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The map label for this gene is thiL [H]

Identifier: 78778409

GI number: 78778409

Start: 25210

End: 26196

Strand: Reverse

Name: thiL [H]

Synonym: PMT9312_0024

Alternate gene names: 78778409

Gene position: 26196-25210 (Counterclockwise)

Preceding gene: 78778410

Following gene: 78778407

Centisome position: 1.53

GC content: 30.19

Gene sequence:

>987_bases
ATGCATAAAGAAATATTAGAAAATATAGGGGAAAAAGAATTAATAACTAGGCTTGGAAAATTTATGCCTAAAAATCAAGT
TACAGATGATTGTGCTTTAATAAAAACTAAAAATAATAACTTACTTGTTAATAATGATTCTTTGGTAGAAGATGTTCATT
TCAATGACATTACTATTTGCCCTCAAGACCTCGGATGGAAAGCAGTTGTCAGCAACATCTCTGACTTATTATCCAGTGGT
AGCAAGAAAACTATAGGAATTACAATAAGTTTGATTCTACCTGCTAAAACTGAGTGGGTTTGGGTTGAAGAGTTATATAA
AGGAATAAATAAAGCTTTAAAAGAATATGGCGGAAAAATTCTTGGAGGAGATTGCTCAAAGGGAAATCAAAAAACCATAT
CAATTACAGCCTTTGGAATTCAAGGTGAACTCGAATTACGAAGAAACGCATGTAAACCAGGGGATATTATCTTAACCACA
GGAATTCATGGACTTAGCAAACTAGGATTTTTGATACAAAATAAAATAAAGTTAGATAATAATATTTCTCTTAATGAAAG
ATTAATCAGTAAGTCCATTGAACGTTTTTGTCGCCCTCAAGTTTACCCAAATTTTCTAAAAAATCTCCTTAAAACTCGCA
CAAATAAAAAAATAAAGAGAATAGGTTGTACTGATAGCAGTGATGGTCTATTTCAAGCGGTACAAGATTTAGCAATCGCT
AGCAAATGTAAAGCAATTATGATTTATAAAAAAATACCTAAAGATAAGGATTGGCCAAAGGGAGATAAATGGGATGAATA
TTATTTTTTTGGAGGTGAAGATTACGAATTAGTTTTCTCATTGCCCAAAAAATGGGCAAAGAATTTATCTAAACTTGATA
AAACTATTAATGCAATTGGTTATTTTGCTCATGGTGAACCATCAATAGAATTTAAAGATAATAATAAAAATAAATTATTG
AAAAACTCACCTTTCAAGCACTTTTAA

Upstream 100 bases:

>100_bases
GGTTATGTTGTAGATGGTTTTGATGTATTGGAAGAACTAACGAAAGATGACACAATAATCTCAATAGATGTTTTAGCAGG
GATTGAAAACCTCAAATTAA

Downstream 100 bases:

>100_bases
TTATTCCCACTTTTTAGCAACAATCTCTGCCAAATCAACGACCCTCTGGCTATAACCCCACTCGTTGTCATACCATGCAA
GGACCTTGACAAGATTATCT

Product: thiamine-phosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MHKEILENIGEKELITRLGKFMPKNQVTDDCALIKTKNNNLLVNNDSLVEDVHFNDITICPQDLGWKAVVSNISDLLSSG
SKKTIGITISLILPAKTEWVWVEELYKGINKALKEYGGKILGGDCSKGNQKTISITAFGIQGELELRRNACKPGDIILTT
GIHGLSKLGFLIQNKIKLDNNISLNERLISKSIERFCRPQVYPNFLKNLLKTRTNKKIKRIGCTDSSDGLFQAVQDLAIA
SKCKAIMIYKKIPKDKDWPKGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKTINAIGYFAHGEPSIEFKDNNKNKLL
KNSPFKHF

Sequences:

>Translated_328_residues
MHKEILENIGEKELITRLGKFMPKNQVTDDCALIKTKNNNLLVNNDSLVEDVHFNDITICPQDLGWKAVVSNISDLLSSG
SKKTIGITISLILPAKTEWVWVEELYKGINKALKEYGGKILGGDCSKGNQKTISITAFGIQGELELRRNACKPGDIILTT
GIHGLSKLGFLIQNKIKLDNNISLNERLISKSIERFCRPQVYPNFLKNLLKTRTNKKIKRIGCTDSSDGLFQAVQDLAIA
SKCKAIMIYKKIPKDKDWPKGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKTINAIGYFAHGEPSIEFKDNNKNKLL
KNSPFKHF
>Mature_328_residues
MHKEILENIGEKELITRLGKFMPKNQVTDDCALIKTKNNNLLVNNDSLVEDVHFNDITICPQDLGWKAVVSNISDLLSSG
SKKTIGITISLILPAKTEWVWVEELYKGINKALKEYGGKILGGDCSKGNQKTISITAFGIQGELELRRNACKPGDIILTT
GIHGLSKLGFLIQNKIKLDNNISLNERLISKSIERFCRPQVYPNFLKNLLKTRTNKKIKRIGCTDSSDGLFQAVQDLAIA
SKCKAIMIYKKIPKDKDWPKGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKTINAIGYFAHGEPSIEFKDNNKNKLL
KNSPFKHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=281, Percent_Identity=30.2491103202847, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 37100; Mature: 37100

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKEILENIGEKELITRLGKFMPKNQVTDDCALIKTKNNNLLVNNDSLVEDVHFNDITIC
CCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEECCCCHHEECCCCCEEEC
PQDLGWKAVVSNISDLLSSGSKKTIGITISLILPAKTEWVWVEELYKGINKALKEYGGKI
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCEE
LGGDCSKGNQKTISITAFGIQGELELRRNACKPGDIILTTGIHGLSKLGFLIQNKIKLDN
ECCCCCCCCCEEEEEEEEECCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEECCC
NISLNERLISKSIERFCRPQVYPNFLKNLLKTRTNKKIKRIGCTDSSDGLFQAVQDLAIA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHEECCCCCCCHHHHHHHHHHHH
SKCKAIMIYKKIPKDKDWPKGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKTINAIG
HHCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHE
YFAHGEPSIEFKDNNKNKLLKNSPFKHF
EEECCCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHKEILENIGEKELITRLGKFMPKNQVTDDCALIKTKNNNLLVNNDSLVEDVHFNDITIC
CCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEECCCCHHEECCCCCEEEC
PQDLGWKAVVSNISDLLSSGSKKTIGITISLILPAKTEWVWVEELYKGINKALKEYGGKI
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCEE
LGGDCSKGNQKTISITAFGIQGELELRRNACKPGDIILTTGIHGLSKLGFLIQNKIKLDN
ECCCCCCCCCEEEEEEEEECCCHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEECCC
NISLNERLISKSIERFCRPQVYPNFLKNLLKTRTNKKIKRIGCTDSSDGLFQAVQDLAIA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHEECCCCCCCHHHHHHHHHHHH
SKCKAIMIYKKIPKDKDWPKGDKWDEYYFFGGEDYELVFSLPKKWAKNLSKLDKTINAIG
HHCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHE
YFAHGEPSIEFKDNNKNKLLKNSPFKHF
EEECCCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA