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The map label for this gene is neuA [H]

Identifier: 78358297

GI number: 78358297

Start: 3255907

End: 3256605

Strand: Reverse

Name: neuA [H]

Synonym: Dde_3257

Alternate gene names: 78358297

Gene position: 3256605-3255907 (Counterclockwise)

Preceding gene: 78358298

Following gene: 78358296

Centisome position: 87.3

GC content: 49.5

Gene sequence:

>699_bases
ATGAGGCTTTTAGGTCTGATAACAGCCAGAGGCGGTTCTAAAAGGGTCCCCCGTAAAAATTTGCGGATCGTTGGCGGTAA
GCCGCTTATCGCTTGGACGGTCGAGGAGGCTTGCAAGTGTTCTCTGCTGGATTCGGTGGTTGTTTCTACGGATGATGAAG
AAATAGCCTCTGTCGCGCATCGTTTCGGGGCGTTGCGGCCTTTTATGCGTCCTGCCGATCTTGCCGGTGATGCTACGCCG
CATATTGACTGTGTTTTTCATGCTCTGGAATCCCTCAAGATGGTTGGTTTCAGCTCTTTTGATGCGGTAGTGCTTTTGCA
GCCGACTTCTCCTTTGCGATTGGCTGAAGATATTGAAGGCGTGGTCAATACGGCAATGAAAACCGGAGCGGAAGCTGTGG
TTTCTGTCAGTGAATCGGTTGAACATCCTTATTTTAGCCGGTTGATGGATGCTCAGGGGATTCTGTCTCCTGTTGTCTTG
CAAAACATGGCTTACCCCCGCAAGCAGGATCTGGAAAAAACATATTTTATAAATGGATCAATATACTTCAATACCGTTGA
GTCGTTGTGTCGTGACCGGACGTTTTATCCTGACAGGCTCCACGGGTATGTGGTGCCGCTGGAACGATCTCTGCAAGTGG
ATAGCGATTATGAGTTGAATATTGCGGATCTGCTGTTAAGCCAGCGCAGCCGCGGATGA

Upstream 100 bases:

>100_bases
CCCGGTCTGCGCAGTCAGGTGTTTTGGGAGTACAGCAGCAGCTTGTGCAAACTATGACAGCCGTGCGCCTGCAGTATATA
ACTTCCTGAGGTTTGAGTAT

Downstream 100 bases:

>100_bases
TTAGTGTGGAGGTAGCCGTGAACGAGGTAGTCATCGCCGGAAGAAAATTAGGTCCGCAGCATCCACCGCTTGTTATTGCG
GAAATCGGAATCAACCATGA

Product: CMP-N-acetlyneuraminic acid synthetase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRLLGLITARGGSKRVPRKNLRIVGGKPLIAWTVEEACKCSLLDSVVVSTDDEEIASVAHRFGALRPFMRPADLAGDATP
HIDCVFHALESLKMVGFSSFDAVVLLQPTSPLRLAEDIEGVVNTAMKTGAEAVVSVSESVEHPYFSRLMDAQGILSPVVL
QNMAYPRKQDLEKTYFINGSIYFNTVESLCRDRTFYPDRLHGYVVPLERSLQVDSDYELNIADLLLSQRSRG

Sequences:

>Translated_232_residues
MRLLGLITARGGSKRVPRKNLRIVGGKPLIAWTVEEACKCSLLDSVVVSTDDEEIASVAHRFGALRPFMRPADLAGDATP
HIDCVFHALESLKMVGFSSFDAVVLLQPTSPLRLAEDIEGVVNTAMKTGAEAVVSVSESVEHPYFSRLMDAQGILSPVVL
QNMAYPRKQDLEKTYFINGSIYFNTVESLCRDRTFYPDRLHGYVVPLERSLQVDSDYELNIADLLLSQRSRG
>Mature_232_residues
MRLLGLITARGGSKRVPRKNLRIVGGKPLIAWTVEEACKCSLLDSVVVSTDDEEIASVAHRFGALRPFMRPADLAGDATP
HIDCVFHALESLKMVGFSSFDAVVLLQPTSPLRLAEDIEGVVNTAMKTGAEAVVSVSESVEHPYFSRLMDAQGILSPVVL
QNMAYPRKQDLEKTYFINGSIYFNTVESLCRDRTFYPDRLHGYVVPLERSLQVDSDYELNIADLLLSQRSRG

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=221, Percent_Identity=29.8642533936652, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 25688; Mature: 25688

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLGLITARGGSKRVPRKNLRIVGGKPLIAWTVEEACKCSLLDSVVVSTDDEEIASVAH
CCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
RFGALRPFMRPADLAGDATPHIDCVFHALESLKMVGFSSFDAVVLLQPTSPLRLAEDIEG
HHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
VVNTAMKTGAEAVVSVSESVEHPYFSRLMDAQGILSPVVLQNMAYPRKQDLEKTYFINGS
HHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEECCE
IYFNTVESLCRDRTFYPDRLHGYVVPLERSLQVDSDYELNIADLLLSQRSRG
EEHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRLLGLITARGGSKRVPRKNLRIVGGKPLIAWTVEEACKCSLLDSVVVSTDDEEIASVAH
CCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
RFGALRPFMRPADLAGDATPHIDCVFHALESLKMVGFSSFDAVVLLQPTSPLRLAEDIEG
HHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
VVNTAMKTGAEAVVSVSESVEHPYFSRLMDAQGILSPVVLQNMAYPRKQDLEKTYFINGS
HHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEECCE
IYFNTVESLCRDRTFYPDRLHGYVVPLERSLQVDSDYELNIADLLLSQRSRG
EEHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]