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The map label for this gene is ilvE [H]

Identifier: 78355112

GI number: 78355112

Start: 55979

End: 56902

Strand: Direct

Name: ilvE [H]

Synonym: Dde_0065

Alternate gene names: 78355112

Gene position: 55979-56902 (Clockwise)

Preceding gene: 161485612

Following gene: 78355113

Centisome position: 1.5

GC content: 56.93

Gene sequence:

>924_bases
ATGGTCCAGAAATCGGAAACGATCTGGTTTGACGGCAAGCAGGTTGCATGGGACGATGCCAATGTGCACGTTTTGACCCA
CACCCTGCATTACGGTCTGGGCGTGTTCGAGGGAATCCGCGCCTATAAGTGTGTTGACGGCACTTCCGCCGTGTTCCGCC
TGCGCGAACATGTCGAACGCCTGTTTGCTTCGGCCCGCATTCTGCGCATGGAAATTCCCTATACCGTCGACCAGCTTGTG
GATGCCGTGGTGGAAACGCTGCAGCGCAACAAACTGGACGAAGGCTATATCCGCCCCTTGAGCTTTGTGGGCGCGGGTGC
CATGGGTGTGAACCCCGGCAGCAACCCCATACAGACCATCATTGCCACGTGGCCCTGGGGCGCGTATCTGGGTGAAGAGG
CGCTGGAAGCGGGCATCCGCGTAAAAACCAGTTCCTTCCAGCGTCATCATGTAAACGCCATGATGACCAAGGCAAAGGCC
GTGGGCAACTATGTAAACTCCATTCTGGCCAAAACAGAAGCTCTTGCAGACGGTTACGACGAAGGGCTGATGCTGGATAC
CGCGGGATTTGTTTCTGAAGCCACCGGCGAAAACATTTTCATCGTGCGCGGCGGCGTCATTAAAACAACGCCCCTTACGT
CCATACTGGACGGTATCACCCGCAACAGCCTGATGACGCTGGCCGGTGATCTGGGCTACACCGTGGTGGAACAGCAGTTC
ACCCGCGATGAGCTGTATGTGGCCGATGAAGCCTTTTTCTGCGGCACTGCGGCGGAGGTCACTCCCATACGTGAAGTGGA
CCGCCGCGTTATCGGCGCCGGCAAGGCCGGACCGGTCACCAAGCATCTGCAGACCGAGTACTTCAAGCTTGTAAAGGGTG
AAAATCCCAAGTACGCACACTGGCTGCATCAGTATTCACTGTAG

Upstream 100 bases:

>100_bases
TTAGCGTGCGTTGTTGGCTTGAGTGCAATCATTCTCGTCGCTCCGCATGGGAGTCCGACGCAACCCGCGTCTGCGCAAGG
GCGCGTAAAGGGGTTTACTA

Downstream 100 bases:

>100_bases
CGGCATACGCCTTTCCGGCCGGCCCTGCCTCGGCAGGGCCGGTTTTTCACCCTTTTAGCCCCCCCACTTATGAGTCACGC
ATCGCTAACCGCAAAATACA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MVQKSETIWFDGKQVAWDDANVHVLTHTLHYGLGVFEGIRAYKCVDGTSAVFRLREHVERLFASARILRMEIPYTVDQLV
DAVVETLQRNKLDEGYIRPLSFVGAGAMGVNPGSNPIQTIIATWPWGAYLGEEALEAGIRVKTSSFQRHHVNAMMTKAKA
VGNYVNSILAKTEALADGYDEGLMLDTAGFVSEATGENIFIVRGGVIKTTPLTSILDGITRNSLMTLAGDLGYTVVEQQF
TRDELYVADEAFFCGTAAEVTPIREVDRRVIGAGKAGPVTKHLQTEYFKLVKGENPKYAHWLHQYSL

Sequences:

>Translated_307_residues
MVQKSETIWFDGKQVAWDDANVHVLTHTLHYGLGVFEGIRAYKCVDGTSAVFRLREHVERLFASARILRMEIPYTVDQLV
DAVVETLQRNKLDEGYIRPLSFVGAGAMGVNPGSNPIQTIIATWPWGAYLGEEALEAGIRVKTSSFQRHHVNAMMTKAKA
VGNYVNSILAKTEALADGYDEGLMLDTAGFVSEATGENIFIVRGGVIKTTPLTSILDGITRNSLMTLAGDLGYTVVEQQF
TRDELYVADEAFFCGTAAEVTPIREVDRRVIGAGKAGPVTKHLQTEYFKLVKGENPKYAHWLHQYSL
>Mature_307_residues
MVQKSETIWFDGKQVAWDDANVHVLTHTLHYGLGVFEGIRAYKCVDGTSAVFRLREHVERLFASARILRMEIPYTVDQLV
DAVVETLQRNKLDEGYIRPLSFVGAGAMGVNPGSNPIQTIIATWPWGAYLGEEALEAGIRVKTSSFQRHHVNAMMTKAKA
VGNYVNSILAKTEALADGYDEGLMLDTAGFVSEATGENIFIVRGGVIKTTPLTSILDGITRNSLMTLAGDLGYTVVEQQF
TRDELYVADEAFFCGTAAEVTPIREVDRRVIGAGKAGPVTKHLQTEYFKLVKGENPKYAHWLHQYSL

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=286, Percent_Identity=26.5734265734266, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI48994963, Length=304, Percent_Identity=49.3421052631579, Blast_Score=295, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17565728, Length=284, Percent_Identity=26.7605633802817, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322608, Length=288, Percent_Identity=26.7361111111111, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322002, Length=264, Percent_Identity=26.8939393939394, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33931; Mature: 33931

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQKSETIWFDGKQVAWDDANVHVLTHTLHYGLGVFEGIRAYKCVDGTSAVFRLREHVER
CCCCCCEEEECCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
LFASARILRMEIPYTVDQLVDAVVETLQRNKLDEGYIRPLSFVGAGAMGVNPGSNPIQTI
HHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHH
IATWPWGAYLGEEALEAGIRVKTSSFQRHHVNAMMTKAKAVGNYVNSILAKTEALADGYD
EEECCCHHHHCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGLMLDTAGFVSEATGENIFIVRGGVIKTTPLTSILDGITRNSLMTLAGDLGYTVVEQQF
CCEEEECCHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TRDELYVADEAFFCGTAAEVTPIREVDRRVIGAGKAGPVTKHLQTEYFKLVKGENPKYAH
CCCCEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
WLHQYSL
HHHHCCC
>Mature Secondary Structure
MVQKSETIWFDGKQVAWDDANVHVLTHTLHYGLGVFEGIRAYKCVDGTSAVFRLREHVER
CCCCCCEEEECCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
LFASARILRMEIPYTVDQLVDAVVETLQRNKLDEGYIRPLSFVGAGAMGVNPGSNPIQTI
HHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHH
IATWPWGAYLGEEALEAGIRVKTSSFQRHHVNAMMTKAKAVGNYVNSILAKTEALADGYD
EEECCCHHHHCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGLMLDTAGFVSEATGENIFIVRGGVIKTTPLTSILDGITRNSLMTLAGDLGYTVVEQQF
CCEEEECCHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TRDELYVADEAFFCGTAAEVTPIREVDRRVIGAGKAGPVTKHLQTEYFKLVKGENPKYAH
CCCCEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
WLHQYSL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]