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The map label for this gene is gap2 [H]

Identifier: 78778408

GI number: 78778408

Start: 24187

End: 25209

Strand: Direct

Name: gap2 [H]

Synonym: PMT9312_0023

Alternate gene names: 78778408

Gene position: 24187-25209 (Clockwise)

Preceding gene: 78778404

Following gene: 78778411

Centisome position: 1.42

GC content: 37.24

Gene sequence:

>1023_bases
ATGACTTTGCGTGTTGCAATTAACGGCTTTGGCAGAATTGGTAGAAACTTTATGCGCTGTTGGCTTAGTAGAGGTGCTTA
TACCAACATTGAAGTTGTTGGTATTAATGTTACTTCAGATCCAAAGACGAATGCTCATCTTCTAAAATACGATTCAGTTC
TTGGCCAATTGGATGGTGTTGATATTCAATATACTGATGACACTTTTGTAATTAATAATAAGACTATTAAGTGTTTTTCT
GATAGAAACCCAATGAATCTCCCTTGGAAAGACTGGGGAGTTGACTTAGTAATTGAATCAACGGGAGTTTTTAATACAGA
TGTAGGGGCAAGTAAGCACTTAGAAGTAGGGGCAAAAAAAGTTATCTTAACTGCTCCGGGTAAAGGGGATGGGGTTGGTA
CTTATGTAGTTGGAGTTAATGCTGATCAATATAATCATAAAGATTATGATATTTTAAGTAATGCTAGTTGTACTACAAAT
TGTTTAGCTCCAGTAGTTAAAGTTTTAGATCAAAATTTTGGTATTAATAAAGGTTTGATGACTACAATTCATAGTTATAC
CGGTGATCAAAGAATTCTAGATAATAGTCATAGAGATTTAAGAAGGGCTAGAGCCGCTGCCACCAATATTGTTCCAACTT
CTACAGGAGCTGCTAAAGCAGTAGCATTAGTGTATCCAGAAATGAAAGGCAAATTGACAGGAATTGCAATGAGGGTTCCT
ACACCTAACGTTTCAGCGGTAGATTTCGTTTTCGAATCCTCTAAATCTGTCACAAGCGAAGAAGTAAATAATGCTCTTAA
AGAAGCATCTTTAGGTTCAATGCAGGGCATCATTAAGTACGGAGATGAACCATTAGTGTCAAGCGATTATGCAGGTACTA
ATGAATCATCAATTGTAGATAGTGACCTCACTATGTGCATCGGAGATAATCTTGTCAAGGTCCTTGCATGGTATGACAAC
GAGTGGGGTTATAGCCAGAGGGTCGTTGATTTGGCAGAGATTGTTGCTAAAAAGTGGGAATAA

Upstream 100 bases:

>100_bases
AACTAGACTTATTTGCTTAATAAATCAAAAAAACCTTACGTTATTGCACAAAATTCAGTATGATCAGCAACTTAGGTTAA
TCATTTAGAAATTTTTAGTT

Downstream 100 bases:

>100_bases
TTAAAAGTGCTTGAAAGGTGAGTTTTTCAATAATTTATTTTTATTATTATCTTTAAATTCTATTGATGGTTCACCATGAG
CAAAATAACCAATTGCATTA

Product: glyceraldehyde 3-phosphate dehydrogenase(NADP+)(phosphorylating)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGVDIQYTDDTFVINNKTIKCFS
DRNPMNLPWKDWGVDLVIESTGVFNTDVGASKHLEVGAKKVILTAPGKGDGVGTYVVGVNADQYNHKDYDILSNASCTTN
CLAPVVKVLDQNFGINKGLMTTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
TPNVSAVDFVFESSKSVTSEEVNNALKEASLGSMQGIIKYGDEPLVSSDYAGTNESSIVDSDLTMCIGDNLVKVLAWYDN
EWGYSQRVVDLAEIVAKKWE

Sequences:

