Click here to switch to the map view.

The map label for this gene is engA

Identifier: 161485612

GI number: 161485612

Start: 51957

End: 53324

Strand: Direct

Name: engA

Synonym: Dde_0062

Alternate gene names: 161485612

Gene position: 51957-53324 (Clockwise)

Preceding gene: 78355108

Following gene: 78355112

Centisome position: 1.39

GC content: 58.55

Gene sequence:

>1368_bases
ATGTTACCCAAGATAGCTCTCATCGGTCGCCCCAACGTGGGCAAATCCACCCTTTTCAACAGGCTGATCCGCAGCAACAG
AGCCATAACCCATGACCGTCCCGGAGTAACCCGTGACCGCATGGAAGGCTATGTGAAAGTGGGAGACCGGAAGTTCATCA
TTATTGACACCGGCGGCATAACGCTGGACGAACACGCTGCCGTGGCGGAAGGGCCGGACGAACTGCGCGGGTTCGAGGCG
GAGATTCTGCGCCAGACGGAAGAGGCCATTGCCGATTCCGTGGCCTTGTGCCTGGTTGTGGACGGACGCGAGGGGCTGAC
TCCCTTTGACGAAAGTCTGGCCGCGTATGTGCGCAAATCGGGCAAGCCCGTGCTGCTGGCCGTCAACAAGGTGGACGGCG
AAGAAATGGCCGACCTGTACATGGCCGAATTCCATACGCTGGGCTTTCCGGTCATCCCGCTTTCCGGCGCTCACGGATTC
AATGTGCGGGCATTCAGCGGCGAGTTGTTTGACCTGCTGCCTCCCGAAGACGAAGACGCCCCGCAGGAAGAAGAGGAACG
CCCCCTCAAACTGGCCATGCTGGGCCGCCCCAATGCGGGCAAGTCTTCGCTGGTCAACGCCCTGAGCGGCAGCCGCCGCA
TGATTGTTTCCGATGTGGCGGGCACCACCCGCGACAGTGTGGATATTGCCGTGGAACTGGGCGGCAGGCGCTATGTTTTT
GTGGATACGGCCGGAGTGCGCCGTCGGGCAAAGATTCAGGACCCTGTGGAACGGTACAGCGTCAACTCTTCGCTCAAGTC
GACAACCAAGGCCGATGTGACGCTGGTGGTGCTGGATGCGGTGGAAGGTCTGACACAGCAGGACAAGCGGCTCATTGATC
TGCTGGACGAGCGCAAGACGCCGTTCATGCTGGTGATCAACAAAATTGACCTTGTGCCCCGGGATGGCCTGACCGCGCTG
AAGCGTCTGTACGATGATGCCCTGACATTCTGCAAGCATGTGCCCATCATGTACATTTCTGCGCGCAGCGGCCGCGGAGT
GGACAAGCTGCTGCCCATGGCCCGTAAAATTAACAAGGAATGTTATGTGCGCGTGGGTACGGGGCTGCTGAACCGGACAC
TTACGGAAGCAGTCACCCGCCACCAGCCGCCGGTGGTCAAACGGGTGCGTCCCAAATTCTTTTATCTGACGCAGGCGGAA
ACCAACCCGCCGACGTTTGTGTTTTTTGTCAACGACCATGAGCGTATTCAGGAGTCGTATGCGCGGTATCTGGAAAAATT
CATGCGGAAACGGTTTGAAATCGAGCATGCCCCCATGCGGGTGCGTTTCCGGTCGAGCCACACCAAAAACCGTGACAGAA
AAAAATAG

Upstream 100 bases:

>100_bases
GCCTTTGCAGGGGATTCCCGCCGCGGTCGCCCGCAATCACATGGCAGGCCTGCCGGTCTGCTGCATACGCGCAAGGCTCT
GCCTCGCACCGGAAAATATC

Downstream 100 bases:

>100_bases
GCACTCTGCCCTGCCCGTATACTGAACGGCGCCGGATTCCTGTGGAATCCGGCGCCGTTTTTGTCTGTCCGGTACATGAT
GCCGCCGTGCTGACGGCATG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLPKIALIGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGYVKVGDRKFIIIDTGGITLDEHAAVAEGPDELRGFEA
EILRQTEEAIADSVALCLVVDGREGLTPFDESLAAYVRKSGKPVLLAVNKVDGEEMADLYMAEFHTLGFPVIPLSGAHGF
NVRAFSGELFDLLPPEDEDAPQEEEERPLKLAMLGRPNAGKSSLVNALSGSRRMIVSDVAGTTRDSVDIAVELGGRRYVF
VDTAGVRRRAKIQDPVERYSVNSSLKSTTKADVTLVVLDAVEGLTQQDKRLIDLLDERKTPFMLVINKIDLVPRDGLTAL
KRLYDDALTFCKHVPIMYISARSGRGVDKLLPMARKINKECYVRVGTGLLNRTLTEAVTRHQPPVVKRVRPKFFYLTQAE
TNPPTFVFFVNDHERIQESYARYLEKFMRKRFEIEHAPMRVRFRSSHTKNRDRKK

Sequences:

>Translated_455_residues
MLPKIALIGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGYVKVGDRKFIIIDTGGITLDEHAAVAEGPDELRGFEA
EILRQTEEAIADSVALCLVVDGREGLTPFDESLAAYVRKSGKPVLLAVNKVDGEEMADLYMAEFHTLGFPVIPLSGAHGF
NVRAFSGELFDLLPPEDEDAPQEEEERPLKLAMLGRPNAGKSSLVNALSGSRRMIVSDVAGTTRDSVDIAVELGGRRYVF
VDTAGVRRRAKIQDPVERYSVNSSLKSTTKADVTLVVLDAVEGLTQQDKRLIDLLDERKTPFMLVINKIDLVPRDGLTAL
KRLYDDALTFCKHVPIMYISARSGRGVDKLLPMARKINKECYVRVGTGLLNRTLTEAVTRHQPPVVKRVRPKFFYLTQAE
TNPPTFVFFVNDHERIQESYARYLEKFMRKRFEIEHAPMRVRFRSSHTKNRDRKK
>Mature_455_residues
MLPKIALIGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGYVKVGDRKFIIIDTGGITLDEHAAVAEGPDELRGFEA
EILRQTEEAIADSVALCLVVDGREGLTPFDESLAAYVRKSGKPVLLAVNKVDGEEMADLYMAEFHTLGFPVIPLSGAHGF
NVRAFSGELFDLLPPEDEDAPQEEEERPLKLAMLGRPNAGKSSLVNALSGSRRMIVSDVAGTTRDSVDIAVELGGRRYVF
VDTAGVRRRAKIQDPVERYSVNSSLKSTTKADVTLVVLDAVEGLTQQDKRLIDLLDERKTPFMLVINKIDLVPRDGLTAL
KRLYDDALTFCKHVPIMYISARSGRGVDKLLPMARKINKECYVRVGTGLLNRTLTEAVTRHQPPVVKRVRPKFFYLTQAE
TNPPTFVFFVNDHERIQESYARYLEKFMRKRFEIEHAPMRVRFRSSHTKNRDRKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=472, Percent_Identity=37.7118644067797, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI1788919, Length=185, Percent_Identity=31.8918918918919, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367268, Length=168, Percent_Identity=33.9285714285714, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17507259, Length=185, Percent_Identity=31.3513513513514, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=169, Percent_Identity=31.3609467455621, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51205; Mature: 51205

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKIALIGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGYVKVGDRKFIIIDTGGI
CCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEEECCEEEEEEECCCE
TLDEHAAVAEGPDELRGFEAEILRQTEEAIADSVALCLVVDGREGLTPFDESLAAYVRKS
EECCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHCC
GKPVLLAVNKVDGEEMADLYMAEFHTLGFPVIPLSGAHGFNVRAFSGELFDLLPPEDEDA
CCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCEECCCCCCCCC
PQEEEERPLKLAMLGRPNAGKSSLVNALSGSRRMIVSDVAGTTRDSVDIAVELGGRRYVF
CCCHHCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCEEEEE
VDTAGVRRRAKIQDPVERYSVNSSLKSTTKADVTLVVLDAVEGLTQQDKRLIDLLDERKT
EECCCCCCHHHCCCHHHHHHCCCHHHCCCCCCEEEEEEEHHHCHHHHHHHHHHHHHCCCC
PFMLVINKIDLVPRDGLTALKRLYDDALTFCKHVPIMYISARSGRGVDKLLPMARKINKE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCC
CYVRVGTGLLNRTLTEAVTRHQPPVVKRVRPKFFYLTQAETNPPTFVFFVNDHERIQESY
EEEEECCHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCCCCEEEEEECCHHHHHHHH
ARYLEKFMRKRFEIEHAPMRVRFRSSHTKNRDRKK
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLPKIALIGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGYVKVGDRKFIIIDTGGI
CCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEEECCEEEEEEECCCE
TLDEHAAVAEGPDELRGFEAEILRQTEEAIADSVALCLVVDGREGLTPFDESLAAYVRKS
EECCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHCC
GKPVLLAVNKVDGEEMADLYMAEFHTLGFPVIPLSGAHGFNVRAFSGELFDLLPPEDEDA
CCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCEECCCCCCCCC
PQEEEERPLKLAMLGRPNAGKSSLVNALSGSRRMIVSDVAGTTRDSVDIAVELGGRRYVF
CCCHHCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCEEEEE
VDTAGVRRRAKIQDPVERYSVNSSLKSTTKADVTLVVLDAVEGLTQQDKRLIDLLDERKT
EECCCCCCHHHCCCHHHHHHCCCHHHCCCCCCEEEEEEEHHHCHHHHHHHHHHHHHCCCC
PFMLVINKIDLVPRDGLTALKRLYDDALTFCKHVPIMYISARSGRGVDKLLPMARKINKE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCC
CYVRVGTGLLNRTLTEAVTRHQPPVVKRVRPKFFYLTQAETNPPTFVFFVNDHERIQESY
EEEEECCHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCCCCEEEEEECCHHHHHHHH
ARYLEKFMRKRFEIEHAPMRVRFRSSHTKNRDRKK
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA