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The map label for this gene is phoP [H]

Identifier: 78223511

GI number: 78223511

Start: 2616748

End: 2617119

Strand: Reverse

Name: phoP [H]

Synonym: Gmet_2308

Alternate gene names: 78223511

Gene position: 2617119-2616748 (Counterclockwise)

Preceding gene: 78223512

Following gene: 78223510

Centisome position: 65.47

GC content: 56.18

Gene sequence:

>372_bases
ATGACGAAGAAAAAAATTCTGATCGTCGAGGATGAGGAAAGCCTTCTCAAGCTTGAAAGCATTCTCCTCACGTCCAGGGG
GTATGAAGTGGTGGGTGCCACCGACGGGGTGGCCGCCCTTGAACAGGTCGGCTTGACCAGGCCCGATCTGGTCATCCTCG
ACATCATGCTTCCGGAGATAGATGGCTTTGAGGTCTGCCGGCGCATCAAGCAGAATCCCGAAACGGCACACACTCCCGTC
GTGATGCTTACGGCCAAGAAGAGCGAGCAGGACTGCGCGCGAGGGATGGCGGCGGGCGCGTCGGCCTACGTCACCAAACC
GTTCAAGTCGGCAAAGATCATTGAGATAATTCAGGATCTCCTCTCTCCTTAA

Upstream 100 bases:

>100_bases
ATGACGGAAAGATCGTCATTATGCTCGCAATGGAAAAGGTTCTTGACGTGTTGCTGCTCTGAAATCGTGCCCCATTTTAA
TGGCGCGAAAGGGTCCAGAC

Downstream 100 bases:

>100_bases
CGGGAGGGAGCCAGACAGAAACCATTTAAATGTGCTGCCCCAGGGGGGATGATGATGGAAACCGACATCCAGGAAATTCA
GCTTGCCTGTTTCCGTCTGG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MTKKKILIVEDEESLLKLESILLTSRGYEVVGATDGVAALEQVGLTRPDLVILDIMLPEIDGFEVCRRIKQNPETAHTPV
VMLTAKKSEQDCARGMAAGASAYVTKPFKSAKIIEIIQDLLSP

Sequences:

>Translated_123_residues
MTKKKILIVEDEESLLKLESILLTSRGYEVVGATDGVAALEQVGLTRPDLVILDIMLPEIDGFEVCRRIKQNPETAHTPV
VMLTAKKSEQDCARGMAAGASAYVTKPFKSAKIIEIIQDLLSP
>Mature_122_residues
TKKKILIVEDEESLLKLESILLTSRGYEVVGATDGVAALEQVGLTRPDLVILDIMLPEIDGFEVCRRIKQNPETAHTPVV
MLTAKKSEQDCARGMAAGASAYVTKPFKSAKIIEIIQDLLSP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=36.4406779661017, Blast_Score=88, Evalue=2e-19,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=36.7521367521368, Blast_Score=72, Evalue=7e-15,
Organism=Escherichia coli, GI1790860, Length=122, Percent_Identity=33.6065573770492, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.0508474576271, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=37.1900826446281, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=9e-14,
Organism=Escherichia coli, GI87082012, Length=110, Percent_Identity=33.6363636363636, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1787487, Length=124, Percent_Identity=33.8709677419355, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1786911, Length=104, Percent_Identity=35.5769230769231, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=32.2033898305085, Blast_Score=66, Evalue=8e-13,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=32.4786324786325, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1790863, Length=122, Percent_Identity=33.6065573770492, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=106, Percent_Identity=33.9622641509434, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI2367329, Length=118, Percent_Identity=37.2881355932203, Blast_Score=63, Evalue=7e-12,
Organism=Escherichia coli, GI1790552, Length=117, Percent_Identity=35.042735042735, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13425; Mature: 13294

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKKILIVEDEESLLKLESILLTSRGYEVVGATDGVAALEQVGLTRPDLVILDIMLPEI
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEECCCC
DGFEVCRRIKQNPETAHTPVVMLTAKKSEQDCARGMAAGASAYVTKPFKSAKIIEIIQDL
CHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
LSP
HCC
>Mature Secondary Structure 
TKKKILIVEDEESLLKLESILLTSRGYEVVGATDGVAALEQVGLTRPDLVILDIMLPEI
CCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEECCCC
DGFEVCRRIKQNPETAHTPVVMLTAKKSEQDCARGMAAGASAYVTKPFKSAKIIEIIQDL
CHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
LSP
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]