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The map label for this gene is trpB [H]

Identifier: 78355126

GI number: 78355126

Start: 68277

End: 69425

Strand: Direct

Name: trpB [H]

Synonym: Dde_0079

Alternate gene names: 78355126

Gene position: 68277-69425 (Clockwise)

Preceding gene: 78355124

Following gene: 78355128

Centisome position: 1.83

GC content: 59.01

Gene sequence:

>1149_bases
GTGCCGGATTCGCTCAAACCCATTCTGGACGAGCTTGCCGCCACGTTTGAACGGTACAGAAACGACCCCGGGTTTCTGGA
GGAATTCAACTACTACCTTACCCGCTACTCGGGCCGCGAGACACCGCTGTATCTTTGTGCCAATCTGACACGGCGCCTCG
GCGGGGCCAAAATATATCTCAAGCGCGAGGATCTGAACCATCTGGGTGCCCATAAGGTCAACAACACCATCGGGCAGATT
CTGCTGGCCAAGCGCATGGGCAAAAAGAAAATCATCGCCGAAACAGGTGCCGGACAGCATGGCGTGGCCACTGCGGCGAC
AGCCGCGCTGATGGGCATGGAGTGCACCATATATATGGGGGCGGAAGACGTGGAGCGTCAGAAGCTCAATGTGTTCCGCA
TGCAGATGATGGGAGCCCGAGTGGTTCCCGCAACAAGCGGCCAGCAGACTCTTAAGGAAGCCGTCGACGAAGCTCTTGCC
GCCTGGATACGCGAAGCCGATACAACGTTCTATCTGCTGGGTTCGGCCGTGGGGCCGCATCCCTTCCCGCTTATGGTACG
AGAATTCCAGTCCGTCATAGGGCGTGAGCTGCGGGCCCAGATGCTGGAAGCCGAAGGCCGTCTGCCGGATTACTGCATCG
CCTGCGTGGGCGGCGGTTCCAATGCCATCGGCATGTTTTCCGGTTTCATCAATGATGACGGCGTGCGTCTTGTGGGGGTG
GAACCGGCGGGCCGCGGGCTTGAATACGGTGACCACGCCGCCACGCTGTGCTTAGGTGAACCGGGTGTCATGCATGGCTT
TAATTCATATATGCTGAAGGATCAGGCAGGAGAGCCTGCGGCCGTGTACTCCATTTCCGCCGGGCTGGACTATCCCGGAG
TGGGACCCGAGCACAGCCACCTTAAAGATCTGGGCCGTGCGGAATATGTAAATGCCAGCGATGCGGAGGCCCTCAGCGCA
TTTTTCGATCTGTCGCGTACAGAAGGCATCATACCTGCGCTGGAGTCAGCCCACGCACTGGCATACGCCATGCGTCTTGC
GCCGACCCTGTCTTCCGACAAGATCATAGCAGTGAACCTGTCGGGCCGCGGCGACAAGGACGTGGCACAGGTGGAACGTA
TGGTCAGAGAGGGGCTTGTGACGCCATAA

Upstream 100 bases:

>100_bases
TCTGCCGGCAACAAGCCTTTTGCTTTCACTCAGGAGTATACCATGACCAGCGTTCCCTCTGCTGACGGATTTTTCGGCGC
TTACGGCGGCCAGTAAGTAT

Downstream 100 bases:

>100_bases
GGCTTTTCGGCCCGGCTTTTGTGAAAGTGTAAAGGAAGAGGCGGCCTTTTGCCGCCTCTTTTTACGTAATAAAATCGGAT
TGTTGTCAGAAAAGTAGAAA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MPDSLKPILDELAATFERYRNDPGFLEEFNYYLTRYSGRETPLYLCANLTRRLGGAKIYLKREDLNHLGAHKVNNTIGQI
LLAKRMGKKKIIAETGAGQHGVATAATAALMGMECTIYMGAEDVERQKLNVFRMQMMGARVVPATSGQQTLKEAVDEALA
AWIREADTTFYLLGSAVGPHPFPLMVREFQSVIGRELRAQMLEAEGRLPDYCIACVGGGSNAIGMFSGFINDDGVRLVGV
EPAGRGLEYGDHAATLCLGEPGVMHGFNSYMLKDQAGEPAAVYSISAGLDYPGVGPEHSHLKDLGRAEYVNASDAEALSA
FFDLSRTEGIIPALESAHALAYAMRLAPTLSSDKIIAVNLSGRGDKDVAQVERMVREGLVTP

Sequences:

>Translated_382_residues
MPDSLKPILDELAATFERYRNDPGFLEEFNYYLTRYSGRETPLYLCANLTRRLGGAKIYLKREDLNHLGAHKVNNTIGQI
LLAKRMGKKKIIAETGAGQHGVATAATAALMGMECTIYMGAEDVERQKLNVFRMQMMGARVVPATSGQQTLKEAVDEALA
AWIREADTTFYLLGSAVGPHPFPLMVREFQSVIGRELRAQMLEAEGRLPDYCIACVGGGSNAIGMFSGFINDDGVRLVGV
EPAGRGLEYGDHAATLCLGEPGVMHGFNSYMLKDQAGEPAAVYSISAGLDYPGVGPEHSHLKDLGRAEYVNASDAEALSA
FFDLSRTEGIIPALESAHALAYAMRLAPTLSSDKIIAVNLSGRGDKDVAQVERMVREGLVTP
>Mature_381_residues
PDSLKPILDELAATFERYRNDPGFLEEFNYYLTRYSGRETPLYLCANLTRRLGGAKIYLKREDLNHLGAHKVNNTIGQIL
LAKRMGKKKIIAETGAGQHGVATAATAALMGMECTIYMGAEDVERQKLNVFRMQMMGARVVPATSGQQTLKEAVDEALAA
WIREADTTFYLLGSAVGPHPFPLMVREFQSVIGRELRAQMLEAEGRLPDYCIACVGGGSNAIGMFSGFINDDGVRLVGVE
PAGRGLEYGDHAATLCLGEPGVMHGFNSYMLKDQAGEPAAVYSISAGLDYPGVGPEHSHLKDLGRAEYVNASDAEALSAF
FDLSRTEGIIPALESAHALAYAMRLAPTLSSDKIIAVNLSGRGDKDVAQVERMVREGLVTP

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=377, Percent_Identity=54.3766578249337, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321412, Length=376, Percent_Identity=52.3936170212766, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 41351; Mature: 41220

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSLKPILDELAATFERYRNDPGFLEEFNYYLTRYSGRETPLYLCANLTRRLGGAKIYL
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEE
KREDLNHLGAHKVNNTIGQILLAKRMGKKKIIAETGAGQHGVATAATAALMGMECTIYMG
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCEEEEEEC
AEDVERQKLNVFRMQMMGARVVPATSGQQTLKEAVDEALAAWIREADTTFYLLGSAVGPH
CHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
PFPLMVREFQSVIGRELRAQMLEAEGRLPDYCIACVGGGSNAIGMFSGFINDDGVRLVGV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCCEEEEEE
EPAGRGLEYGDHAATLCLGEPGVMHGFNSYMLKDQAGEPAAVYSISAGLDYPGVGPEHSH
CCCCCCCCCCCCCEEEEECCCCHHHCCHHHHEECCCCCCEEEEEEECCCCCCCCCCCHHH
LKDLGRAEYVNASDAEALSAFFDLSRTEGIIPALESAHALAYAMRLAPTLSSDKIIAVNL
HHHCCHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
SGRGDKDVAQVERMVREGLVTP
CCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PDSLKPILDELAATFERYRNDPGFLEEFNYYLTRYSGRETPLYLCANLTRRLGGAKIYL
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEE
KREDLNHLGAHKVNNTIGQILLAKRMGKKKIIAETGAGQHGVATAATAALMGMECTIYMG
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCEEEEEEC
AEDVERQKLNVFRMQMMGARVVPATSGQQTLKEAVDEALAAWIREADTTFYLLGSAVGPH
CHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
PFPLMVREFQSVIGRELRAQMLEAEGRLPDYCIACVGGGSNAIGMFSGFINDDGVRLVGV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCCEEEEEE
EPAGRGLEYGDHAATLCLGEPGVMHGFNSYMLKDQAGEPAAVYSISAGLDYPGVGPEHSH
CCCCCCCCCCCCCEEEEECCCCHHHCCHHHHEECCCCCCEEEEEEECCCCCCCCCCCHHH
LKDLGRAEYVNASDAEALSAFFDLSRTEGIIPALESAHALAYAMRLAPTLSSDKIIAVNL
HHHCCHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
SGRGDKDVAQVERMVREGLVTP
CCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA