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The map label for this gene is zraR [H]

Identifier: 78355650

GI number: 78355650

Start: 626794

End: 627153

Strand: Direct

Name: zraR [H]

Synonym: Dde_0603

Alternate gene names: 78355650

Gene position: 626794-627153 (Clockwise)

Preceding gene: 78355649

Following gene: 78355651

Centisome position: 16.8

GC content: 56.11

Gene sequence:

>360_bases
ATGGCGAATATACTGGTTCTGGACGATGTGATTGATGCCGGAGTGCTGATTAAACGGATTCTGGAGCGTAAAGGGCACAG
CGTGACGGCGTTTACCGAAGAGGAAGAAGCGCTGGCCCACGCCCGCGGCAACGAAGTTGATCTGGCCATTCTGGATATAA
AGCTGCGCCGCATGACAGGCGTCGAGGTGCTGGAGGAGCTGAAGAAGATACGGCCCGCGCTTAAAGCCATCATGCTTACG
GGGTATCCCACGCTGGAAACGGCCCGTGAATCCATGAAGCTGGGTGCCAATGAATACTGCGTGAAGCCCATCGACAAAGA
CGAGCTGGAAAGCAAGGTCAGCGATGTGCTGCGCGGCTGA

Upstream 100 bases:

>100_bases
CACATATTCTGTTAACGGCACCTGCGCCGGAGCGGGGCTGCCGCCACCGGCACCGCAGCGGCATGTGCGGGCCGCAGCCG
AAGAATTCTGGGAGCGCGAC

Downstream 100 bases:

>100_bases
CGCTTAAGGACGGCACAGGCCGTCTTTGCCCACGGGAGCAGATATGCCGCTTAAGGAACTCTTTCGGCACTGGACATATC
AGGCGTTTGCGCCGGGCACT

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MANILVLDDVIDAGVLIKRILERKGHSVTAFTEEEEALAHARGNEVDLAILDIKLRRMTGVEVLEELKKIRPALKAIMLT
GYPTLETARESMKLGANEYCVKPIDKDELESKVSDVLRG

Sequences:

>Translated_119_residues
MANILVLDDVIDAGVLIKRILERKGHSVTAFTEEEEALAHARGNEVDLAILDIKLRRMTGVEVLEELKKIRPALKAIMLT
GYPTLETARESMKLGANEYCVKPIDKDELESKVSDVLRG
>Mature_118_residues
ANILVLDDVIDAGVLIKRILERKGHSVTAFTEEEEALAHARGNEVDLAILDIKLRRMTGVEVLEELKKIRPALKAIMLTG
YPTLETARESMKLGANEYCVKPIDKDELESKVSDVLRG

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=33.0434782608696, Blast_Score=79, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 13244; Mature: 13112

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILVLDDVIDAGVLIKRILERKGHSVTAFTEEEEALAHARGNEVDLAILDIKLRRMTG
CCCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCEEEEEEHHHHHHHH
VEVLEELKKIRPALKAIMLTGYPTLETARESMKLGANEYCVKPIDKDELESKVSDVLRG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANILVLDDVIDAGVLIKRILERKGHSVTAFTEEEEALAHARGNEVDLAILDIKLRRMTG
CCEEEHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCEEEEEEHHHHHHHH
VEVLEELKKIRPALKAIMLTGYPTLETARESMKLGANEYCVKPIDKDELESKVSDVLRG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]