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The map label for this gene is ptxB [H]

Identifier: 78355648

GI number: 78355648

Start: 623459

End: 624478

Strand: Direct

Name: ptxB [H]

Synonym: Dde_0601

Alternate gene names: 78355648

Gene position: 623459-624478 (Clockwise)

Preceding gene: 78355647

Following gene: 78355649

Centisome position: 16.71

GC content: 59.22

Gene sequence:

>1020_bases
TTGGAGAACTCAGACAGAAGAAAGGCCGCGCGGGCCGGCGGAGGCGCTCTGTCCGCAGAAGCAGGGGAAAGCGCTCTGCG
CCGTATTTTTTTCAGGCAGCCGGAACTTTTTGCGTTCCTGCTGCTTTTCTGCGTTCTGGCGGGGGGCTGCGGCGAAAATG
AAGAAGTGGTGCGGGTGGACCTGTCGCACCGCGAACGTATTGTGGTGGCCAAACCGGCAGAGGCGGTCACCTACGCCTAC
CTGCCCCAGTATTCGCACACCACGTCCTACACGCGGCATAACCCGCTGGTGGAATATCTTGAGCGGGAATCGGGCCTTAC
CATGCGTCAGGTGTTTCCCGACACGTTTGAAGAACACACCCGCATGGTTGAGCGCGGCGAGATAGATATCTCTTTTTCCA
ATCCGTTCACATATGTCCGGCTGGCGCAGAAAGGGGCCACCGCTTTTGCCAGAGTCATCGAACCGTCGGGCAGACCTTTT
TTCCGCGGGCAGATAATCGCACGCATCGACAGCGGCATACGGCGGCTTGAAGACTGCGAGGGCAAACGCTGGATAGCGGT
GGATCCGCTTTCCGCGGGCGGGTATCTGTTTGCGCTGGGTATGTTCCACGACATGGGGCTGGATACGGATGATTTTGCGG
CCGTGGATTTTGCTCCGGGCCCCGGAGGCAAGCAGGAAAAAGCTGTCCTTGCGGTGTACGCGGGCAAGTACGACTTTGCT
TCCATACGGGAAGGCACGCTGGATATCGTGCGTGACAAAATAGATCCGGAACGCATACGGGTTGTCGCAACCACACAGGC
GTATCCCGGCTGGGTGTATGCCGCGCGCAAGGGGCTGGACCCCGCGGTGGTCGACCGCATACGCAATGCCATGTTCAGGC
TGTCCATGGAAGAACCCGAAGGCGGGCGCATACTGGCCAATGCGGGCATACGCGGTATAATTCCCGCTGCCGATGCCGAT
TACGCCCCCATAAGGGAGCTGATGTCCAAACTTGATCTGTACGGGGAGGTGGACTGGTGA

Upstream 100 bases:

>100_bases
AAACGGACACCGTATAATGCCGCAGCGTGCCGGTTGCGGCTGCGCTGCGCAGGGGCTGACGGAGCGGATATACTGATTCG
GACTGAGGGCAGGTGACGGT

Downstream 100 bases:

>100_bases
GTCCTCTTACCCGGATGCGTTTCCGCAACAAGCTCAATGTGGGCATCACGCTGATAGTGCTGGCTGTTTCCGTGGTGCTG
GCCGTTGTTTCCATTCACAT

Product: phosphonate-binding periplasmic protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MENSDRRKAARAGGGALSAEAGESALRRIFFRQPELFAFLLLFCVLAGGCGENEEVVRVDLSHRERIVVAKPAEAVTYAY
LPQYSHTTSYTRHNPLVEYLERESGLTMRQVFPDTFEEHTRMVERGEIDISFSNPFTYVRLAQKGATAFARVIEPSGRPF
FRGQIIARIDSGIRRLEDCEGKRWIAVDPLSAGGYLFALGMFHDMGLDTDDFAAVDFAPGPGGKQEKAVLAVYAGKYDFA
SIREGTLDIVRDKIDPERIRVVATTQAYPGWVYAARKGLDPAVVDRIRNAMFRLSMEEPEGGRILANAGIRGIIPAADAD
YAPIRELMSKLDLYGEVDW

Sequences:

>Translated_339_residues
MENSDRRKAARAGGGALSAEAGESALRRIFFRQPELFAFLLLFCVLAGGCGENEEVVRVDLSHRERIVVAKPAEAVTYAY
LPQYSHTTSYTRHNPLVEYLERESGLTMRQVFPDTFEEHTRMVERGEIDISFSNPFTYVRLAQKGATAFARVIEPSGRPF
FRGQIIARIDSGIRRLEDCEGKRWIAVDPLSAGGYLFALGMFHDMGLDTDDFAAVDFAPGPGGKQEKAVLAVYAGKYDFA
SIREGTLDIVRDKIDPERIRVVATTQAYPGWVYAARKGLDPAVVDRIRNAMFRLSMEEPEGGRILANAGIRGIIPAADAD
YAPIRELMSKLDLYGEVDW
>Mature_339_residues
MENSDRRKAARAGGGALSAEAGESALRRIFFRQPELFAFLLLFCVLAGGCGENEEVVRVDLSHRERIVVAKPAEAVTYAY
LPQYSHTTSYTRHNPLVEYLERESGLTMRQVFPDTFEEHTRMVERGEIDISFSNPFTYVRLAQKGATAFARVIEPSGRPF
FRGQIIARIDSGIRRLEDCEGKRWIAVDPLSAGGYLFALGMFHDMGLDTDDFAAVDFAPGPGGKQEKAVLAVYAGKYDFA
SIREGTLDIVRDKIDPERIRVVATTQAYPGWVYAARKGLDPAVVDRIRNAMFRLSMEEPEGGRILANAGIRGIIPAADAD
YAPIRELMSKLDLYGEVDW

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 37739; Mature: 37739

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSDRRKAARAGGGALSAEAGESALRRIFFRQPELFAFLLLFCVLAGGCGENEEVVRVD
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEE
LSHRERIVVAKPAEAVTYAYLPQYSHTTSYTRHNPLVEYLERESGLTMRQVFPDTFEEHT
CCCCCEEEEECCCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCHHHHHHH
RMVERGEIDISFSNPFTYVRLAQKGATAFARVIEPSGRPFFRGQIIARIDSGIRRLEDCE
HHHHCCCEEEEECCCEEEEEEHHHCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCC
GKRWIAVDPLSAGGYLFALGMFHDMGLDTDDFAAVDFAPGPGGKQEKAVLAVYAGKYDFA
CCEEEEECCCCCCCHHHEEHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHH
SIREGTLDIVRDKIDPERIRVVATTQAYPGWVYAARKGLDPAVVDRIRNAMFRLSMEEPE
HHCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHEEEECCCCC
GGRILANAGIRGIIPAADADYAPIRELMSKLDLYGEVDW
CCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MENSDRRKAARAGGGALSAEAGESALRRIFFRQPELFAFLLLFCVLAGGCGENEEVVRVD
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEE
LSHRERIVVAKPAEAVTYAYLPQYSHTTSYTRHNPLVEYLERESGLTMRQVFPDTFEEHT
CCCCCEEEEECCCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCHHHHHHH
RMVERGEIDISFSNPFTYVRLAQKGATAFARVIEPSGRPFFRGQIIARIDSGIRRLEDCE
HHHHCCCEEEEECCCEEEEEEHHHCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCC
GKRWIAVDPLSAGGYLFALGMFHDMGLDTDDFAAVDFAPGPGGKQEKAVLAVYAGKYDFA
CCEEEEECCCCCCCHHHEEHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHH
SIREGTLDIVRDKIDPERIRVVATTQAYPGWVYAARKGLDPAVVDRIRNAMFRLSMEEPE
HHCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHEEEECCCCC
GGRILANAGIRGIIPAADADYAPIRELMSKLDLYGEVDW
CCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]