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The map label for this gene is sucC

Identifier: 78188316

GI number: 78188316

Start: 379999

End: 381171

Strand: Reverse

Name: sucC

Synonym: Cag_0338

Alternate gene names: 78188316

Gene position: 381171-379999 (Counterclockwise)

Preceding gene: 78188317

Following gene: 78188312

Centisome position: 14.82

GC content: 44.42

Gene sequence:

>1173_bases
ATGAACATTCATGAATATCAAGGCAAGGATATCCTCAGAAAATTTGGGGTTACCGTGCCAAAAGGCATTGTGGCTTATTC
GGCTGATGAAGCAAAGCAAGCAGCAGAGCAACTTTTTGCTGAAACGGGTTCTTCCGTTGTGGTTGTAAAAGCACAAATCC
ACGCAGGTGGACGGGGTAAAGCGGGTGGTGTTAAACTTGCAAAATCACCTGAAGAGGCATTTGAAATTGCTCGCCAAATG
ATTGGCATGACGCTTATTACGCATCAAACCGGTCCTGAAGGTAAAGTGGTAAGTCGGCTGCTTATTGAAGAGGGCATGGG
AATTGAAAAAGAATTTTACGTTGGCATCACGCTTGATCGTGCTACCTCACGCAATGTGTTGATGGTATCAACGGAAGGTG
GTATGGAAATTGAAACCGTTGCCGAAGAAACACCTGAAAAGCTCCTAAAAATTCAAATTGACCCGCTTTTCGGCATGCAA
GGCTTTCAAGCTCGCGAAGCCGCATTTTTCCTTGGGCTTGAGGGTGAACAGTTCCGCAATGCCGTAAATTTTATTACAGC
TCTTTATAAAGCTTACACCTCAATTGATGCCTCAGTGGCTGAAATTAATCCTTTAGTGGTTACTTCTGAAGGCAAGGTGA
TTGCTTTGGACGCAAAGATTAATTTTGATGATAACGCCCTCTATCGCCATAAAGAGTACATGGAATTGCGCGACACCAGC
GAGGAAGATCCATTTGAAGTTGAAGCTTCAAAGTCTAACTTGAACTATGTGCGCCTTGATGGTAATGTGGGCTGCATGGT
GAATGGCGCTGGCTTAGCAATGGGCACGATGGATATTATTCAGCTTGCTGGTGGTAAACCTGCAAACTTTCTTGATGTTG
GTGGCACAGCAAGTCCTCAAACCGTAGAAGAAGGCTTTAAGATTATTTTAAGCGATAAAAATGTTCGTGCTATTTTAGTG
AACATTTTTGGAGGCATTGTACGCTGCGACCGTGTAGCTGGAGGTATTATGGAAGCTGCCAAGAAAATGGATTTACACTT
GCCCGTTATTGTGCGCCTTGAGGGCACAAATGCGTCCATTGCACAGCAAATGCTTGATGAATCGGGCTTAAGCTTAATTG
CGGCTAAGGGGTTGCGTGATGCAGCTCAAAAGGTGCAAGAAGCATTAGCTTAA

Upstream 100 bases:

>100_bases
GCATTTGCTGTTTTAGCGTTACCCGTTTTAAAACCCAGATGTTTCGTAAAAATTTTTAGTGGCGCATGTATTTGTTTGTA
ACCCTAAGATTATCACCTGT

Downstream 100 bases:

>100_bases
CATTCATTAAACAAGTAAGAGACGAAAAATTCTCTACACTCTTTACTCCCCTCTTCTCTTTATGGATTAGAGGGGATTTT
TTATTCGTAGCGCAACGCCT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNIHEYQGKDILRKFGVTVPKGIVAYSADEAKQAAEQLFAETGSSVVVVKAQIHAGGRGKAGGVKLAKSPEEAFEIARQM
IGMTLITHQTGPEGKVVSRLLIEEGMGIEKEFYVGITLDRATSRNVLMVSTEGGMEIETVAEETPEKLLKIQIDPLFGMQ
GFQAREAAFFLGLEGEQFRNAVNFITALYKAYTSIDASVAEINPLVVTSEGKVIALDAKINFDDNALYRHKEYMELRDTS
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDIIQLAGGKPANFLDVGGTASPQTVEEGFKIILSDKNVRAILV
NIFGGIVRCDRVAGGIMEAAKKMDLHLPVIVRLEGTNASIAQQMLDESGLSLIAAKGLRDAAQKVQEALA

Sequences:

>Translated_390_residues
MNIHEYQGKDILRKFGVTVPKGIVAYSADEAKQAAEQLFAETGSSVVVVKAQIHAGGRGKAGGVKLAKSPEEAFEIARQM
IGMTLITHQTGPEGKVVSRLLIEEGMGIEKEFYVGITLDRATSRNVLMVSTEGGMEIETVAEETPEKLLKIQIDPLFGMQ
GFQAREAAFFLGLEGEQFRNAVNFITALYKAYTSIDASVAEINPLVVTSEGKVIALDAKINFDDNALYRHKEYMELRDTS
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDIIQLAGGKPANFLDVGGTASPQTVEEGFKIILSDKNVRAILV
NIFGGIVRCDRVAGGIMEAAKKMDLHLPVIVRLEGTNASIAQQMLDESGLSLIAAKGLRDAAQKVQEALA
>Mature_390_residues
MNIHEYQGKDILRKFGVTVPKGIVAYSADEAKQAAEQLFAETGSSVVVVKAQIHAGGRGKAGGVKLAKSPEEAFEIARQM
IGMTLITHQTGPEGKVVSRLLIEEGMGIEKEFYVGITLDRATSRNVLMVSTEGGMEIETVAEETPEKLLKIQIDPLFGMQ
GFQAREAAFFLGLEGEQFRNAVNFITALYKAYTSIDASVAEINPLVVTSEGKVIALDAKINFDDNALYRHKEYMELRDTS
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDIIQLAGGKPANFLDVGGTASPQTVEEGFKIILSDKNVRAILV
NIFGGIVRCDRVAGGIMEAAKKMDLHLPVIVRLEGTNASIAQQMLDESGLSLIAAKGLRDAAQKVQEALA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=47.4489795918367, Blast_Score=352, Evalue=2e-97,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=46.5116279069767, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=46.831955922865, Blast_Score=316, Evalue=2e-86,
Organism=Escherichia coli, GI1786948, Length=389, Percent_Identity=51.1568123393316, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=44.7236180904523, Blast_Score=335, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=42.7109974424552, Blast_Score=311, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=43.0730478589421, Blast_Score=335, Evalue=9e-93,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=45.088161209068, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=43.7017994858612, Blast_Score=315, Evalue=3e-86,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=43.7017994858612, Blast_Score=315, Evalue=3e-86,
Organism=Drosophila melanogaster, GI281361397, Length=390, Percent_Identity=43.8461538461538, Blast_Score=313, Evalue=9e-86,
Organism=Drosophila melanogaster, GI281361395, Length=390, Percent_Identity=43.8461538461538, Blast_Score=313, Evalue=9e-86,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_CHLCH (Q3ATR4)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378654.1
- HSSP:   P53590
- ProteinModelPortal:   Q3ATR4
- SMR:   Q3ATR4
- STRING:   Q3ATR4
- GeneID:   3748058
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0338
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- BioCyc:   CCHL340177:CAG_0338-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42016; Mature: 42016

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKDILRKFGVTVPKGIVAYSADEAKQAAEQLFAETGSSVVVVKAQIHAGGRGK
CCCCCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
AGGVKLAKSPEEAFEIARQMIGMTLITHQTGPEGKVVSRLLIEEGMGIEKEFYVGITLDR
CCCEEECCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEC
ATSRNVLMVSTEGGMEIETVAEETPEKLLKIQIDPLFGMQGFQAREAAFFLGLEGEQFRN
CCCCCEEEEECCCCCEEHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AVNFITALYKAYTSIDASVAEINPLVVTSEGKVIALDAKINFDDNALYRHKEYMELRDTS
HHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHCCC
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDIIQLAGGKPANFLDVGGTASPQ
CCCCEEEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCCH
TVEEGFKIILSDKNVRAILVNIFGGIVRCDRVAGGIMEAAKKMDLHLPVIVRLEGTNASI
HHHCCCEEEEECCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
AQQMLDESGLSLIAAKGLRDAAQKVQEALA
HHHHHHHCCCEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKDILRKFGVTVPKGIVAYSADEAKQAAEQLFAETGSSVVVVKAQIHAGGRGK
CCCCCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
AGGVKLAKSPEEAFEIARQMIGMTLITHQTGPEGKVVSRLLIEEGMGIEKEFYVGITLDR
CCCEEECCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEC
ATSRNVLMVSTEGGMEIETVAEETPEKLLKIQIDPLFGMQGFQAREAAFFLGLEGEQFRN
CCCCCEEEEECCCCCEEHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AVNFITALYKAYTSIDASVAEINPLVVTSEGKVIALDAKINFDDNALYRHKEYMELRDTS
HHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHCCC
EEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMGTMDIIQLAGGKPANFLDVGGTASPQ
CCCCEEEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCCCH
TVEEGFKIILSDKNVRAILVNIFGGIVRCDRVAGGIMEAAKKMDLHLPVIVRLEGTNASI
HHHCCCEEEEECCCCEEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
AQQMLDESGLSLIAAKGLRDAAQKVQEALA
HHHHHHHCCCEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA