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The map label for this gene is speA [H]

Identifier: 78355618

GI number: 78355618

Start: 595140

End: 597092

Strand: Direct

Name: speA [H]

Synonym: Dde_0571

Alternate gene names: 78355618

Gene position: 595140-597092 (Clockwise)

Preceding gene: 78355617

Following gene: 78355619

Centisome position: 15.95

GC content: 57.3

Gene sequence:

>1953_bases
ATGAAACGGGGTATTTATGAGGATCAGAGATTGGCACGTAAGCACACTCTGCAACGGTGGAGCGCCGAAGACTCCGCCGA
ACTCTATGGCATCCGCAACTGGGGTGCCGGGTACTTCGATGTTTCCGCCGAAGGCGACGTCGTGGTGTATCCTTTCGGGA
GGTCGCATAAGCTGAACGTCAGCGTTCCGGACATCATCCGGGGCATGAAGGAGCGCGGGCTTGATATGCCTGTGCTGCTT
CGCATCGAGAACATTCTCGAATCACGCATCTCCCTTCTTCACAAATCATTCCGCAACGCCATCGAATCGCTCGGTTATCA
GGGCGGCTACCGGGGCGTTTTTCCCATCAAGGTCAATCAGCAGCAGCAGGTTATCGAAAAGATAGCCACATACGGCTCCA
TGTACCATCACGGTCTGGAGGTCGGTTCCAAGGCGGAGCTTATCGCCGCCATCTCGCAGGCGCAGGATAAAGAAGCGTGC
ATTGTCTGCAACGGGTACAAGGACGAGGAGTTCATTGACCTGGGGCTGCATGCCGTCCGCATGGGGTTCAAGTGCTTTTT
TGTGCTTGAAATGCCGCGTGAGCTTGAGCTTATTCTGCGGCGTTCGCAGCAGATGGGTGTGCGTCCGCTTATCGGCACCC
GTGTCAAGCTTGCCAGCAAGGCGGGCGGTCACTGGAGCGATTCCGGCGGCGAGCTGTCCACTTTCGGCCTGACCACGGCG
CAGATAATGGACGTGGTGGACCGGCTGCAGAAAGAGGACATGCTCGACTGCTTCCGCCTGCTGCATTACCACCTCGGTTC
GCAGGTGCCCAATATCCGCGATATCCGCAGTGCCGTAATGGAAGCCACCCGCGTTTATGCAGGTCTGGTGTCCGAAGGTG
CCGCCATGGGCTATCTTGACCTGGGCGGCGGCCTTGCCGTGGATTACGACGGGTCGCATACCAATTTCGTTTCCAGCCGC
AACTACACGCAGGACGAGTACTGCACGGACATTGTGGAAGCCGTCATGAGCATTCTGGACGAAACAGGTGTGCCGCATCC
GCATATCATCACGGAATCCGGCCGGGCCACCGTGGCGTATTATTCCATGCTGCTTTTTAACATCCTTGATGTGAGCGGCG
CCGAAGCCTTTCCCGACAATCTGCCGGATACACTGGATGAAAGTGAACCGGAAATGATCCGCAACCTGTTCGAGGCGTTC
AGAGGGCTTACGCTGCGCAACCTGCAGGAATGCTATAACGACGCGTTGTACTACCGCGACGAAATCCGCCGTAATTTTCT
GGACGGACGGGTGACGCTGCGTCAGCGCACGCTGGGCGAGCGGATTTTCTGGGCACTCATGCGGCGTGTGGCGGAGGAAA
AAGATAAACTCCGTCATGTGCCCAAAGAACTTGCCGAGATAGACCGTGTACTGGCCGATGTCTATTACGGCAACTTCAGT
GTGTTCCAGTCGCTGCCCGACTCTTGGGCCATCGAACAGCTGTTTCCTGTCATGCCGGTTCACAGGCTCAGGGAATTTCC
CGACCGTCCGGCCATTCTTTCGGACATCACCTGTGACAGTGACGGACGCATAGACCGCTTCATCGATCCGCAAGGGGTGC
GCAATACCATTGACCTGCATTCCCTTAACGGCGAGGAGTATTATCTGGGCGTCTTTCTGGTGGGCGCGTATCAGGAAACG
CTGGGCGACCTGCACAACCTGCTGGGCGACACCAACGTGGTCAGCATCCGCGTGGAAGAGGACGGCAGCATTGAATACCG
GCGTGAACTGCTTGGTGATTCCGTGGCCGATGTGCTTTCCAGCGTGGAATACGACCCGAGGCGCATCATGGAACAGCTGC
GCGACACGGCGGAACAGGCAGTGCGCGAGGGGCGCATCACCCCTTCCGAAAGGTACGGCATTTTGCAGGCCTACGAAAAC
GGTCTGCGCGGATACACCTATTTCGAACGATAG

Upstream 100 bases:

>100_bases
GCCTGAATGGCAGGGTGCGGTGCGCGGCGTATATGCAGCCGGCAGCGCGCAGTATGGCAAAGGTCGGGCGCGCCCTGCGG
GGCGGCCTGTGCAGGTAACA

Downstream 100 bases:

>100_bases
AAGTGCACGCCGCATGATGCGGCTGCAAGGAGATGCCCTATGGCAAAAGTGCTCATTCTCGGCGCCGGCGGTGTCGGCTC
TGTTGCCGCGCATAAATGCG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MKRGIYEDQRLARKHTLQRWSAEDSAELYGIRNWGAGYFDVSAEGDVVVYPFGRSHKLNVSVPDIIRGMKERGLDMPVLL
RIENILESRISLLHKSFRNAIESLGYQGGYRGVFPIKVNQQQQVIEKIATYGSMYHHGLEVGSKAELIAAISQAQDKEAC
IVCNGYKDEEFIDLGLHAVRMGFKCFFVLEMPRELELILRRSQQMGVRPLIGTRVKLASKAGGHWSDSGGELSTFGLTTA
QIMDVVDRLQKEDMLDCFRLLHYHLGSQVPNIRDIRSAVMEATRVYAGLVSEGAAMGYLDLGGGLAVDYDGSHTNFVSSR
NYTQDEYCTDIVEAVMSILDETGVPHPHIITESGRATVAYYSMLLFNILDVSGAEAFPDNLPDTLDESEPEMIRNLFEAF
RGLTLRNLQECYNDALYYRDEIRRNFLDGRVTLRQRTLGERIFWALMRRVAEEKDKLRHVPKELAEIDRVLADVYYGNFS
VFQSLPDSWAIEQLFPVMPVHRLREFPDRPAILSDITCDSDGRIDRFIDPQGVRNTIDLHSLNGEEYYLGVFLVGAYQET
LGDLHNLLGDTNVVSIRVEEDGSIEYRRELLGDSVADVLSSVEYDPRRIMEQLRDTAEQAVREGRITPSERYGILQAYEN
GLRGYTYFER

Sequences:

>Translated_650_residues
MKRGIYEDQRLARKHTLQRWSAEDSAELYGIRNWGAGYFDVSAEGDVVVYPFGRSHKLNVSVPDIIRGMKERGLDMPVLL
RIENILESRISLLHKSFRNAIESLGYQGGYRGVFPIKVNQQQQVIEKIATYGSMYHHGLEVGSKAELIAAISQAQDKEAC
IVCNGYKDEEFIDLGLHAVRMGFKCFFVLEMPRELELILRRSQQMGVRPLIGTRVKLASKAGGHWSDSGGELSTFGLTTA
QIMDVVDRLQKEDMLDCFRLLHYHLGSQVPNIRDIRSAVMEATRVYAGLVSEGAAMGYLDLGGGLAVDYDGSHTNFVSSR
NYTQDEYCTDIVEAVMSILDETGVPHPHIITESGRATVAYYSMLLFNILDVSGAEAFPDNLPDTLDESEPEMIRNLFEAF
RGLTLRNLQECYNDALYYRDEIRRNFLDGRVTLRQRTLGERIFWALMRRVAEEKDKLRHVPKELAEIDRVLADVYYGNFS
VFQSLPDSWAIEQLFPVMPVHRLREFPDRPAILSDITCDSDGRIDRFIDPQGVRNTIDLHSLNGEEYYLGVFLVGAYQET
LGDLHNLLGDTNVVSIRVEEDGSIEYRRELLGDSVADVLSSVEYDPRRIMEQLRDTAEQAVREGRITPSERYGILQAYEN
GLRGYTYFER
>Mature_650_residues
MKRGIYEDQRLARKHTLQRWSAEDSAELYGIRNWGAGYFDVSAEGDVVVYPFGRSHKLNVSVPDIIRGMKERGLDMPVLL
RIENILESRISLLHKSFRNAIESLGYQGGYRGVFPIKVNQQQQVIEKIATYGSMYHHGLEVGSKAELIAAISQAQDKEAC
IVCNGYKDEEFIDLGLHAVRMGFKCFFVLEMPRELELILRRSQQMGVRPLIGTRVKLASKAGGHWSDSGGELSTFGLTTA
QIMDVVDRLQKEDMLDCFRLLHYHLGSQVPNIRDIRSAVMEATRVYAGLVSEGAAMGYLDLGGGLAVDYDGSHTNFVSSR
NYTQDEYCTDIVEAVMSILDETGVPHPHIITESGRATVAYYSMLLFNILDVSGAEAFPDNLPDTLDESEPEMIRNLFEAF
RGLTLRNLQECYNDALYYRDEIRRNFLDGRVTLRQRTLGERIFWALMRRVAEEKDKLRHVPKELAEIDRVLADVYYGNFS
VFQSLPDSWAIEQLFPVMPVHRLREFPDRPAILSDITCDSDGRIDRFIDPQGVRNTIDLHSLNGEEYYLGVFLVGAYQET
LGDLHNLLGDTNVVSIRVEEDGSIEYRRELLGDSVADVLSSVEYDPRRIMEQLRDTAEQAVREGRITPSERYGILQAYEN
GLRGYTYFER

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=627, Percent_Identity=38.5964912280702, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 73918; Mature: 73918

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGIYEDQRLARKHTLQRWSAEDSAELYGIRNWGAGYFDVSAEGDVVVYPFGRSHKLNV
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCEEEEECCCCCEECC
SVPDIIRGMKERGLDMPVLLRIENILESRISLLHKSFRNAIESLGYQGGYRGVFPIKVNQ
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
QQQVIEKIATYGSMYHHGLEVGSKAELIAAISQAQDKEACIVCNGYKDEEFIDLGLHAVR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
MGFKCFFVLEMPRELELILRRSQQMGVRPLIGTRVKLASKAGGHWSDSGGELSTFGLTTA
HCCCEEEEEECCHHHHHHHHHHHHCCCCCHHCCHHHHHHCCCCCCCCCCCCEEECCCHHH
QIMDVVDRLQKEDMLDCFRLLHYHLGSQVPNIRDIRSAVMEATRVYAGLVSEGAAMGYLD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LGGGLAVDYDGSHTNFVSSRNYTQDEYCTDIVEAVMSILDETGVPHPHIITESGRATVAY
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHH
YSMLLFNILDVSGAEAFPDNLPDTLDESEPEMIRNLFEAFRGLTLRNLQECYNDALYYRD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EIRRNFLDGRVTLRQRTLGERIFWALMRRVAEEKDKLRHVPKELAEIDRVLADVYYGNFS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VFQSLPDSWAIEQLFPVMPVHRLREFPDRPAILSDITCDSDGRIDRFIDPQGVRNTIDLH
HHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEE
SLNGEEYYLGVFLVGAYQETLGDLHNLLGDTNVVSIRVEEDGSIEYRRELLGDSVADVLS
ECCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHH
SVEYDPRRIMEQLRDTAEQAVREGRITPSERYGILQAYENGLRGYTYFER
HCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKRGIYEDQRLARKHTLQRWSAEDSAELYGIRNWGAGYFDVSAEGDVVVYPFGRSHKLNV
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCEEEEECCCCCEECC
SVPDIIRGMKERGLDMPVLLRIENILESRISLLHKSFRNAIESLGYQGGYRGVFPIKVNQ
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
QQQVIEKIATYGSMYHHGLEVGSKAELIAAISQAQDKEACIVCNGYKDEEFIDLGLHAVR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
MGFKCFFVLEMPRELELILRRSQQMGVRPLIGTRVKLASKAGGHWSDSGGELSTFGLTTA
HCCCEEEEEECCHHHHHHHHHHHHCCCCCHHCCHHHHHHCCCCCCCCCCCCEEECCCHHH
QIMDVVDRLQKEDMLDCFRLLHYHLGSQVPNIRDIRSAVMEATRVYAGLVSEGAAMGYLD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LGGGLAVDYDGSHTNFVSSRNYTQDEYCTDIVEAVMSILDETGVPHPHIITESGRATVAY
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHH
YSMLLFNILDVSGAEAFPDNLPDTLDESEPEMIRNLFEAFRGLTLRNLQECYNDALYYRD
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EIRRNFLDGRVTLRQRTLGERIFWALMRRVAEEKDKLRHVPKELAEIDRVLADVYYGNFS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VFQSLPDSWAIEQLFPVMPVHRLREFPDRPAILSDITCDSDGRIDRFIDPQGVRNTIDLH
HHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEE
SLNGEEYYLGVFLVGAYQETLGDLHNLLGDTNVVSIRVEEDGSIEYRRELLGDSVADVLS
ECCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHH
SVEYDPRRIMEQLRDTAEQAVREGRITPSERYGILQAYENGLRGYTYFER
HCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]