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The map label for this gene is trxB [H]

Identifier: 78778599

GI number: 78778599

Start: 205551

End: 206507

Strand: Direct

Name: trxB [H]

Synonym: PMT9312_0213

Alternate gene names: 78778599

Gene position: 205551-206507 (Clockwise)

Preceding gene: 78778596

Following gene: 78778603

Centisome position: 12.03

GC content: 37.3

Gene sequence:

>957_bases
TTGGAAATCATCGAGTCAGATGTAGTTATTATCGGAGGAGGTCCGGCAGGATGTACTTGCGCACTTTATACATCTCGTTC
AAACTTAAAGACGGTAATTTTAGATAAAAATCCATCTGTTGGCGCCTTAGCAATAACTCATCAGATAGCTAATTATCCAG
GCGTGCCAGTTGATATAAGTGGAGAGAAATTACTTACTTTAATGAGAGAACAGGCTGTGCAATACGGTACAGACTACAGA
AGAGCACAAGTGTTTGGAATAGACGCTAGTGGAGAATGGAAAACGGTTTTTACGCCTGAGGGCACCTTCAAGGCCAAAGC
ACTTGTTCTTGCAAGTGGAGCTATGGGTAGGCCTGCATCATTTAAGGGTGAAGCTGATTTTCTTGGCAAAGGAGTAAGTT
ATTGTGCTACATGTGATGGAGCTTTTTATAAAAATAGAGAAGTTGCCGTTGTTGGAGTGAACAAGGAGGCAATTGAAGAG
GCAACTGTTCTTACTAAATTTGCTTCTACTGTACATTGGATTACATCAAGTGATCCTAAATCAGATAATGAAGAAGCTAT
GGAATTGATTGATAATTCAAATATAAAGCATTGGAGTAGAACGAGATTATTGGAAATATTGGGTGATGATATGGGGGTAA
ATGGGGTTATTGTAAAAAATAAGCAAGAAGAAAATCCTATTAATTTAAATTTAGATGGAGTCTTTGTCTACATGAGTGGT
TCAAAGCCAATTACTGATTTTTTAGGGGATCAAATTGCTTTAAAAGATGACGGAGGAGTTATTGTGGATGACTTTATGTC
TACAAACTCTGATGGAGTATGGGCTATTGGAGATATAAGAAATACACCATTTAAGCAAGCCGTTGTTGCAGCTTCAGATG
GATGTATTGCCGCAATGTCAATTGATAGATATTTGAATAGTAGAAAAAATATAAGAGTTGATTGGATTCATTCTTAA

Upstream 100 bases:

>100_bases
TTCTTTTAACTTATATCTATATAAAGGTTAGGTTTTAACATTAAAGATATCTTCTAACCAAAAACTCATCTAATTAACTA
ATAAAAGGAGTTTTATTAAA

Downstream 100 bases:

>100_bases
AAAATAAATATTACTTCTTTAATTTAGAGGGGTGTTGCTTCAGAAATATAAGCGACTCCGCCGTAATAGCTTAAATCTTC
CCTAATGTTATCTCTCATTT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDISGEKLLTLMREQAVQYGTDYR
RAQVFGIDASGEWKTVFTPEGTFKAKALVLASGAMGRPASFKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEE
ATVLTKFASTVHWITSSDPKSDNEEAMELIDNSNIKHWSRTRLLEILGDDMGVNGVIVKNKQEENPINLNLDGVFVYMSG
SKPITDFLGDQIALKDDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMSIDRYLNSRKNIRVDWIHS

Sequences:

>Translated_318_residues
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDISGEKLLTLMREQAVQYGTDYR
RAQVFGIDASGEWKTVFTPEGTFKAKALVLASGAMGRPASFKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEE
ATVLTKFASTVHWITSSDPKSDNEEAMELIDNSNIKHWSRTRLLEILGDDMGVNGVIVKNKQEENPINLNLDGVFVYMSG
SKPITDFLGDQIALKDDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMSIDRYLNSRKNIRVDWIHS
>Mature_318_residues
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDISGEKLLTLMREQAVQYGTDYR
RAQVFGIDASGEWKTVFTPEGTFKAKALVLASGAMGRPASFKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEE
ATVLTKFASTVHWITSSDPKSDNEEAMELIDNSNIKHWSRTRLLEILGDDMGVNGVIVKNKQEENPINLNLDGVFVYMSG
SKPITDFLGDQIALKDDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMSIDRYLNSRKNIRVDWIHS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=35.7827476038339, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=29.5081967213115, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=32.1875, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=327, Percent_Identity=30.5810397553517, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34397; Mature: 34397

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00066 HMG_COA_REDUCTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDIS
CCEECCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEHHHCCCCCEEEEC
GEKLLTLMREQAVQYGTDYRRAQVFGIDASGEWKTVFTPEGTFKAKALVLASGAMGRPAS
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
FKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEEATVLTKFASTVHWITSSDPK
CCCCHHHHCCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
SDNEEAMELIDNSNIKHWSRTRLLEILGDDMGVNGVIVKNKQEENPINLNLDGVFVYMSG
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECEEEEEEEC
SKPITDFLGDQIALKDDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMS
CCCHHHHCCCEEEEECCCCEEEEHHHCCCCCCEEEEECCCCCCHHHEEEEECCCEEEEEE
IDRYLNSRKNIRVDWIHS
HHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDIS
CCEECCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEHHHCCCCCEEEEC
GEKLLTLMREQAVQYGTDYRRAQVFGIDASGEWKTVFTPEGTFKAKALVLASGAMGRPAS
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
FKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEEATVLTKFASTVHWITSSDPK
CCCCHHHHCCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
SDNEEAMELIDNSNIKHWSRTRLLEILGDDMGVNGVIVKNKQEENPINLNLDGVFVYMSG
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECEEEEEEEC
SKPITDFLGDQIALKDDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMS
CCCHHHHCCCEEEEECCCCEEEEHHHCCCCCCEEEEECCCCCCHHHEEEEECCCEEEEEE
IDRYLNSRKNIRVDWIHS
HHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]