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The map label for this gene is rsbU [H]

Identifier: 78778396

GI number: 78778396

Start: 13177

End: 14520

Strand: Direct

Name: rsbU [H]

Synonym: PMT9312_0011

Alternate gene names: 78778396

Gene position: 13177-14520 (Clockwise)

Preceding gene: 78778395

Following gene: 78778397

Centisome position: 0.77

GC content: 27.23

Gene sequence:

>1344_bases
TTGACAAATAATCAAAAAGAAAAATTATTTTCAAACAAATTTATTCAAAAATTTTTAGAAAACGAATCAAAAGTATCTTT
AAACAATAAATATAAATTTGCTGAAATTGCATCTTCATTATCATATTATTTAAAAACCTTTTCCAATATAAATAAATTAC
TTGATTTTATATGCTTAATTTTTAAACATATTTTTAAAGAAAAAATAATATTAATTATTCCTTTAAATTATGAGGGAGAA
ATATGGAATGAAAACATAAAAATTTCCGCTAATAATGAATTTTTTAGAATTCAAGAAGAAATTAATAGTTTTTTTAACAA
ATTTAATTTTTCTAAAAATTTTAAAATAAAAGAAATTCTAACTTTTGAAAATGCTCTGAAAAATAATTTTAAAGAATATA
AAATAGAAACAGAAAAAATACTATCTAGGGGAAAATGCAGAGGATTTACATATATTTTAAGCAAAGATTCATCAGGGGAT
TCCATAACTCATGATTCTAATTTTATTTTTATCCAAAATTGTCTTGCTGTTGGATTAGAGAATTACTGCTTAATTAAAAT
AAAGAAAAAGCATGAAAATGTAGATAGAGAAATTTCTACTGGGGCTGAGATTCAATCTCAATTACTTCCAGATTATTGTC
CCATTATTTATGGTATAGATCTTGCTGCACATTGTAGACCTGCTCTCCAATTAGGTGGAGATTATTATGATTTTATGTGC
TTAAAAACGAATATTTCAGACAAAAGGAAAGAAAAAGCTAGGTGGGCGTTAGTAATTGGTGATGTTATGGGTAAGGGTAT
TCCAGCTGGTCTTCTAATGACTATGCTAAGAGGAATGTTACGTGCAGAGGTTCTTACAGGGTTACCTCCAGATAGAATTT
TGCATGACTTGAATCAACTAGCAATAAATGATTTAGATCAATCCCATAGATTTGTCACGTTATTTTATTCTGATTATGAT
CCTAGAACTAGAAAATTGAGATTTGCCAATGCAGCACATAACCCCCCTTTGCTCTGGAAAAGTTTAGATCAAAAAATTAT
AAGATTAGATGCAGAAGGATTTGTACTTGGACTTCAAAAAGACGCTGAATATCATTGTGGTGAAATTAAGCTTAATAAAA
ATGATTTAGTGCTTTATTACACTGATGGAGTTATCGATACCTCTAATTCCTTAGGCGAAAGGTTTGATGAGGAAAGGTTA
ATTAAAACCCTTACAAAATTATGCAAGCAATCCTATACATCTCAAGAAATTTTAAATAAAATTTTTAAAAAATTAGATGA
CTTTACAGGACAAAATAGACATCTCGAAGATGATGCATCAATGGTTATTTTTCAAATTAATTAG

Upstream 100 bases:

>100_bases
CGAATTTGTAGAGGCTATGCTTGCAGATAAATAAATTTTTAAAAATTTTATTTAAAACTTTAAATTTAATGTTAAAACAT
ATTTAACTATTAGATTTGTT

Downstream 100 bases:

>100_bases
ATATTTTTTGTCACTAATATAAAAAAATGCTTTATTAGAGATATCTAAAGTTACTAATTGATATGGCAAAAGTTTGGAGT
AAAAGATTCGATAATACACT

Product: serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTNNQKEKLFSNKFIQKFLENESKVSLNNKYKFAEIASSLSYYLKTFSNINKLLDFICLIFKHIFKEKIILIIPLNYEGE
IWNENIKISANNEFFRIQEEINSFFNKFNFSKNFKIKEILTFENALKNNFKEYKIETEKILSRGKCRGFTYILSKDSSGD
SITHDSNFIFIQNCLAVGLENYCLIKIKKKHENVDREISTGAEIQSQLLPDYCPIIYGIDLAAHCRPALQLGGDYYDFMC
LKTNISDKRKEKARWALVIGDVMGKGIPAGLLMTMLRGMLRAEVLTGLPPDRILHDLNQLAINDLDQSHRFVTLFYSDYD
PRTRKLRFANAAHNPPLLWKSLDQKIIRLDAEGFVLGLQKDAEYHCGEIKLNKNDLVLYYTDGVIDTSNSLGERFDEERL
IKTLTKLCKQSYTSQEILNKIFKKLDDFTGQNRHLEDDASMVIFQIN

Sequences:

