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The map label for this gene is cheW [H]

Identifier: 78223510

GI number: 78223510

Start: 2616202

End: 2616696

Strand: Reverse

Name: cheW [H]

Synonym: Gmet_2307

Alternate gene names: 78223510

Gene position: 2616696-2616202 (Counterclockwise)

Preceding gene: 78223511

Following gene: 78223509

Centisome position: 65.46

GC content: 57.17

Gene sequence:

>495_bases
ATGATGGAAACCGACATCCAGGAAATTCAGCTTGCCTGTTTCCGTCTGGGTGATGCGAATTTTGCCGCTGACATCATGAG
GATCAAGGAAATCCTCAAGCCTCAGCACCTGACGAAGCTACCCAGGACACCGTCCTTTGTGGAAGGGGTAATCAATCTTC
GCGGCACGGTCATTCCGGTTATGGATCTGCGCAAGCGGTTCGAGCTTCCTGAACGCGCTCCGCTGGAGGAATCACGGCTT
TTGGTGGTAACCGTGTCCCGCCAACTCGTGGGGCTCGTCGTGGACGACGTCACCGAGGTCGTTACGGTCCAAGCCCATGA
CATCAAGCCCCCTCCCCATGTGGCCGAGGGGATCAGCACCGAGTACCTGATCGGCGTCTGTCTTGTCCGCGACAGCCTCA
TCATGCTTCTCAATCTTGACACTATTCTGAACAGCCGTGAAACATCGGCTCTCGCCGGCTTCTCACGGGCATCGGGCGCA
ACTCCCGCCCGATAA

Upstream 100 bases:

>100_bases
CAAGTCGGCAAAGATCATTGAGATAATTCAGGATCTCCTCTCTCCTTAACGGGAGGGAGCCAGACAGAAACCATTTAAAT
GTGCTGCCCCAGGGGGGATG

Downstream 100 bases:

>100_bases
TTCCGGAAAAAGAGGATACCCGCAGTGTGTGCGGGAATCCTGACAGTTCGACAAGGAGACCGTCAGTGGGCGATCTTGAA
CACATACGTACTCAACTTAC

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MMETDIQEIQLACFRLGDANFAADIMRIKEILKPQHLTKLPRTPSFVEGVINLRGTVIPVMDLRKRFELPERAPLEESRL
LVVTVSRQLVGLVVDDVTEVVTVQAHDIKPPPHVAEGISTEYLIGVCLVRDSLIMLLNLDTILNSRETSALAGFSRASGA
TPAR

Sequences:

>Translated_164_residues
MMETDIQEIQLACFRLGDANFAADIMRIKEILKPQHLTKLPRTPSFVEGVINLRGTVIPVMDLRKRFELPERAPLEESRL
LVVTVSRQLVGLVVDDVTEVVTVQAHDIKPPPHVAEGISTEYLIGVCLVRDSLIMLLNLDTILNSRETSALAGFSRASGA
TPAR
>Mature_164_residues
MMETDIQEIQLACFRLGDANFAADIMRIKEILKPQHLTKLPRTPSFVEGVINLRGTVIPVMDLRKRFELPERAPLEESRL
LVVTVSRQLVGLVVDDVTEVVTVQAHDIKPPPHVAEGISTEYLIGVCLVRDSLIMLLNLDTILNSRETSALAGFSRASGA
TPAR

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=142, Percent_Identity=35.2112676056338, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18141; Mature: 18141

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50851 CHEW ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMETDIQEIQLACFRLGDANFAADIMRIKEILKPQHLTKLPRTPSFVEGVINLRGTVIPV
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHCCCCEEHH
MDLRKRFELPERAPLEESRLLVVTVSRQLVGLVVDDVTEVVTVQAHDIKPPPHVAEGIST
HHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEEEECCCCCCCHHHHCCCH
EYLIGVCLVRDSLIMLLNLDTILNSRETSALAGFSRASGATPAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHCCCCCCCC
>Mature Secondary Structure
MMETDIQEIQLACFRLGDANFAADIMRIKEILKPQHLTKLPRTPSFVEGVINLRGTVIPV
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHCCCCEEHH
MDLRKRFELPERAPLEESRLLVVTVSRQLVGLVVDDVTEVVTVQAHDIKPPPHVAEGIST
HHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEEEECCCCCCCHHHHCCCH
EYLIGVCLVRDSLIMLLNLDTILNSRETSALAGFSRASGATPAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]