>Translated_340_residues
MTLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGVDIQYTDDTFVINNKTIKCFS
DRNPMNLPWKDWGVDLVIESTGVFNTDVGASKHLEVGAKKVILTAPGKGDGVGTYVVGVNADQYNHKDYDILSNASCTTN
CLAPVVKVLDQNFGINKGLMTTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
TPNVSAVDFVFESSKSVTSEEVNNALKEASLGSMQGIIKYGDEPLVSSDYAGTNESSIVDSDLTMCIGDNLVKVLAWYDN
EWGYSQRVVDLAEIVAKKWE
>Mature_339_residues
TLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGVDIQYTDDTFVINNKTIKCFSD
RNPMNLPWKDWGVDLVIESTGVFNTDVGASKHLEVGAKKVILTAPGKGDGVGTYVVGVNADQYNHKDYDILSNASCTTNC
LAPVVKVLDQNFGINKGLMTTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVPT
PNVSAVDFVFESSKSVTSEEVNNALKEASLGSMQGIIKYGDEPLVSSDYAGTNESSIVDSDLTMCIGDNLVKVLAWYDNE
WGYSQRVVDLAEIVAKKWE

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=44.4108761329305, Blast_Score=291, Evalue=6e-79,
Organism=Homo sapiens, GI7669492, Length=341, Percent_Identity=43.4017595307918, Blast_Score=273, Evalue=2e-73,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=47.9289940828402, Blast_Score=317, Evalue=6e-88,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=43.030303030303, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17534679, Length=344, Percent_Identity=43.8953488372093, Blast_Score=279, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17534677, Length=344, Percent_Identity=43.8953488372093, Blast_Score=278, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17568413, Length=344, Percent_Identity=43.3139534883721, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI32566163, Length=344, Percent_Identity=43.3139534883721, Blast_Score=275, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=48.0825958702065, Blast_Score=310, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6322468, Length=340, Percent_Identity=47.3529411764706, Blast_Score=308, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6322409, Length=340, Percent_Identity=46.7647058823529, Blast_Score=303, Evalue=2e-83,
Organism=Drosophila melanogaster, GI85725000, Length=340, Percent_Identity=45, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI22023983, Length=340, Percent_Identity=45, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI17933600, Length=340, Percent_Identity=44.4117647058823, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI18110149, Length=340, Percent_Identity=44.4117647058823, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=44.3768996960486, Blast_Score=270, Evalue=1e-72,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37073; Mature: 36942

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHCCCC
DIQYTDDTFVINNKTIKCFSDRNPMNLPWKDWGVDLVIESTGVFNTDVGASKHLEVGAKK
EEEECCCEEEEECCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCCEEECCCEE
VILTAPGKGDGVGTYVVGVNADQYNHKDYDILSNASCTTNCLAPVVKVLDQNFGINKGLM
EEEECCCCCCCCEEEEEEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHH
TTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
HHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECC
TPNVSAVDFVFESSKSVTSEEVNNALKEASLGSMQGIIKYGDEPLVSSDYAGTNESSIVD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEC
SDLTMCIGDNLVKVLAWYDNEWGYSQRVVDLAEIVAKKWE
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLRVAINGFGRIGRNFMRCWLSRGAYTNIEVVGINVTSDPKTNAHLLKYDSVLGQLDGV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHCCCC
DIQYTDDTFVINNKTIKCFSDRNPMNLPWKDWGVDLVIESTGVFNTDVGASKHLEVGAKK
EEEECCCEEEEECCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCCEEECCCEE
VILTAPGKGDGVGTYVVGVNADQYNHKDYDILSNASCTTNCLAPVVKVLDQNFGINKGLM
EEEECCCCCCCCEEEEEEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHH
TTIHSYTGDQRILDNSHRDLRRARAAATNIVPTSTGAAKAVALVYPEMKGKLTGIAMRVP
HHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECC
TPNVSAVDFVFESSKSVTSEEVNNALKEASLGSMQGIIKYGDEPLVSSDYAGTNESSIVD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEC
SDLTMCIGDNLVKVLAWYDNEWGYSQRVVDLAEIVAKKWE
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]