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The map label for this gene is 78355619

Identifier: 78355619

GI number: 78355619

Start: 597132

End: 598328

Strand: Direct

Name: 78355619

Synonym: Dde_0572

Alternate gene names: NA

Gene position: 597132-598328 (Clockwise)

Preceding gene: 78355618

Following gene: 78355620

Centisome position: 16.01

GC content: 56.06

Gene sequence:

>1197_bases
ATGGCAAAAGTGCTCATTCTCGGCGCCGGCGGTGTCGGCTCTGTTGCCGCGCATAAATGCGCGCAGGCCCCGGAGATTTT
TTCAGAAATCGTGCTGGCAAGCCGCACGGTCTCCAAATGCGTCGCCATTGCCGATTCCATCCGGCAGCGCACCGGCCGCA
CCATAGAAACCGCTCAGGTGGATGCCGACAACGTGGCGGAAATGGTGCAGCTGATCAACGCGGTAAAGCCTGATCTGGTG
GTGAACCTCGCCCTGCCGTATCAGGATCTGCCCGTCATGGATGCCTGCCTTGAAACCGGCGTCAATTATCTGGACACGGC
CAACTACGAACCGCCGGACACTGCCCGTTTTGAATACAAGTGGCAGTGGGAGTATCAGGACCGCTTCAGGGAAAAAGGGC
TCATGGCACTGCTGGGCAGCGGGTTTGATCCCGGTGTGACCAACGTGTTTGCCGCCCATGCCGTCAAGCACCATTTTGAC
GAGATTCATGTTCTCGACATTATCGACTGCAATGCCGGTGATCACGGCTATCCTTTTGCCACCAATTTCAATCCGGAAAT
CAATATCCGTGAAGTAACCGCCAGAGGGCGCTACTGGGAGCGCGGCGAATGGGTGGAGACCGATCCTCTTTCGTGGAGCA
TGCAGTATGATTTCCCCGAGGGCATCGGCAGGAAAAAGTGCTTTCTCATGTATCACGAAGAGCTTGAGTCGCTGGTGCGC
AACCTGCCCGGCATCAGGCGCGCCCGGTTCTGGATGACGTTTTCAGACAACTATCTCAACCACCTGAAGGTGCTTGAAAA
TGTTGGTATGACCCGCATTGATCCCGTGCGCTATAACGGGCAGGACATTGTGCCGCTGCAGTTTCTCAAGGAACTGTTGC
CCGATCCCGCATCGCTGGGCCCGCGTACCAAAGGCAAGACCTGCATCGGCAACGTGATGCACGGTGTCAAGGACGGCAAG
GAAAAGAGCCTGTACGTATACAACGTGTGTGATCATGAAGAATGCTACCGCGAGGTAGGTTCTCAGGCCATTTCCTACAC
CACCGGCGTGCCCGCGATGATAGGTGCCATGATGATGGTCACCGGCAAGTGGCAGGGCAGCGGCGTGTTTAACATGGAAC
AGCTTGACCCTGACCCGTTCATGGAAGAGCTCAACAAGCGTGGTCTGCCGTGGAAAGAGGTTATCTTGAAAGGTTAG

Upstream 100 bases:

>100_bases
GTACGGCATTTTGCAGGCCTACGAAAACGGTCTGCGCGGATACACCTATTTCGAACGATAGAAGTGCACGCCGCATGATG
CGGCTGCAAGGAGATGCCCT

Downstream 100 bases:

>100_bases
GCATCGGAAGGGTGCCCTCGCCGTGCTTTGTGGTGGACGAGGGCCTTCTGAGCCGGAATCTTGCCGTGCTGGACACGGTT
CAGCAGCGCACCGGTGCCAG

Product: saccharopine dehydrogenase

Products: L-lysine; 2-oxoglutarate; NADH; H+

Alternate protein names: Carboxynorspermidine Dehydrogenase; Saccharopine Dehydrogenase-Like Protein; Saccharopine Dehydrogenase Family Protein; Acyl Carrier Protein; Carboxynorspermide Hydratase

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAKVLILGAGGVGSVAAHKCAQAPEIFSEIVLASRTVSKCVAIADSIRQRTGRTIETAQVDADNVAEMVQLINAVKPDLV
VNLALPYQDLPVMDACLETGVNYLDTANYEPPDTARFEYKWQWEYQDRFREKGLMALLGSGFDPGVTNVFAAHAVKHHFD
EIHVLDIIDCNAGDHGYPFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMQYDFPEGIGRKKCFLMYHEELESLVR
NLPGIRRARFWMTFSDNYLNHLKVLENVGMTRIDPVRYNGQDIVPLQFLKELLPDPASLGPRTKGKTCIGNVMHGVKDGK
EKSLYVYNVCDHEECYREVGSQAISYTTGVPAMIGAMMMVTGKWQGSGVFNMEQLDPDPFMEELNKRGLPWKEVILKG

Sequences:

>Translated_398_residues
MAKVLILGAGGVGSVAAHKCAQAPEIFSEIVLASRTVSKCVAIADSIRQRTGRTIETAQVDADNVAEMVQLINAVKPDLV
VNLALPYQDLPVMDACLETGVNYLDTANYEPPDTARFEYKWQWEYQDRFREKGLMALLGSGFDPGVTNVFAAHAVKHHFD
EIHVLDIIDCNAGDHGYPFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMQYDFPEGIGRKKCFLMYHEELESLVR
NLPGIRRARFWMTFSDNYLNHLKVLENVGMTRIDPVRYNGQDIVPLQFLKELLPDPASLGPRTKGKTCIGNVMHGVKDGK
EKSLYVYNVCDHEECYREVGSQAISYTTGVPAMIGAMMMVTGKWQGSGVFNMEQLDPDPFMEELNKRGLPWKEVILKG
>Mature_397_residues
AKVLILGAGGVGSVAAHKCAQAPEIFSEIVLASRTVSKCVAIADSIRQRTGRTIETAQVDADNVAEMVQLINAVKPDLVV
NLALPYQDLPVMDACLETGVNYLDTANYEPPDTARFEYKWQWEYQDRFREKGLMALLGSGFDPGVTNVFAAHAVKHHFDE
IHVLDIIDCNAGDHGYPFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMQYDFPEGIGRKKCFLMYHEELESLVRN
LPGIRRARFWMTFSDNYLNHLKVLENVGMTRIDPVRYNGQDIVPLQFLKELLPDPASLGPRTKGKTCIGNVMHGVKDGKE
KSLYVYNVCDHEECYREVGSQAISYTTGVPAMIGAMMMVTGKWQGSGVFNMEQLDPDPFMEELNKRGLPWKEVILKG

Specific function: Unknown

COG id: COG1748

COG function: function code E; Saccharopine dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.7

Molecular weight: Translated: 44819; Mature: 44688

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLILGAGGVGSVAAHKCAQAPEIFSEIVLASRTVSKCVAIADSIRQRTGRTIETAQV
CCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
DADNVAEMVQLINAVKPDLVVNLALPYQDLPVMDACLETGVNYLDTANYEPPDTARFEYK
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCEEEEE
WQWEYQDRFREKGLMALLGSGFDPGVTNVFAAHAVKHHFDEIHVLDIIDCNAGDHGYPFA
EEECHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCC
TNFNPEINIREVTARGRYWERGEWVETDPLSWSMQYDFPEGIGRKKCFLMYHEELESLVR
CCCCCCCEEEEEEECCCCCCCCCCEECCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHH
NLPGIRRARFWMTFSDNYLNHLKVLENVGMTRIDPVRYNGQDIVPLQFLKELLPDPASLG
HCCCCEEEEEEEEECHHHHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHCCCCCCCC
PRTKGKTCIGNVMHGVKDGKEKSLYVYNVCDHEECYREVGSQAISYTTGVPAMIGAMMMV
CCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TGKWQGSGVFNMEQLDPDPFMEELNKRGLPWKEVILKG
CCCCCCCCCEEHHHCCCCHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
AKVLILGAGGVGSVAAHKCAQAPEIFSEIVLASRTVSKCVAIADSIRQRTGRTIETAQV
CEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
DADNVAEMVQLINAVKPDLVVNLALPYQDLPVMDACLETGVNYLDTANYEPPDTARFEYK
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCEEEEE
WQWEYQDRFREKGLMALLGSGFDPGVTNVFAAHAVKHHFDEIHVLDIIDCNAGDHGYPFA
EEECHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCC
TNFNPEINIREVTARGRYWERGEWVETDPLSWSMQYDFPEGIGRKKCFLMYHEELESLVR
CCCCCCCEEEEEEECCCCCCCCCCEECCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHH
NLPGIRRARFWMTFSDNYLNHLKVLENVGMTRIDPVRYNGQDIVPLQFLKELLPDPASLG
HCCCCEEEEEEEEECHHHHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHCCCCCCCC
PRTKGKTCIGNVMHGVKDGKEKSLYVYNVCDHEECYREVGSQAISYTTGVPAMIGAMMMV
CCCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TGKWQGSGVFNMEQLDPDPFMEELNKRGLPWKEVILKG
CCCCCCCCCEEHHHCCCCHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N6-(L-1,3-dicarboxypropyl)-L-lysine; NAD+; H2O

Specific reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA