene: 78778996

Following gene: 78778990

Centisome position: 33.38

GC content: 29.57

Gene sequence:

>585_bases
ATGTCTAGAACTGAAGAAAAAAGAAATTCAATAATAAAGGATTTAAAAAATCTTTTAATTTGGATATCTATTGCTTTAAT
TATACGATGGCAGGTTATAGAGCCAAGATGGATTCCATCCGGTTCAATGCTTCCAACTCTTCAAATACAAGATAAAATTC
TTGTTGAGAAAGTAACCCCTAAAATCACATCCAAATCAAATCTTTCAAAATTAAAGAATAAAATAGTTGTTTTTAATGTT
CCGGATCAATTAATTAATGCTGGTTATGAAGCAGATACTGCATTAATAAAAAGAGTAATTGGAATACCTGGAGATAAAGT
AGAAGTAAGAGACGGTTACCTTTACTTAAATGATATCGCTCAAGAAAATTACGTTTTTGACAAAAATATAAATTATTCTA
TAGGACCTTTTATTGTTCCAGAAAAGTCTTTATGGGTGATGGGAGATAACAGAAACAATAGTATGGACTCTCATATTTGG
GGGTTTTTACCCTATGAAAAGATTATTGGTAAAGCTATTTTTAGATATTGGCCTTTTAATAAAATTGGACCTATTCGGTT
CCCTACCCTTAATAATTTAGATTAA

Upstream 100 bases:

>100_bases
AAAGTTGTAAACTTCTAAGAAAATTTTTGCATTCAATAGATGATGTCATAATTTATATAAATGCTTTGGGATTTTTCCTT
ATAATTGAATTAAATAAAAC

Downstream 100 bases:

>100_bases
TGGGTACGTGATGTTGTAGGGTTTTTATATCTTGAAGTTGTAGAAATGTTTAATCCAGAATTTCTTGCTACTGAAAATAA
TGATCCAAATGATGAGAATG

Product: leader peptidase I

Products: NA

Alternate protein names: SPase I-2; Leader peptidase I-2 [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSRTEEKRNSIIKDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKVTPKITSKSNLSKLKNKIVVFNV
PDQLINAGYEADTALIKRVIGIPGDKVEVRDGYLYLNDIAQENYVFDKNINYSIGPFIVPEKSLWVMGDNRNNSMDSHIW
GFLPYEKIIGKAIFRYWPFNKIGPIRFPTLNNLD

Sequences:

>Translated_194_residues
MSRTEEKRNSIIKDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKVTPKITSKSNLSKLKNKIVVFNV
PDQLINAGYEADTALIKRVIGIPGDKVEVRDGYLYLNDIAQENYVFDKNINYSIGPFIVPEKSLWVMGDNRNNSMDSHIW
GFLPYEKIIGKAIFRYWPFNKIGPIRFPTLNNLD
>Mature_193_residues
SRTEEKRNSIIKDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKVTPKITSKSNLSKLKNKIVVFNVP
DQLINAGYEADTALIKRVIGIPGDKVEVRDGYLYLNDIAQENYVFDKNINYSIGPFIVPEKSLWVMGDNRNNSMDSHIWG
FLPYEKIIGKAIFRYWPFNKIGPIRFPTLNNLD

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22432; Mature: 22300

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTEEKRNSIIKDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKVTP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEECCCCCCCEEEEECHHHHHHHHCC
KITSKSNLSKLKNKIVVFNVPDQLINAGYEADTALIKRVIGIPGDKVEVRDGYLYLNDIA
CCCCCHHHHHHHCEEEEEECCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCEEEEECCC
QENYVFDKNINYSIGPFIVPEKSLWVMGDNRNNSMDSHIWGFLPYEKIIGKAIFRYWPFN
CCCEEECCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHEECCCHHHHHHHHHHHHCCCC
KIGPIRFPTLNNLD
CCCCEECCCCCCCC
>Mature Secondary Structure 
SRTEEKRNSIIKDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKVTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEECCCCCCCEEEEECHHHHHHHHCC
KITSKSNLSKLKNKIVVFNVPDQLINAGYEADTALIKRVIGIPGDKVEVRDGYLYLNDIA
CCCCCHHHHHHHCEEEEEECCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCEEEEECCC
QENYVFDKNINYSIGPFIVPEKSLWVMGDNRNNSMDSHIWGFLPYEKIIGKAIFRYWPFN
CCCEEECCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHEECCCHHHHHHHHHHHHCCCC
KIGPIRFPTLNNLD
CCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]