Click here to switch to the map view.

The map label for this gene is frr

Identifier: 78222467

GI number: 78222467

Start: 1413013

End: 1413570

Strand: Direct

Name: frr

Synonym: Gmet_1253

Alternate gene names: 78222467

Gene position: 1413013-1413570 (Clockwise)

Preceding gene: 78222466

Following gene: 78222468

Centisome position: 35.35

GC content: 53.58

Gene sequence:

>558_bases
ATGACGAAAGAAGTCATTGCCGACATGAAGGCGCACATGGAAAAGTCGGTTGACGCACTTCGCCGCGAATACCAGAAGGT
GCGCACCGGCAGGGCCACCACCGGGCTTCTCGATGATATCAAGGTTGAATACTACGGGAATCCTTCGCCCCTCAGTCAGG
TGGCGACCCTTTCTGTCCCCGAGCCCCGGACGATAACCATCCAACCTTGGGAGGCCAAGTTGATCCCGGTTATCGAAAAG
GCGATCATGAACGCGAATCTTGGTTTTACCCCGGCCAATGACGGTAAGACGATCCGCATTTCCCTTCCGCCTCTCACCGA
AGAGCGCCGGAAGGAAATCGTCAAAACACTCAAGAAAATGGCTGAGGATACCAAGGTTGCGGTTCGCAACATTCGCCGTG
ACGGGATTGATAGCCTCAAAAAGCTGGAGAAGGATAAGAAGATTTCCGAAGACGATCTGAAGCGCGCCGAGAAGGAAGTG
CAGGATGTCACGAACACGTTCGTGGCAAAGGTTGAGGAAGTGCTTACGCACAAGGAGAAAGAGGTTCTGGAGGTCTGA

Upstream 100 bases:

>100_bases
AACAATCTCCCCATTATCGTTTTTGACATCACCACATATGGCAACATAAAAAAGGTGGTGTGCGGTGAAGAGATCGGCAC
CGTTGTGAAAGGAGAATAGC

Downstream 100 bases:

>100_bases
TGCCGCGCTAAGCGGGAAAAAAGTATTTTTCCGCTTTTTGCTTGCGCACCAAGTGCTTTTATGCTTTAATCCCCTTTAAC
CCCTCAATTAAAGGGGATTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTKEVIADMKAHMEKSVDALRREYQKVRTGRATTGLLDDIKVEYYGNPSPLSQVATLSVPEPRTITIQPWEAKLIPVIEK
AIMNANLGFTPANDGKTIRISLPPLTEERRKEIVKTLKKMAEDTKVAVRNIRRDGIDSLKKLEKDKKISEDDLKRAEKEV
QDVTNTFVAKVEEVLTHKEKEVLEV

Sequences:

>Translated_185_residues
MTKEVIADMKAHMEKSVDALRREYQKVRTGRATTGLLDDIKVEYYGNPSPLSQVATLSVPEPRTITIQPWEAKLIPVIEK
AIMNANLGFTPANDGKTIRISLPPLTEERRKEIVKTLKKMAEDTKVAVRNIRRDGIDSLKKLEKDKKISEDDLKRAEKEV
QDVTNTFVAKVEEVLTHKEKEVLEV
>Mature_184_residues
TKEVIADMKAHMEKSVDALRREYQKVRTGRATTGLLDDIKVEYYGNPSPLSQVATLSVPEPRTITIQPWEAKLIPVIEKA
IMNANLGFTPANDGKTIRISLPPLTEERRKEIVKTLKKMAEDTKVAVRNIRRDGIDSLKKLEKDKKISEDDLKRAEKEVQ
DVTNTFVAKVEEVLTHKEKEVLEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=172, Percent_Identity=28.4883720930233, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=45.6521739130435, Blast_Score=175, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=9e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_GEOMG (Q39W85)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384214.1
- ProteinModelPortal:   Q39W85
- SMR:   Q39W85
- STRING:   Q39W85
- GeneID:   3738796
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1253
- NMPDR:   fig|269799.3.peg.1931
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q39W85
- ProtClustDB:   PRK00083
- BioCyc:   GMET269799:GMET_1253-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21022; Mature: 20890

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEVIADMKAHMEKSVDALRREYQKVRTGRATTGLLDDIKVEYYGNPSPLSQVATLSVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHCEEEECCCCCCHHHHHCCCCC
EPRTITIQPWEAKLIPVIEKAIMNANLGFTPANDGKTIRISLPPLTEERRKEIVKTLKKM
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
AEDTKVAVRNIRRDGIDSLKKLEKDKKISEDDLKRAEKEVQDVTNTFVAKVEEVLTHKEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVLEV
HHHCC
>Mature Secondary Structure 
TKEVIADMKAHMEKSVDALRREYQKVRTGRATTGLLDDIKVEYYGNPSPLSQVATLSVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHCEEEECCCCCCHHHHHCCCCC
EPRTITIQPWEAKLIPVIEKAIMNANLGFTPANDGKTIRISLPPLTEERRKEIVKTLKKM
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
AEDTKVAVRNIRRDGIDSLKKLEKDKKISEDDLKRAEKEVQDVTNTFVAKVEEVLTHKEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVLEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA