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The map label for this gene is slyD [C]

Identifier: 78188227

GI number: 78188227

Start: 277904

End: 278332

Strand: Reverse

Name: slyD [C]

Synonym: Cag_0246

Alternate gene names: 78188227

Gene position: 278332-277904 (Counterclockwise)

Preceding gene: 78188228

Following gene: 78188224

Centisome position: 10.82

GC content: 45.69

Gene sequence:

>429_bases
ATGGCAACAGTAAAACAAGGGGATACCGTAAAAGTTCACTATGCAGGTAAACTTGATGATGGCACCCTTTTTGATACCTC
AGCAGGGCGCGAGCCACTGCAATTTACCGTTGGAGGTGGGCAGGTTATCCCTGGTTTTGATAACGCCATGATTGAAATGG
CGATTGGCGATAAAAAAGAGGTTGTGATTGCGGTTGAAGAAGCTTACGGACCTCATAGCGATGAGTTAGTAACAGCGGTG
CCTCGTGAGCGCTTTCCCGCTGATTTAGAGCTTGAAATTGGGCAGCAGTTGCAAGTTGGATTAGAAAATGGACAGCAGGC
AATTGTTATGGTGGTTGACATTACCGATGAAGCTGTAACGCTGGATGCCAACCATCCCTTAGCAGGGCAAGAACTAACCT
TTGAAATTGAGTTAGTAGAAATTGTGTAA

Upstream 100 bases:

>100_bases
GAAATAGAACGTGGACGATCACCACAAAACAGATGATTTTACATTAATAAGGTGGCTTACCATCAAACAAAAGTAAAGCT
GCCACTAACAAGGAGAAGAC

Downstream 100 bases:

>100_bases
CCCATTATTTGGTTTACGTTAAATTGAAAACGGCAGAGGAACAGAAGAGGTTGCTCTGCCGTTTGTGGTTTTAATGCACT
GAGCAGGAAATGCAAGGATC

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MATVKQGDTVKVHYAGKLDDGTLFDTSAGREPLQFTVGGGQVIPGFDNAMIEMAIGDKKEVVIAVEEAYGPHSDELVTAV
PRERFPADLELEIGQQLQVGLENGQQAIVMVVDITDEAVTLDANHPLAGQELTFEIELVEIV

Sequences:

>Translated_142_residues
MATVKQGDTVKVHYAGKLDDGTLFDTSAGREPLQFTVGGGQVIPGFDNAMIEMAIGDKKEVVIAVEEAYGPHSDELVTAV
PRERFPADLELEIGQQLQVGLENGQQAIVMVVDITDEAVTLDANHPLAGQELTFEIELVEIV
>Mature_141_residues
ATVKQGDTVKVHYAGKLDDGTLFDTSAGREPLQFTVGGGQVIPGFDNAMIEMAIGDKKEVVIAVEEAYGPHSDELVTAVP
RERFPADLELEIGQQLQVGLENGQQAIVMVVDITDEAVTLDANHPLAGQELTFEIELVEIV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706131, Length=64, Percent_Identity=43.75, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI219842220, Length=64, Percent_Identity=43.75, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI206725530, Length=67, Percent_Identity=44.7761194029851, Blast_Score=66, Evalue=8e-12,
Organism=Homo sapiens, GI17149844, Length=67, Percent_Identity=44.7761194029851, Blast_Score=66, Evalue=8e-12,
Organism=Homo sapiens, GI17149842, Length=67, Percent_Identity=44.7761194029851, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1789748, Length=132, Percent_Identity=34.0909090909091, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1786211, Length=140, Percent_Identity=30.7142857142857, Blast_Score=74, Evalue=3e-15,
Organism=Escherichia coli, GI87082390, Length=64, Percent_Identity=53.125, Blast_Score=64, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24655568, Length=88, Percent_Identity=38.6363636363636, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15275; Mature: 15144

Theoretical pI: Translated: 3.90; Mature: 3.90

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVKQGDTVKVHYAGKLDDGTLFDTSAGREPLQFTVGGGQVIPGFDNAMIEMAIGDKKE
CCCCCCCCEEEEEECCCCCCCEEEECCCCCCCEEEEECCCEEECCCCCEEEEEEECCCCE
VVIAVEEAYGPHSDELVTAVPRERFPADLELEIGQQLQVGLENGQQAIVMVVDITDEAVT
EEEEEECCCCCCCCCEEEECCCHHCCCCEEEECCCEEEEECCCCCEEEEEEEEECCCEEE
LDANHPLAGQELTFEIELVEIV
EECCCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure 
ATVKQGDTVKVHYAGKLDDGTLFDTSAGREPLQFTVGGGQVIPGFDNAMIEMAIGDKKE
CCCCCCCEEEEEECCCCCCCEEEECCCCCCCEEEEECCCEEECCCCCEEEEEEECCCCE
VVIAVEEAYGPHSDELVTAVPRERFPADLELEIGQQLQVGLENGQQAIVMVVDITDEAVT
EEEEEECCCCCCCCCEEEECCCHHCCCCEEEECCCEEEEECCCCCEEEEEEEEECCCEEE
LDANHPLAGQELTFEIELVEIV
EECCCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]