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The map label for this gene is 78358296

Identifier: 78358296

GI number: 78358296

Start: 3254855

End: 3255910

Strand: Reverse

Name: 78358296

Synonym: Dde_3256

Alternate gene names: NA

Gene position: 3255910-3254855 (Counterclockwise)

Preceding gene: 78358297

Following gene: 78358295

Centisome position: 87.28

GC content: 49.62

Gene sequence:

>1056_bases
ATGATTAGTGTGGAGGTAGCCGTGAACGAGGTAGTCATCGCCGGAAGAAAATTAGGTCCGCAGCATCCACCGCTTGTTAT
TGCGGAAATCGGAATCAACCATGAAGGTGACTGCGATAAGGCACTTCGTATGGTTGAGGCTGCCGCACAGGCAGGCTGCG
AGTGCGTCAAAATTCAGACTCACATCATTGAAGATGAGATGGTACCTAATGATGTTGTTCCGGGGAATGCGAAGGAAAGC
ATCTGGAACATCATGTCCCGTTGCGCACTAACCAGAGAAGAAGAGGTGTGTATCAAGCGTCGGACTGAAGAGCTTGGTAT
GATTTTTCTTTCAACTCCGTTTTCACGTGCTGCCGCGGATCAGCTTGAATCCATGGGGGTGACTGCCTATAAAATAGGCT
CCGGAGAATGTAATAATTACCCTCTGATCCGCCATGTGGCTTCATTCGGAAAGCCGGTCATCCTCAGCACAGGTATGAAT
GACATCAGCTCCATTGAACCGGCTGTCGCTATTTTCCGGGAGCTGAAAACAGACTATGTGTTGATGCACTGCACGTCATT
GTATCCCACTCCATACGAAAAGGTCCGGCTGGGAGCGCTGGGAGATCTTAAAAAAGCATTTCCTGATGCGGTGTTGGGGC
TTTCAGATCATTCGCTCGGCAACTATACATGCTATGCAGCCGTTGCCTTAGGGGCGTCGGTTTTAGAAAAACATTTTACC
TGTGATAAACTGTGGCCGGGACCCGATGTTCCCATTTCTGTCGACCCCGGCGAACTGAAGCGGCTGGTCGAAGGAACTCG
GGCTGTCCATCAGGCAATGGGCGGCCACAAAGAAATTTTGCCCGACGAAAAGCCTACAATCGATTTTGCATATGCAAGCG
TTGTTGCCATAAGAGATATCCGTGCCGGGGATATCCTCAGTAAAGATAATATCTGGGTCAAGCGCCCGGGAACCGGTGAG
ATTTTAGCCAGAGACTACGAGCGTGTTTTGGGAAGAGTGGCAAAACGACCATTACAAAAAAATGCCCAGCTGGCATGGGA
TGATTTTGATGGCTAA

Upstream 100 bases:

>100_bases
GGCTCCACGGGTATGTGGTGCCGCTGGAACGATCTCTGCAAGTGGATAGCGATTATGAGTTGAATATTGCGGATCTGCTG
TTAAGCCAGCGCAGCCGCGG

Downstream 100 bases:

>100_bases
AAAAAAGATACTCTTTATTACGGGCACCCGCGCTGACTTTGGCAAGTTATGTAGCCTCATTGATAAAGTGAGCGAGCATA
CCGAGTTTGAGTATTGTATT

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MISVEVAVNEVVIAGRKLGPQHPPLVIAEIGINHEGDCDKALRMVEAAAQAGCECVKIQTHIIEDEMVPNDVVPGNAKES
IWNIMSRCALTREEEVCIKRRTEELGMIFLSTPFSRAAADQLESMGVTAYKIGSGECNNYPLIRHVASFGKPVILSTGMN
DISSIEPAVAIFRELKTDYVLMHCTSLYPTPYEKVRLGALGDLKKAFPDAVLGLSDHSLGNYTCYAAVALGASVLEKHFT
CDKLWPGPDVPISVDPGELKRLVEGTRAVHQAMGGHKEILPDEKPTIDFAYASVVAIRDIRAGDILSKDNIWVKRPGTGE
ILARDYERVLGRVAKRPLQKNAQLAWDDFDG

