Click here to switch to the map view.

The map label for this gene is atoS [H]

Identifier: 78355649

GI number: 78355649

Start: 624475

End: 626610

Strand: Direct

Name: atoS [H]

Synonym: Dde_0602

Alternate gene names: 78355649

Gene position: 624475-626610 (Clockwise)

Preceding gene: 78355648

Following gene: 78355650

Centisome position: 16.74

GC content: 57.77

Gene sequence:

>2136_bases
GTGAGTCCTCTTACCCGGATGCGTTTCCGCAACAAGCTCAATGTGGGCATCACGCTGATAGTGCTGGCTGTTTCCGTGGT
GCTGGCCGTTGTTTCCATTCACATTTCCACATCAGAACTGCTGGCCGAATCGCGGCGCAGGGGGCTTGTGCTGGCCAGCA
ACCTTGCGTTGCGAGTGACAGACCCCATGCTGTCGGTGGATCTGCTGCGGCTCAAGACCATGGTGGACGAACTGTCCACA
GTGGATGAAGACGTAAGTTATGCCTTTGTGCTGGACAAGGCCAACAGGGTGCTGGTGCATTCGTTTGAAGATGGTTTTCC
CGTTGAGCTGCGCACCGCGAACCTGCTGCCCCACGGTGCCACCCGCCGTATCAGACTGGTGGATACGGGCACGGAACGCA
TCTATGATTTTGCCGTGGCGGTGCGCATCGGGCAGGAGCGTCTGGGCACCGTGCGCATGGGCCTTTCGCGTACCAAGGCT
CAGAAGGTCGTGCAGCGGCTTGTTTCCATCATTTCCACACTGACAGTGGTCTCTCTGCTGCTGGCTGTGCTTGTTTCCAC
GCATTTTGCCAGAAGAATAACCCACAGGCTGGGCATGCTGCGTGAATATGCAGAACAGATTGTACGCGGCAACATGGATG
TGACCGTGGGAGCCCACGACGCGCCGTACTGCTGGCAGCTTACACAATGCGGCTGCGACGACTGCCCCGCATACGGTGAT
ACGCTGCGGCGGTGCTGGCATGTGGCCAACACGCGCTGCATGGAAAACGGTCTGGCACATGACATGGCCGCGTCGTGTGC
CGACTGCCCCGTTCACGGCAGGCTGGCCGGTGACGAGTTGCAGGACCTTGCAGAAACATTTGACGTCATGGCGCTGTCGC
TGCGTCAGCATATGGCGGAACTGTGCGCGGCCGAGCAGGATCTTTCGCGTCAGCAGAAGCTGCTGCGTACCATCATTGAA
TCAACTCCCGACCTTGTTTCACTGGTCGGACGCGACGGAACATATCTGGCGGTCAACAGAGCCTTTGGCCACTGGGTGGG
GCATCCGGCGGAAGATCTGCCCGGCAGAAAAGACAGAGATATCTTTCCGCCGGAACTGGCCATACAGCGGGAACAGGAGC
ATGTGCGCATCCTTGCCACCGGTGTGACCGTAAGCCGCGAGGCAAGGCTGAAGGCGGCAGTGGACGGCAAGGAAGGCTGG
TTCCATGTGGTCAAGGTGCCGGTGACCGATGAAAACGGCAGAGTGACAGGCATTTTGTCAACAGCCCGTGATATTTCGGA
AATCCGCAGTTATCAGGACCAGCTGATCCATTCGCAGAAAATGGAATCGGTGGGCAGTCTGGCCGGCGGGGTGGCACATG
AAATAAACACGCCTCTGGGTATTATTCTGGGATACGCCCAGCTGTTGCAGGAAGATGTTCCCGAAGGTTCGCAGACGCAC
GAGGATCTGAAAATCATCGAACGGCAGGCCAAGTTCTGCCGCAAGGTCGTTGCCGACCTGCTGGGATTTTCACGGCATTC
GCAGAGTGAAAAAAAGGAGATGTGTTTCAACAACTCCATCATGGAAGTGGTGCAGCTGGTGCGGCACGCGTTTTCACTTG
AGAATGTGCGTATAGTCACCATGCTTGATGACCGTCTGCCTATTATCTACGGCGATCCGGGCAAATTGAAACAGGTATGG
ATGAATCTGCTTTCCAATGCGGTGCAGGCCAATGAAGGCGGCGGGCTGGTTGTGGTGCGTACCCGTCTTGATATCGACAA
CCTGACGGTAAGCGCCCTTTTTGCGGATACCGGTACCGGCATAAGCAAAGACAACATGGCATCGGTGTTTGACCCGTTTT
TCAGTACCAAACCTGTGGGCAAAGGAACAGGGCTGGGCCTGTCTGTTTCGTTCGGCATCATACGTGATCATGAGGGGGAA
ATAACAGTGCACAGCCCCCTGCCGCCGGATGTCATTCCGGACGAAGTGCGGGGTGACGAGCCGGCCGGTCCCGGTGCGCT
GTTTTCGGTTACGCTGCCGCTGGAACCGCCTGACTGGCCCCTGCCGGACGATTCCGCATCTGACGACACTGCTCCGGACG
ATTCGGAACGGCATACAGGCCGTAGTGACGGAGCAGGGGCTGCGCAGCGCGGCTGA

Upstream 100 bases:

>100_bases
CCAATGCGGGCATACGCGGTATAATTCCCGCTGCCGATGCCGATTACGCCCCCATAAGGGAGCTGATGTCCAAACTTGAT
CTGTACGGGGAGGTGGACTG

Downstream 100 bases:

>100_bases
AACTGCACCGGCAATTGTCCGGTCATGCCGCTGACGGCGGCTTATGTCTGTCTGGATGATATCCGTGAAACCGTGTAGGA
TTGCACATATTCTGTTAACG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MSPLTRMRFRNKLNVGITLIVLAVSVVLAVVSIHISTSELLAESRRRGLVLASNLALRVTDPMLSVDLLRLKTMVDELST
VDEDVSYAFVLDKANRVLVHSFEDGFPVELRTANLLPHGATRRIRLVDTGTERIYDFAVAVRIGQERLGTVRMGLSRTKA
QKVVQRLVSIISTLTVVSLLLAVLVSTHFARRITHRLGMLREYAEQIVRGNMDVTVGAHDAPYCWQLTQCGCDDCPAYGD
TLRRCWHVANTRCMENGLAHDMAASCADCPVHGRLAGDELQDLAETFDVMALSLRQHMAELCAAEQDLSRQQKLLRTIIE
STPDLVSLVGRDGTYLAVNRAFGHWVGHPAEDLPGRKDRDIFPPELAIQREQEHVRILATGVTVSREARLKAAVDGKEGW
FHVVKVPVTDENGRVTGILSTARDISEIRSYQDQLIHSQKMESVGSLAGGVAHEINTPLGIILGYAQLLQEDVPEGSQTH
EDLKIIERQAKFCRKVVADLLGFSRHSQSEKKEMCFNNSIMEVVQLVRHAFSLENVRIVTMLDDRLPIIYGDPGKLKQVW
MNLLSNAVQANEGGGLVVVRTRLDIDNLTVSALFADTGTGISKDNMASVFDPFFSTKPVGKGTGLGLSVSFGIIRDHEGE
ITVHSPLPPDVIPDEVRGDEPAGPGALFSVTLPLEPPDWPLPDDSASDDTAPDDSERHTGRSDGAGAAQRG

Sequences:

>Translated_711_residues
MSPLTRMRFRNKLNVGITLIVLAVSVVLAVVSIHISTSELLAESRRRGLVLASNLALRVTDPMLSVDLLRLKTMVDELST
VDEDVSYAFVLDKANRVLVHSFEDGFPVELRTANLLPHGATRRIRLVDTGTERIYDFAVAVRIGQERLGTVRMGLSRTKA
QKVVQRLVSIISTLTVVSLLLAVLVSTHFARRITHRLGMLREYAEQIVRGNMDVTVGAHDAPYCWQLTQCGCDDCPAYGD
TLRRCWHVANTRCMENGLAHDMAASCADCPVHGRLAGDELQDLAETFDVMALSLRQHMAELCAAEQDLSRQQKLLRTIIE
STPDLVSLVGRDGTYLAVNRAFGHWVGHPAEDLPGRKDRDIFPPELAIQREQEHVRILATGVTVSREARLKAAVDGKEGW
FHVVKVPVTDENGRVTGILSTARDISEIRSYQDQLIHSQKMESVGSLAGGVAHEINTPLGIILGYAQLLQEDVPEGSQTH
EDLKIIERQAKFCRKVVADLLGFSRHSQSEKKEMCFNNSIMEVVQLVRHAFSLENVRIVTMLDDRLPIIYGDPGKLKQVW
MNLLSNAVQANEGGGLVVVRTRLDIDNLTVSALFADTGTGISKDNMASVFDPFFSTKPVGKGTGLGLSVSFGIIRDHEGE
ITVHSPLPPDVIPDEVRGDEPAGPGALFSVTLPLEPPDWPLPDDSASDDTAPDDSERHTGRSDGAGAAQRG
>Mature_710_residues
SPLTRMRFRNKLNVGITLIVLAVSVVLAVVSIHISTSELLAESRRRGLVLASNLALRVTDPMLSVDLLRLKTMVDELSTV
DEDVSYAFVLDKANRVLVHSFEDGFPVELRTANLLPHGATRRIRLVDTGTERIYDFAVAVRIGQERLGTVRMGLSRTKAQ
KVVQRLVSIISTLTVVSLLLAVLVSTHFARRITHRLGMLREYAEQIVRGNMDVTVGAHDAPYCWQLTQCGCDDCPAYGDT
LRRCWHVANTRCMENGLAHDMAASCADCPVHGRLAGDELQDLAETFDVMALSLRQHMAELCAAEQDLSRQQKLLRTIIES
TPDLVSLVGRDGTYLAVNRAFGHWVGHPAEDLPGRKDRDIFPPELAIQREQEHVRILATGVTVSREARLKAAVDGKEGWF
HVVKVPVTDENGRVTGILSTARDISEIRSYQDQLIHSQKMESVGSLAGGVAHEINTPLGIILGYAQLLQEDVPEGSQTHE
DLKIIERQAKFCRKVVADLLGFSRHSQSEKKEMCFNNSIMEVVQLVRHAFSLENVRIVTMLDDRLPIIYGDPGKLKQVWM
NLLSNAVQANEGGGLVVVRTRLDIDNLTVSALFADTGTGISKDNMASVFDPFFSTKPVGKGTGLGLSVSFGIIRDHEGEI
TVHSPLPPDVIPDEVRGDEPAGPGALFSVTLPLEPPDWPLPDDSASDDTAPDDSERHTGRSDGAGAAQRG

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=405, Percent_Identity=28.641975308642, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=31.6872427983539, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI48994928, Length=427, Percent_Identity=26.2295081967213, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI1790300, Length=229, Percent_Identity=34.061135371179, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=28.9156626506024, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=29.7619047619048, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=25.6317689530686, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1789149, Length=209, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=395, Percent_Identity=21.7721518987342, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=24.3027888446215, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78055; Mature: 77924

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00041 HTH_ARAC_FAMILY_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLTRMRFRNKLNVGITLIVLAVSVVLAVVSIHISTSELLAESRRRGLVLASNLALRVT
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCEEEEE
DPMLSVDLLRLKTMVDELSTVDEDVSYAFVLDKANRVLVHSFEDGFPVELRTANLLPHGA
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCEEEEECCCCCCCC
TRRIRLVDTGTERIYDFAVAVRIGQERLGTVRMGLSRTKAQKVVQRLVSIISTLTVVSLL
CCEEEEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLVSTHFARRITHRLGMLREYAEQIVRGNMDVTVGAHDAPYCWQLTQCGCDDCPAYGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEHHHCCCCCCCCHHH
TLRRCWHVANTRCMENGLAHDMAASCADCPVHGRLAGDELQDLAETFDVMALSLRQHMAE
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LCAAEQDLSRQQKLLRTIIESTPDLVSLVGRDGTYLAVNRAFGHWVGHPAEDLPGRKDRD
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECHHHHHCCCCHHHCCCCCCCC
IFPPELAIQREQEHVRILATGVTVSREARLKAAVDGKEGWFHVVKVPVTDENGRVTGILS
CCCCHHHHHCCCCCEEEEEECCEECCCCHHHEEECCCCCCEEEEEEEEECCCCCEEEEHH
TARDISEIRSYQDQLIHSQKMESVGSLAGGVAHEINTPLGIILGYAQLLQEDVPEGSQTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
EDLKIIERQAKFCRKVVADLLGFSRHSQSEKKEMCFNNSIMEVVQLVRHAFSLENVRIVT
HHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEE
MLDDRLPIIYGDPGKLKQVWMNLLSNAVQANEGGGLVVVRTRLDIDNLTVSALFADTGTG
EECCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCC
ISKDNMASVFDPFFSTKPVGKGTGLGLSVSFGIIRDHEGEITVHSPLPPDVIPDEVRGDE
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCCHHCCCCC
PAGPGALFSVTLPLEPPDWPLPDDSASDDTAPDDSERHTGRSDGAGAAQRG
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPLTRMRFRNKLNVGITLIVLAVSVVLAVVSIHISTSELLAESRRRGLVLASNLALRVT
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCEEEEE
DPMLSVDLLRLKTMVDELSTVDEDVSYAFVLDKANRVLVHSFEDGFPVELRTANLLPHGA
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCEEEEECCCCCCCC
TRRIRLVDTGTERIYDFAVAVRIGQERLGTVRMGLSRTKAQKVVQRLVSIISTLTVVSLL
CCEEEEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLVSTHFARRITHRLGMLREYAEQIVRGNMDVTVGAHDAPYCWQLTQCGCDDCPAYGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEHHHCCCCCCCCHHH
TLRRCWHVANTRCMENGLAHDMAASCADCPVHGRLAGDELQDLAETFDVMALSLRQHMAE
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LCAAEQDLSRQQKLLRTIIESTPDLVSLVGRDGTYLAVNRAFGHWVGHPAEDLPGRKDRD
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECHHHHHCCCCHHHCCCCCCCC
IFPPELAIQREQEHVRILATGVTVSREARLKAAVDGKEGWFHVVKVPVTDENGRVTGILS
CCCCHHHHHCCCCCEEEEEECCEECCCCHHHEEECCCCCCEEEEEEEEECCCCCEEEEHH
TARDISEIRSYQDQLIHSQKMESVGSLAGGVAHEINTPLGIILGYAQLLQEDVPEGSQTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
EDLKIIERQAKFCRKVVADLLGFSRHSQSEKKEMCFNNSIMEVVQLVRHAFSLENVRIVT
HHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEE
MLDDRLPIIYGDPGKLKQVWMNLLSNAVQANEGGGLVVVRTRLDIDNLTVSALFADTGTG
EECCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCC
ISKDNMASVFDPFFSTKPVGKGTGLGLSVSFGIIRDHEGEITVHSPLPPDVIPDEVRGDE
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCCHHCCCCC
PAGPGALFSVTLPLEPPDWPLPDDSASDDTAPDDSERHTGRSDGAGAAQRG
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]