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The map label for this gene is clpB [H]

Identifier: 78778965

GI number: 78778965

Start: 538402

End: 540984

Strand: Reverse

Name: clpB [H]

Synonym: PMT9312_0580

Alternate gene names: 78778965

Gene position: 540984-538402 (Counterclockwise)

Preceding gene: 78778966

Following gene: 78778963

Centisome position: 31.65

GC content: 31.13

Gene sequence:

>2583_bases
ATGAAAATAGTTCCAAGCGAATTTTCAAATTCTGCTTGGAACTGTTTTATTTTTGCTAAAGAAATTGCTTATAAAAATCA
CCAACAAGACGTAGACTCTGACAATTTATTATTAGCTCTTATAAAACAAGACAACCTTACAAAAAAGATCTTAAAAAAAA
ATAATGTAAATATCAAAGAGTTTGAGAAAGAAATAATGTCTTCATTAAATTCGAAGGCGAAAATGAAAAATAAACAAGAT
AATTTATATATTGGTGATACTCTTTACAAAATATTTTTAAAAGCGAACGATATTAAAAATACTTTTGATGATGTAGTGAT
ATCAACAGAACACTTAGTTTACGGTTTCACTTATGATAATAAATATGGATTTCAAATTTTAAATCAAAAAGGTATTCCGG
AATTTCTTGAAACTATAAAGAAAATGAAGTCAGATCCAGCAGTAAAAAATGACTTTGGTACTTCTAATGAGTCTTTAGAT
AAATATGGCATTGATCTAACCCAATCAGCAAGGGATGGGATCTTAGATCCAGTTATTGGTAGGGATGAAGAAATTAGAAG
AACAATTCAAATATTGAGTAGAAGAACAAAAAATAATCCAGTTCTTATTGGAGAACCTGGGGTTGGCAAAACAGCCATAG
TGGAAGGGTTGGCTCAAAGAATTATTAATGGCGATGTACCTTCTGCACTACAAAATAGGCAACTAATTTCATTAGATATG
GGTTCACTTTTAGCTGGAGCAAAATATCGTGGAGAATTTGAAGAAAGAATAAAAAATGTCCTAAAGAAAGTCAAGGGATC
AGACGGTAAGATCATTCTTTTTATTGATGAAATTCATACAGTAGTTGGTGCAGGCGCCAGTGGTGGTTCTTTAGATGCAA
GCAACCTATTAAAACCAATGCTTGCAAGAGGAGAACTTAGATGCATTGGTGCTACAACTATTAATGAACACAAACAAAAT
ATAGAAAAAGATCCTGCTTTAGAACGAAGATTTCAGAAAATAAAAATTGATGCTCCTTCAATAGATGATACTGTATCAAT
ATTAAGAGGCTTGAGAGAAAGATACGAAGTTCATCATAGTGTGAGAATTTCTGATAATGCTTTGGTTGCAGCTGCCACCC
TTAGCGAAAGATATATTAACGATAGATTTCTTCCTGACAAAGCGATAGATCTAATCGATGAAGCAGCCTCAAGATTAAAT
ATGATCATAACTTCCAAACCTGAAGAAATTGATGAAATTGATAGAAAAGTTCTACAGTTTGAGATGGAAAAATTATCTTT
AAAAAGAGAAACAGATAATTTTTCTATAGAAAGATTAAACAAAATTAATAATGAACTTATATCACTTAAAGATAGACAGG
CAGAATTAGGCGATCAATGGAAAAAAGAAAAAGATGAAATTGATGAGATTAGCACCATAAAAGAAGAAATTGAATCCATT
CAATTACAAATAGACCAGGCAAAAAGGAGTTTCGACCTGAACAAAGCCGCAGAATTGGAATTTGGGACTTTAAATTCTTT
ACAAAAAAAATTGAAAGGAAAAAGTGAGTCTCTAGTTAATTCTCACAAAAAAGGAGAGACGAGTCTTTTAAGGCAAGAAG
TAACTTTTGATGATATTGCAGAAGTTGTCTCAAAGTGGACCTCTATTCCAGTACAGAACTTAAACCAGTCGGAAAAAAAT
AAGCTTTTAAGCCTTGAGTCGATCCTTAAAGAAAAAATTATTGGTCAAGATAGTGCAATTAGGGCAGTTGCAGATTCCAT
TAAGAGATCAAGGACTGGTCTAAATGATCCAAACAAGCCATTAGCTAGTTTCCTCTTTTTAGGTCCAACTGGAGTTGGAA
AAACAGAGCTTAGTAAAGTAACAGCAAAAATTATATTCGATTCAAATTCTTCAATTACAAGACTGGATATGTCTGAATAT
ATGGAAAAGCATTCAGTTAGCAAAATCATAGGTGCGCCTCCTGGATATTTAGGTTTCGAATCAGGCGGTCAACTAACTGA
AGCTGTGCGCAAAAATCCGTATTCATTAATACTTCTTGATGAAATAGAGAAAGCTCACAAAGATATCTTAGATATTCTCT
TACAGGTTCTTGATGATGGAATCATTACGGATGGTCAAGGTCGTACAATCAATTTCAAGAATTCAATCATTGTTCTTACA
AGCAATTTAGGAAGTCAATCAATAAATGATTTATCAGTTAGAAAAGAAGATACAAATGAAATTAAAAAAGTTGTAGATAC
TGAACTTAAAAAATTTTTCAAGCCTGAGTTTTTAAATCGACTTGATGAAATAGTTATTTTTAATAATTTAGAATTAAATG
ACATAAAAGAAATTTCAAAAATCCAGCTTCAAAATTTAGAAAACAGACTTAACAAAAAAAATTTAAACTTCAAAATTACC
GATGATGCAATTAACCAACTGGTCCAAAATAGTTTTGACAATGCCTATGGTGCAAGGCCTTTAAAAAGAATTATTCAGAA
ACAAATTGAGACAAAAATTGCAAACAATATATTGAATAATCATTACCTTAATAAAAAAGAGGTTAATATTTATCTGGTTA
ATGGAGAGATAATTGTTGATTAA

Upstream 100 bases:

>100_bases
CACAGAGGGGCTGGAATGGTAGGTAAAGTTATTGTTGAATAAATCTCTAATAGTTAAGTATTTTTAATACTTATTAGAGT
CATACCTAATATTTTGATTG

Downstream 100 bases:

>100_bases
ATATCTAAATTAAAGAATTTTATAAGACTTGAAATTTAACAACTTTAATCTAAGATTCGAACCACTCAGGAATCATCTCA
TAACTTGCTTTATTAGATTT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MKIVPSEFSNSAWNCFIFAKEIAYKNHQQDVDSDNLLLALIKQDNLTKKILKKNNVNIKEFEKEIMSSLNSKAKMKNKQD
NLYIGDTLYKIFLKANDIKNTFDDVVISTEHLVYGFTYDNKYGFQILNQKGIPEFLETIKKMKSDPAVKNDFGTSNESLD
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQNRQLISLDM
GSLLAGAKYRGEFEERIKNVLKKVKGSDGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKIDAPSIDDTVSILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MIITSKPEEIDEIDRKVLQFEMEKLSLKRETDNFSIERLNKINNELISLKDRQAELGDQWKKEKDEIDEISTIKEEIESI
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKGKSESLVNSHKKGETSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKN
KLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPNKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDTNEIKKVVDTELKKFFKPEFLNRLDEIVIFNNLELNDIKEISKIQLQNLENRLNKKNLNFKIT
DDAINQLVQNSFDNAYGARPLKRIIQKQIETKIANNILNNHYLNKKEVNIYLVNGEIIVD

Sequences:

>Translated_860_residues
MKIVPSEFSNSAWNCFIFAKEIAYKNHQQDVDSDNLLLALIKQDNLTKKILKKNNVNIKEFEKEIMSSLNSKAKMKNKQD
NLYIGDTLYKIFLKANDIKNTFDDVVISTEHLVYGFTYDNKYGFQILNQKGIPEFLETIKKMKSDPAVKNDFGTSNESLD
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQNRQLISLDM
GSLLAGAKYRGEFEERIKNVLKKVKGSDGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKIDAPSIDDTVSILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MIITSKPEEIDEIDRKVLQFEMEKLSLKRETDNFSIERLNKINNELISLKDRQAELGDQWKKEKDEIDEISTIKEEIESI
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKGKSESLVNSHKKGETSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKN
KLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPNKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDTNEIKKVVDTELKKFFKPEFLNRLDEIVIFNNLELNDIKEISKIQLQNLENRLNKKNLNFKIT
DDAINQLVQNSFDNAYGARPLKRIIQKQIETKIANNILNNHYLNKKEVNIYLVNGEIIVD
>Mature_860_residues
MKIVPSEFSNSAWNCFIFAKEIAYKNHQQDVDSDNLLLALIKQDNLTKKILKKNNVNIKEFEKEIMSSLNSKAKMKNKQD
NLYIGDTLYKIFLKANDIKNTFDDVVISTEHLVYGFTYDNKYGFQILNQKGIPEFLETIKKMKSDPAVKNDFGTSNESLD
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQNRQLISLDM
GSLLAGAKYRGEFEERIKNVLKKVKGSDGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKIDAPSIDDTVSILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MIITSKPEEIDEIDRKVLQFEMEKLSLKRETDNFSIERLNKINNELISLKDRQAELGDQWKKEKDEIDEISTIKEEIESI
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKGKSESLVNSHKKGETSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKN
KLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPNKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDTNEIKKVVDTELKKFFKPEFLNRLDEIVIFNNLELNDIKEISKIQLQNLENRLNKKNLNFKIT
DDAINQLVQNSFDNAYGARPLKRIIQKQIETKIANNILNNHYLNKKEVNIYLVNGEIIVD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=300, Percent_Identity=37, Blast_Score=196, Evalue=9e-50,
Organism=Escherichia coli, GI1788943, Length=839, Percent_Identity=49.5828367103695, Blast_Score=825, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=274, Percent_Identity=52.9197080291971, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=770, Percent_Identity=47.6623376623377, Blast_Score=719, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=869, Percent_Identity=39.1254315304948, Blast_Score=605, Evalue=1e-173,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97127; Mature: 97127

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVPSEFSNSAWNCFIFAKEIAYKNHQQDVDSDNLLLALIKQDNLTKKILKKNNVNIKE
CCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHH
FEKEIMSSLNSKAKMKNKQDNLYIGDTLYKIFLKANDIKNTFDDVVISTEHLVYGFTYDN
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCHHHHHHHHHEEEECEEEEEEEECC
KYGFQILNQKGIPEFLETIKKMKSDPAVKNDFGTSNESLDKYGIDLTQSARDGILDPVIG
CCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCC
RDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQNRQLISLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEEECH
GSLLAGAKYRGEFEERIKNVLKKVKGSDGKIILFIDEIHTVVGAGASGGSLDASNLLKPM
HHHHHCCHHCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCCCCCHHHHHHHH
LARGELRCIGATTINEHKQNIEKDPALERRFQKIKIDAPSIDDTVSILRGLRERYEVHHS
HHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
VRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLNMIITSKPEEIDEIDRKVLQF
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHH
EMEKLSLKRETDNFSIERLNKINNELISLKDRQAELGDQWKKEKDEIDEISTIKEEIESI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKGKSESLVNSHKKGETSLLRQEVTFDDIA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCHHHHH
EVVSKWTSIPVQNLNQSEKNKLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPNKP
HHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCH
LASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEYMEKHSVSKIIGAPPGYLGFE
HHHHHEECCCCCCHHHHHHHEEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
SGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEE
SNLGSQSINDLSVRKEDTNEIKKVVDTELKKFFKPEFLNRLDEIVIFNNLELNDIKEISK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHHHHHH
IQLQNLENRLNKKNLNFKITDDAINQLVQNSFDNAYGARPLKRIIQKQIETKIANNILNN
HHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HYLNKKEVNIYLVNGEIIVD
CCCCCEEEEEEEECCEEEEC
>Mature Secondary Structure
MKIVPSEFSNSAWNCFIFAKEIAYKNHQQDVDSDNLLLALIKQDNLTKKILKKNNVNIKE
CCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHH
FEKEIMSSLNSKAKMKNKQDNLYIGDTLYKIFLKANDIKNTFDDVVISTEHLVYGFTYDN
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCHHHHHHHHHEEEECEEEEEEEECC
KYGFQILNQKGIPEFLETIKKMKSDPAVKNDFGTSNESLDKYGIDLTQSARDGILDPVIG
CCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCCCCCCCC
RDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQNRQLISLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEEECH
GSLLAGAKYRGEFEERIKNVLKKVKGSDGKIILFIDEIHTVVGAGASGGSLDASNLLKPM
HHHHHCCHHCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCCCCCHHHHHHHH
LARGELRCIGATTINEHKQNIEKDPALERRFQKIKIDAPSIDDTVSILRGLRERYEVHHS
HHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
VRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLNMIITSKPEEIDEIDRKVLQF
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHH
EMEKLSLKRETDNFSIERLNKINNELISLKDRQAELGDQWKKEKDEIDEISTIKEEIESI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKGKSESLVNSHKKGETSLLRQEVTFDDIA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCHHHHH
EVVSKWTSIPVQNLNQSEKNKLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPNKP
HHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCH
LASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEYMEKHSVSKIIGAPPGYLGFE
HHHHHEECCCCCCHHHHHHHEEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
SGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEE
SNLGSQSINDLSVRKEDTNEIKKVVDTELKKFFKPEFLNRLDEIVIFNNLELNDIKEISK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHHHHHH
IQLQNLENRLNKKNLNFKITDDAINQLVQNSFDNAYGARPLKRIIQKQIETKIANNILNN
HHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HYLNKKEVNIYLVNGEIIVD
CCCCCEEEEEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]