>Translated_447_residues
MTNNQKEKLFSNKFIQKFLENESKVSLNNKYKFAEIASSLSYYLKTFSNINKLLDFICLIFKHIFKEKIILIIPLNYEGE
IWNENIKISANNEFFRIQEEINSFFNKFNFSKNFKIKEILTFENALKNNFKEYKIETEKILSRGKCRGFTYILSKDSSGD
SITHDSNFIFIQNCLAVGLENYCLIKIKKKHENVDREISTGAEIQSQLLPDYCPIIYGIDLAAHCRPALQLGGDYYDFMC
LKTNISDKRKEKARWALVIGDVMGKGIPAGLLMTMLRGMLRAEVLTGLPPDRILHDLNQLAINDLDQSHRFVTLFYSDYD
PRTRKLRFANAAHNPPLLWKSLDQKIIRLDAEGFVLGLQKDAEYHCGEIKLNKNDLVLYYTDGVIDTSNSLGERFDEERL
IKTLTKLCKQSYTSQEILNKIFKKLDDFTGQNRHLEDDASMVIFQIN
>Mature_446_residues
TNNQKEKLFSNKFIQKFLENESKVSLNNKYKFAEIASSLSYYLKTFSNINKLLDFICLIFKHIFKEKIILIIPLNYEGEI
WNENIKISANNEFFRIQEEINSFFNKFNFSKNFKIKEILTFENALKNNFKEYKIETEKILSRGKCRGFTYILSKDSSGDS
ITHDSNFIFIQNCLAVGLENYCLIKIKKKHENVDREISTGAEIQSQLLPDYCPIIYGIDLAAHCRPALQLGGDYYDFMCL
KTNISDKRKEKARWALVIGDVMGKGIPAGLLMTMLRGMLRAEVLTGLPPDRILHDLNQLAINDLDQSHRFVTLFYSDYDP
RTRKLRFANAAHNPPLLWKSLDQKIIRLDAEGFVLGLQKDAEYHCGEIKLNKNDLVLYYTDGVIDTSNSLGERFDEERLI
KTLTKLCKQSYTSQEILNKIFKKLDDFTGQNRHLEDDASMVIFQIN

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 51878; Mature: 51747

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNQKEKLFSNKFIQKFLENESKVSLNNKYKFAEIASSLSYYLKTFSNINKLLDFICLI
CCCCHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKHIFKEKIILIIPLNYEGEIWNENIKISANNEFFRIQEEINSFFNKFNFSKNFKIKEIL
HHHHHHCCEEEEEEECCCCCEECCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCHHHHH
TFENALKNNFKEYKIETEKILSRGKCRGFTYILSKDSSGDSITHDSNFIFIQNCLAVGLE
HHHHHHHCCHHHHEECHHHHHHCCCCCCEEEEEECCCCCCCEECCCCEEEEEHHHHHCCC
NYCLIKIKKKHENVDREISTGAEIQSQLLPDYCPIIYGIDLAAHCRPALQLGGDYYDFMC
CEEEEEEECCCCCCCHHHHCCHHHHHHHCCCHHHHHCCCCHHHHCCHHHHCCCCEEEEEE
LKTNISDKRKEKARWALVIGDVMGKGIPAGLLMTMLRGMLRAEVLTGLPPDRILHDLNQL
EECCCCHHHHHHHHEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AINDLDQSHRFVTLFYSDYDPRTRKLRFANAAHNPPLLWKSLDQKIIRLDAEGFVLGLQK
HHHCCCCCCCEEEEEEECCCCCHHEEEEECCCCCCCHHHHHHHHHHEEECCCCEEEEEEC
DAEYHCGEIKLNKNDLVLYYTDGVIDTSNSLGERFDEERLIKTLTKLCKQSYTSQEILNK
CCCCCCCEEEECCCCEEEEEECCEEECCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH
IFKKLDDFTGQNRHLEDDASMVIFQIN
HHHHHHHCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
TNNQKEKLFSNKFIQKFLENESKVSLNNKYKFAEIASSLSYYLKTFSNINKLLDFICLI
CCCHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKHIFKEKIILIIPLNYEGEIWNENIKISANNEFFRIQEEINSFFNKFNFSKNFKIKEIL
HHHHHHCCEEEEEEECCCCCEECCEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCHHHHH
TFENALKNNFKEYKIETEKILSRGKCRGFTYILSKDSSGDSITHDSNFIFIQNCLAVGLE
HHHHHHHCCHHHHEECHHHHHHCCCCCCEEEEEECCCCCCCEECCCCEEEEEHHHHHCCC
NYCLIKIKKKHENVDREISTGAEIQSQLLPDYCPIIYGIDLAAHCRPALQLGGDYYDFMC
CEEEEEEECCCCCCCHHHHCCHHHHHHHCCCHHHHHCCCCHHHHCCHHHHCCCCEEEEEE
LKTNISDKRKEKARWALVIGDVMGKGIPAGLLMTMLRGMLRAEVLTGLPPDRILHDLNQL
EECCCCHHHHHHHHEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AINDLDQSHRFVTLFYSDYDPRTRKLRFANAAHNPPLLWKSLDQKIIRLDAEGFVLGLQK
HHHCCCCCCCEEEEEEECCCCCHHEEEEECCCCCCCHHHHHHHHHHEEECCCCEEEEEEC
DAEYHCGEIKLNKNDLVLYYTDGVIDTSNSLGERFDEERLIKTLTKLCKQSYTSQEILNK
CCCCCCCEEEECCCCEEEEEECCEEECCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH
IFKKLDDFTGQNRHLEDDASMVIFQIN
HHHHHHHCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]