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The map label for this gene is surE

Identifier: 78222631

GI number: 78222631

Start: 1587092

End: 1587850

Strand: Direct

Name: surE

Synonym: Gmet_1419

Alternate gene names: 78222631

Gene position: 1587092-1587850 (Clockwise)

Preceding gene: 78222630

Following gene: 78222632

Centisome position: 39.7

GC content: 55.34

Gene sequence:

>759_bases
ATGAAAATTCTTGTTACGAATGACGACGGAGTTCGCGCTCCGGGGATACGGTCGCTTGCAGAGGCATTGCGGAACATCGG
TGATGTGGTTGTTGTTGCGCCCGACCGCGAACGGAGTGCCGTTGGGCACGCCTTGACACTGCACCATCCTTTACGGGCCT
CTGAGATACGCCCTGCGGTTTTTGCCGTGGATGGAACCCCTACAGATTGCGTTAACCTCGGCATCCATACGCTCCTCGGT
TCAAGACCCGATATAGTCGTATCGGGGGTCAACTGCGGTGGCAACATGGGAGATGATATCACCTATTCGGGGACGGTTTC
CGCTGCCATGGAAGCAACGCTCATGGGGATCCCCGCGCTGGCGGTCTCGCTCGCCACCTCTGGCCGCGGGGATAACTATG
CGGTTGCCTCCGCTTTCGCTGCCAGGCTTGTTCGGATTGTGTCCGAAAGGGGGCTCCCCCCGGATACCCTGTTAAATGTC
AATGTGCCAGACCTCCCCCTGGAAAAGCTCGGAGGAGCTGTTGTGACCATTCAAGGGAAAAGGGACTACGAGGGGAAAAT
TGTTACAAAAACTGATCCCCGCGGTCGCAACTATTATTGGATCGGGAATGGTTCATTGCAGTTCCGCGATCTGGAGGGTA
CCGATTATTACGCTGTGAAGCGCGGTTTGGTCTCGATAACGCCACTGCACCTCGACCTCACCAATTATGCTTCCCTCACC
ACGCTGAAAACATGGGATTTTGCAGAAATGACTTTGTGA

Upstream 100 bases:

>100_bases
TTCGAATCCAGTCGCCCCGACCATTTTCACCGTAGACGGTTTCGGACTCCGAAACCGTCTTTTTTTTTTCGGCTTTCCGG
GTGAACATTTTGAGGAAACT

Downstream 100 bases:

>100_bases
GGGATTGAGGCAATATGTCAACCGACGTTGCGCCCGGATGAGCCCTTGTCCTAACGCTGGACAGGACTGAGGTGGTCTGT
TATAGTCTGCATTTCAGCTA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKILVTNDDGVRAPGIRSLAEALRNIGDVVVVAPDRERSAVGHALTLHHPLRASEIRPAVFAVDGTPTDCVNLGIHTLLG
SRPDIVVSGVNCGGNMGDDITYSGTVSAAMEATLMGIPALAVSLATSGRGDNYAVASAFAARLVRIVSERGLPPDTLLNV
NVPDLPLEKLGGAVVTIQGKRDYEGKIVTKTDPRGRNYYWIGNGSLQFRDLEGTDYYAVKRGLVSITPLHLDLTNYASLT
TLKTWDFAEMTL

Sequences:

>Translated_252_residues
MKILVTNDDGVRAPGIRSLAEALRNIGDVVVVAPDRERSAVGHALTLHHPLRASEIRPAVFAVDGTPTDCVNLGIHTLLG
SRPDIVVSGVNCGGNMGDDITYSGTVSAAMEATLMGIPALAVSLATSGRGDNYAVASAFAARLVRIVSERGLPPDTLLNV
NVPDLPLEKLGGAVVTIQGKRDYEGKIVTKTDPRGRNYYWIGNGSLQFRDLEGTDYYAVKRGLVSITPLHLDLTNYASLT
TLKTWDFAEMTL
>Mature_252_residues
MKILVTNDDGVRAPGIRSLAEALRNIGDVVVVAPDRERSAVGHALTLHHPLRASEIRPAVFAVDGTPTDCVNLGIHTLLG
SRPDIVVSGVNCGGNMGDDITYSGTVSAAMEATLMGIPALAVSLATSGRGDNYAVASAFAARLVRIVSERGLPPDTLLNV
NVPDLPLEKLGGAVVTIQGKRDYEGKIVTKTDPRGRNYYWIGNGSLQFRDLEGTDYYAVKRGLVSITPLHLDLTNYASLT
TLKTWDFAEMTL

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=246, Percent_Identity=48.3739837398374, Blast_Score=220, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_GEOMG (Q39VS1)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384378.1
- ProteinModelPortal:   Q39VS1
- SMR:   Q39VS1
- STRING:   Q39VS1
- GeneID:   3738947
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1419
- NMPDR:   fig|269799.3.peg.1260
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   Q39VS1
- ProtClustDB:   PRK00346
- BioCyc:   GMET269799:GMET_1419-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 26884; Mature: 26884

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVTNDDGVRAPGIRSLAEALRNIGDVVVVAPDRERSAVGHALTLHHPLRASEIRPAV
CEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHCCEEEEECCCCCCCCCCEE
FAVDGTPTDCVNLGIHTLLGSRPDIVVSGVNCGGNMGDDITYSGTVSAAMEATLMGIPAL
EEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCHHH
AVSLATSGRGDNYAVASAFAARLVRIVSERGLPPDTLLNVNVPDLPLEKLGGAVVTIQGK
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCHHHHCCEEEEEECC
RDYEGKIVTKTDPRGRNYYWIGNGSLQFRDLEGTDYYAVKRGLVSITPLHLDLTNYASLT
CCCCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCEECCCCEEEEEEEEECCCCCEEE
TLKTWDFAEMTL
EEECCCCCCCCC
>Mature Secondary Structure
MKILVTNDDGVRAPGIRSLAEALRNIGDVVVVAPDRERSAVGHALTLHHPLRASEIRPAV
CEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHCCEEEEECCCCCCCCCCEE
FAVDGTPTDCVNLGIHTLLGSRPDIVVSGVNCGGNMGDDITYSGTVSAAMEATLMGIPAL
EEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCHHH
AVSLATSGRGDNYAVASAFAARLVRIVSERGLPPDTLLNVNVPDLPLEKLGGAVVTIQGK
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCHHHHCCEEEEEECC
RDYEGKIVTKTDPRGRNYYWIGNGSLQFRDLEGTDYYAVKRGLVSITPLHLDLTNYASLT
CCCCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCEECCCCEEEEEEEEECCCCCEEE
TLKTWDFAEMTL
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA