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The map label for this gene is glnM [H]

Identifier: 78355443

GI number: 78355443

Start: 389595

End: 390428

Strand: Direct

Name: glnM [H]

Synonym: Dde_0396

Alternate gene names: 78355443

Gene position: 389595-390428 (Clockwise)

Preceding gene: 78355442

Following gene: 78355444

Centisome position: 10.44

GC content: 58.63

Gene sequence:

>834_bases
ATGTCATCATCCCGTACTGCCGCAGGCCGCCGCGGGGGCCTGTTTGAACGCCTGCCTCTGTGGCTGCTGGCCGCCTTGTT
CATTGCCGTGCTGATATGCTGGAACATGGCCGCCGATGCAGACTATACCGCTATTTTCGTGACGGTCCGCAAAGGCGTGG
CCGTCACCCTTTATGTATCATTCATCGCATATGCGCTGTCTCTGCTGGCAGGGCTGGTGCTCGGGCTGTGGCGCGTTTCG
CGCTGCAGGCTGCTGCGCGAGGCGGCCACGTTTTATATTGAAATAGTGCGCGGCATCCCCATGCTGGTCATTCTGTACTA
CATTGCCTTTGTGGGGGCCCCCGGTCTGGTGGATGCACTCAACTGGCTGCTTTCGCCGCTGATTGAAGCCGGTCTGACCG
CCCGCATCAGTGTGCGCTCGCTGGATTTTACATGGCGGGCCATCCTGGCGCTTACGGTGGGGTATTCTGCATTTATTGCC
GAAATAGTGCGCGCAGGTGTTGAGTCTGTGGCCGCAGGGCAGATGGAAGCGGCGCGTTCTCTGGGACTGAGCCGCTGGCA
GGCCATGCGCAAGGTAGTTCTGCCGCAGGCGCTGCGCAATGTGCTGCCGCCTCTGGCTAATGACTTTGTGGCCATGCTCA
AGGATTCGGCTCTGGTTTCGGCTCTGGGCGTTCAGGATATCACGCAGCTGGGCAAGGTGTATTCCGCATCCACATTCATG
TTTTTTGAAACGTACAATGTTGTGGCTTTTTTGTATCTGGTGATGACCATAGGTCTTTCGCTGTGCATCAGGGGGCTGGA
ACGGCGGCGGGGGTGCGGGCCTGTAAGGTTGTAG

Upstream 100 bases:

>100_bases
ACGCTCTGAGCCGGCGGTGGTTTTACGAATACAGGTAACGCAACGTGCAGCGGCCGGTTCTGCCCGGGCAAAGCCGTTCC
GCTGTATCCGTAAGAGAACG

Downstream 100 bases:

>100_bases
ATGTGCAGACCCGCGGTGCGGCAATGCCCCCCGCGGTGCGGTGGCTGAGTGTGCAGACACCCGCACCGCGCGGCGGGCAG
TGGGACGGCAGGGCATATCC

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSSSRTAAGRRGGLFERLPLWLLAALFIAVLICWNMAADADYTAIFVTVRKGVAVTLYVSFIAYALSLLAGLVLGLWRVS
RCRLLREAATFYIEIVRGIPMLVILYYIAFVGAPGLVDALNWLLSPLIEAGLTARISVRSLDFTWRAILALTVGYSAFIA
EIVRAGVESVAAGQMEAARSLGLSRWQAMRKVVLPQALRNVLPPLANDFVAMLKDSALVSALGVQDITQLGKVYSASTFM
FFETYNVVAFLYLVMTIGLSLCIRGLERRRGCGPVRL

Sequences:

>Translated_277_residues
MSSSRTAAGRRGGLFERLPLWLLAALFIAVLICWNMAADADYTAIFVTVRKGVAVTLYVSFIAYALSLLAGLVLGLWRVS
RCRLLREAATFYIEIVRGIPMLVILYYIAFVGAPGLVDALNWLLSPLIEAGLTARISVRSLDFTWRAILALTVGYSAFIA
EIVRAGVESVAAGQMEAARSLGLSRWQAMRKVVLPQALRNVLPPLANDFVAMLKDSALVSALGVQDITQLGKVYSASTFM
FFETYNVVAFLYLVMTIGLSLCIRGLERRRGCGPVRL
>Mature_276_residues
SSSRTAAGRRGGLFERLPLWLLAALFIAVLICWNMAADADYTAIFVTVRKGVAVTLYVSFIAYALSLLAGLVLGLWRVSR
CRLLREAATFYIEIVRGIPMLVILYYIAFVGAPGLVDALNWLLSPLIEAGLTARISVRSLDFTWRAILALTVGYSAFIAE
IVRAGVESVAAGQMEAARSLGLSRWQAMRKVVLPQALRNVLPPLANDFVAMLKDSALVSALGVQDITQLGKVYSASTFMF
FETYNVVAFLYLVMTIGLSLCIRGLERRRGCGPVRL

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=232, Percent_Identity=34.4827586206897, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788226, Length=219, Percent_Identity=31.9634703196347, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082239, Length=251, Percent_Identity=30.6772908366534, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994930, Length=218, Percent_Identity=33.9449541284404, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786873, Length=219, Percent_Identity=26.9406392694064, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786874, Length=224, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788646, Length=226, Percent_Identity=30.5309734513274, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788645, Length=219, Percent_Identity=28.310502283105, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787087, Length=209, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30321; Mature: 30189

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSSRTAAGRRGGLFERLPLWLLAALFIAVLICWNMAADADYTAIFVTVRKGVAVTLYVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEHHCCHHHHHHHH
FIAYALSLLAGLVLGLWRVSRCRLLREAATFYIEIVRGIPMLVILYYIAFVGAPGLVDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NWLLSPLIEAGLTARISVRSLDFTWRAILALTVGYSAFIAEIVRAGVESVAAGQMEAARS
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLSRWQAMRKVVLPQALRNVLPPLANDFVAMLKDSALVSALGVQDITQLGKVYSASTFM
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFETYNVVAFLYLVMTIGLSLCIRGLERRRGCGPVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]