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The map label for this gene is ntcA [H]

Identifier: 78778633

GI number: 78778633

Start: 239315

End: 240049

Strand: Direct

Name: ntcA [H]

Synonym: PMT9312_0248

Alternate gene names: 78778633

Gene position: 239315-240049 (Clockwise)

Preceding gene: 78778629

Following gene: 78778634

Centisome position: 14.0

GC content: 35.51

Gene sequence:

>735_bases
ATGATACCTTCTTCTCGAGGATTCAGTCGCTTTAATTCGCAACAATCCGGACAAAGTAAGATTAACTCTGTTGGAGAACG
TTTTCCAATTAATAGAACTTTAATGGAAGTAATTAGAGGTCTAGAGGGTGCAAGCACAGAAATGGTTGAGAGATCTAAAA
CAATATTTTTCCCTGGGGATCCTGCCGAGAGGGTTTATTTGATAAGGAGAGGAGCAGTAAGATTGTCAAGAGTTTATGAA
TCAGGTGAAGAGATAACTGTTGCTCTATTAAGAGAAAATAGTCTCTTTGGTGTTTTATCTCTTCTAACAGGCCATAGATC
TGATCGTTTTTATCATTCCATAGCATTCACAAGAGTTGAAATGATAACAGCACCTGCGAATTCTGTTTTAAGAGCAATAG
AGGAAGATGCATCAGTTGGACTATTATTGTTGCAGGGTCTTTCAAGTAGGATCTTACAAACAGAAACAATGATAGAAACT
CTTACTCACAGAGATATGTCTTCACGTTTAGTAAGTTTTTTAATGGTTCTTTGTAGAGACTTTGGAGTCGCAAGTGAAAA
AGGTATTACAATAGATTTAAGACTTTCACATCAAGCTATTGCTGAAGCTATTGGTTCAACAAGAGTAACGATTACAAGAT
TATTAGGCGATTTAAAGGATTCTGGGCTCCTTAATATTGAAAGAAAAAAGATTACAGTATTTGATCCAATCGCTCTTTCA
AAAAGATTTAATTGA

Upstream 100 bases:

>100_bases
AGATAATTCCATAGAAAAATGAATAAGAATTGAAAATTGTTACAGTTGATACAAGATATTTCATGGTGTCTTCTTAAGTT
TTTTAATAGTTAAGATATTT

Downstream 100 bases:

>100_bases
TTTATCATTCATTATGATGTAATGAATGTATGAAATAGTGTGGCCTGGATCTTAATTGTTTTTTTAATATTACTCGGAGG
ATTAATTGCACCATTTGGGG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MIPSSRGFSRFNSQQSGQSKINSVGERFPINRTLMEVIRGLEGASTEMVERSKTIFFPGDPAERVYLIRRGAVRLSRVYE
SGEEITVALLRENSLFGVLSLLTGHRSDRFYHSIAFTRVEMITAPANSVLRAIEEDASVGLLLLQGLSSRILQTETMIET
LTHRDMSSRLVSFLMVLCRDFGVASEKGITIDLRLSHQAIAEAIGSTRVTITRLLGDLKDSGLLNIERKKITVFDPIALS
KRFN

Sequences:

>Translated_244_residues
MIPSSRGFSRFNSQQSGQSKINSVGERFPINRTLMEVIRGLEGASTEMVERSKTIFFPGDPAERVYLIRRGAVRLSRVYE
SGEEITVALLRENSLFGVLSLLTGHRSDRFYHSIAFTRVEMITAPANSVLRAIEEDASVGLLLLQGLSSRILQTETMIET
LTHRDMSSRLVSFLMVLCRDFGVASEKGITIDLRLSHQAIAEAIGSTRVTITRLLGDLKDSGLLNIERKKITVFDPIALS
KRFN
>Mature_244_residues
MIPSSRGFSRFNSQQSGQSKINSVGERFPINRTLMEVIRGLEGASTEMVERSKTIFFPGDPAERVYLIRRGAVRLSRVYE
SGEEITVALLRENSLFGVLSLLTGHRSDRFYHSIAFTRVEMITAPANSVLRAIEEDASVGLLLLQGLSSRILQTETMIET
LTHRDMSSRLVSFLMVLCRDFGVASEKGITIDLRLSHQAIAEAIGSTRVTITRLLGDLKDSGLLNIERKKITVFDPIALS
KRFN

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27221; Mature: 27221

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSSRGFSRFNSQQSGQSKINSVGERFPINRTLMEVIRGLEGASTEMVERSKTIFFPGD
CCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHCCCEEEECCC
PAERVYLIRRGAVRLSRVYESGEEITVALLRENSLFGVLSLLTGHRSDRFYHSIAFTRVE
CHHHEEEHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHH
MITAPANSVLRAIEEDASVGLLLLQGLSSRILQTETMIETLTHRDMSSRLVSFLMVLCRD
HHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FGVASEKGITIDLRLSHQAIAEAIGSTRVTITRLLGDLKDSGLLNIERKKITVFDPIALS
CCCCCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCEEEEECCHHHC
KRFN
CCCC
>Mature Secondary Structure
MIPSSRGFSRFNSQQSGQSKINSVGERFPINRTLMEVIRGLEGASTEMVERSKTIFFPGD
CCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHCCCEEEECCC
PAERVYLIRRGAVRLSRVYESGEEITVALLRENSLFGVLSLLTGHRSDRFYHSIAFTRVE
CHHHEEEHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHH
MITAPANSVLRAIEEDASVGLLLLQGLSSRILQTETMIETLTHRDMSSRLVSFLMVLCRD
HHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FGVASEKGITIDLRLSHQAIAEAIGSTRVTITRLLGDLKDSGLLNIERKKITVFDPIALS
CCCCCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCEEEEECCHHHC
KRFN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8366058; 8905231 [H]