Sequences:

>Translated_351_residues
MISVEVAVNEVVIAGRKLGPQHPPLVIAEIGINHEGDCDKALRMVEAAAQAGCECVKIQTHIIEDEMVPNDVVPGNAKES
IWNIMSRCALTREEEVCIKRRTEELGMIFLSTPFSRAAADQLESMGVTAYKIGSGECNNYPLIRHVASFGKPVILSTGMN
DISSIEPAVAIFRELKTDYVLMHCTSLYPTPYEKVRLGALGDLKKAFPDAVLGLSDHSLGNYTCYAAVALGASVLEKHFT
CDKLWPGPDVPISVDPGELKRLVEGTRAVHQAMGGHKEILPDEKPTIDFAYASVVAIRDIRAGDILSKDNIWVKRPGTGE
ILARDYERVLGRVAKRPLQKNAQLAWDDFDG
>Mature_351_residues
MISVEVAVNEVVIAGRKLGPQHPPLVIAEIGINHEGDCDKALRMVEAAAQAGCECVKIQTHIIEDEMVPNDVVPGNAKES
IWNIMSRCALTREEEVCIKRRTEELGMIFLSTPFSRAAADQLESMGVTAYKIGSGECNNYPLIRHVASFGKPVILSTGMN
DISSIEPAVAIFRELKTDYVLMHCTSLYPTPYEKVRLGALGDLKKAFPDAVLGLSDHSLGNYTCYAAVALGASVLEKHFT
CDKLWPGPDVPISVDPGELKRLVEGTRAVHQAMGGHKEILPDEKPTIDFAYASVVAIRDIRAGDILSKDNIWVKRPGTGE
ILARDYERVLGRVAKRPLQKNAQLAWDDFDG

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=330, Percent_Identity=34.5454545454545, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21357081, Length=337, Percent_Identity=29.673590504451, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38405; Mature: 38405

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVEVAVNEVVIAGRKLGPQHPPLVIAEIGINHEGDCDKALRMVEAAAQAGCECVKIQT
CEEEEEEHHHHEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEHH
HIIEDEMVPNDVVPGNAKESIWNIMSRCALTREEEVCIKRRTEELGMIFLSTPFSRAAAD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCHHHHHH
QLESMGVTAYKIGSGECNNYPLIRHVASFGKPVILSTGMNDISSIEPAVAIFRELKTDYV
HHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCEE
LMHCTSLYPTPYEKVRLGALGDLKKAFPDAVLGLSDHSLGNYTCYAAVALGASVLEKHFT
EEEEHHCCCCCHHHEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
CDKLWPGPDVPISVDPGELKRLVEGTRAVHQAMGGHKEILPDEKPTIDFAYASVVAIRDI
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHCC
RAGDILSKDNIWVKRPGTGEILARDYERVLGRVAKRPLQKNAQLAWDDFDG
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MISVEVAVNEVVIAGRKLGPQHPPLVIAEIGINHEGDCDKALRMVEAAAQAGCECVKIQT
CEEEEEEHHHHEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEHH
HIIEDEMVPNDVVPGNAKESIWNIMSRCALTREEEVCIKRRTEELGMIFLSTPFSRAAAD
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCHHHHHH
QLESMGVTAYKIGSGECNNYPLIRHVASFGKPVILSTGMNDISSIEPAVAIFRELKTDYV
HHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCEE
LMHCTSLYPTPYEKVRLGALGDLKKAFPDAVLGLSDHSLGNYTCYAAVALGASVLEKHFT
EEEEHHCCCCCHHHEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
CDKLWPGPDVPISVDPGELKRLVEGTRAVHQAMGGHKEILPDEKPTIDFAYASVVAIRDI
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHCC
RAGDILSKDNIWVKRPGTGEILARDYERVLGRVAKRPLQKNAQLAWDDFDG
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]