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The map label for this gene is glnH [H]

Identifier: 78188224

GI number: 78188224

Start: 274576

End: 275634

Strand: Reverse

Name: glnH [H]

Synonym: Cag_0243

Alternate gene names: 78188224

Gene position: 275634-274576 (Counterclockwise)

Preceding gene: 78188227

Following gene: 78188220

Centisome position: 10.72

GC content: 44.29

Gene sequence:

>1059_bases
ATGCGACTCTTATCCCTTTTCTTTTTGGCATTCTTCTTCTCTTTGCAGTCTATCGCCGCTGAAAATGAGCTGATAGTGGC
AACAAAACACTCTCCACCATTTGCCATGAAAAATGCTGAAGGAGAGTGGGAAGGCATTTCCATAGATTTGATGCACGCTC
TTGCCGAAAAGGGAAAAAGCAAGCTAACCTTCAAAGAAATGTCGCTTACGGAAATGCTCAAAGCTGTGGAACAGGGTGAG
GTTGATGCCGCTGCTGCTGCCATCACCATAACCAAAGAACGTGAATACCTGCTTGATTTTTCTGCCCCCTATTTTCACTC
TGGGCTAGCAATTGCAGTTAAAGAAAAGGAGACTCGCTGGTTTCACATGATCGGTCGCCTCTTCTCACCAGCCTTTTTAC
AAGTACTCGCCGCCCTTTCGCTCCTACTACTTATTTCAGGATTTTTGGTCTGGCTGTTCGAGCGTAAAAAAAATTCTGAC
CATTTCGGTGGAACTCCAGCTCAGGGAATTTGGTCAGGTTTTTGGTGGGCAGCCGTTACCATGACCACTGTTGGTTACGG
TGATAAAACACCAATAACGTTACTTGGAAAACTTGTTGCATTAGTTTGGATGTTCACCAGCTTGATGGTGATTTCAGGCT
TCACAGCGGCAATGACAACCGTTCTTACCGTTGAGAGTCTCGAAAGCGAGATCAAAGAATTCAACGATTTATATGGCAAA
AGAGTTGGAACGGTAAAGGCATCAAGCAGCAGCAGTTACCTTGAAGAGAGCACCATGAAAAGCAAGCACTTTCTTACCAT
TCAGGATGCACTTCATGCTCTCGAAAATGATCAGATTGATGCCGTTGTGTTCGATGAGCCAATTATGCGTTATGTACTCA
CCTTGGGCGACATTCATGGAGTTACAATCATCAATCAAGTGCTTAGCCCCGAATATTATGCAATTGCGCTACCGCAGGGC
AGCCAATTACGAGAAACTTTCAACCGTAACCTACTCGACATCACGGTTTCTGAGCGGTGGAAAAAAATCAACAATAAGTA
TCTTAATACAAAGCAATAG

Upstream 100 bases:

>100_bases
CCGACAAATTTTATCTTTGTAAGGACTTTGATATAATCATATAAAATCACCCTCCTACCCGAACCTCTTTCAAGGCAATC
TCCTTAAAAGAGAGAAAAAT

Downstream 100 bases:

>100_bases
GAGTTAGCGGTATTAACCCTCCCTCATTTCCAGCTTTGGTGAATGATCATTAAGAAACTCTACCCCTTCGCTTAACCTCC
CTTCACGAGCGTAACTTTCG

Product: extracellular solute-binding protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: GlnBP [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRLLSLFFLAFFFSLQSIAAENELIVATKHSPPFAMKNAEGEWEGISIDLMHALAEKGKSKLTFKEMSLTEMLKAVEQGE
VDAAAAAITITKEREYLLDFSAPYFHSGLAIAVKEKETRWFHMIGRLFSPAFLQVLAALSLLLLISGFLVWLFERKKNSD
HFGGTPAQGIWSGFWWAAVTMTTVGYGDKTPITLLGKLVALVWMFTSLMVISGFTAAMTTVLTVESLESEIKEFNDLYGK
RVGTVKASSSSSYLEESTMKSKHFLTIQDALHALENDQIDAVVFDEPIMRYVLTLGDIHGVTIINQVLSPEYYAIALPQG
SQLRETFNRNLLDITVSERWKKINNKYLNTKQ

Sequences:

>Translated_352_residues
MRLLSLFFLAFFFSLQSIAAENELIVATKHSPPFAMKNAEGEWEGISIDLMHALAEKGKSKLTFKEMSLTEMLKAVEQGE
VDAAAAAITITKEREYLLDFSAPYFHSGLAIAVKEKETRWFHMIGRLFSPAFLQVLAALSLLLLISGFLVWLFERKKNSD
HFGGTPAQGIWSGFWWAAVTMTTVGYGDKTPITLLGKLVALVWMFTSLMVISGFTAAMTTVLTVESLESEIKEFNDLYGK
RVGTVKASSSSSYLEESTMKSKHFLTIQDALHALENDQIDAVVFDEPIMRYVLTLGDIHGVTIINQVLSPEYYAIALPQG
SQLRETFNRNLLDITVSERWKKINNKYLNTKQ
>Mature_352_residues
MRLLSLFFLAFFFSLQSIAAENELIVATKHSPPFAMKNAEGEWEGISIDLMHALAEKGKSKLTFKEMSLTEMLKAVEQGE
VDAAAAAITITKEREYLLDFSAPYFHSGLAIAVKEKETRWFHMIGRLFSPAFLQVLAALSLLLLISGFLVWLFERKKNSD
HFGGTPAQGIWSGFWWAAVTMTTVGYGDKTPITLLGKLVALVWMFTSLMVISGFTAAMTTVLTVESLESEIKEFNDLYGK
RVGTVKASSSSSYLEESTMKSKHFLTIQDALHALENDQIDAVVFDEPIMRYVLTLGDIHGVTIINQVLSPEYYAIALPQG
SQLRETFNRNLLDITVSERWKKINNKYLNTKQ

Specific function: Involved in a glutamine-transport system glnHPQ [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Homo sapiens, GI55770852, Length=357, Percent_Identity=25.7703081232493, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI134304848, Length=377, Percent_Identity=24.4031830238727, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI163659858, Length=386, Percent_Identity=24.6113989637306, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI74275354, Length=377, Percent_Identity=24.4031830238727, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI167001419, Length=305, Percent_Identity=24.9180327868852, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI134304851, Length=377, Percent_Identity=24.4031830238727, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI163659856, Length=386, Percent_Identity=24.6113989637306, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI167001484, Length=305, Percent_Identity=24.5901639344262, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI223278356, Length=313, Percent_Identity=23.6421725239617, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI164419734, Length=379, Percent_Identity=23.2189973614776, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI164419736, Length=379, Percent_Identity=23.2189973614776, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI62988346, Length=314, Percent_Identity=25.4777070063694, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI55770854, Length=317, Percent_Identity=23.6593059936909, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI28416444, Length=273, Percent_Identity=24.5421245421245, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4504117, Length=273, Percent_Identity=24.5421245421245, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787031, Length=112, Percent_Identity=37.5, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71988861, Length=359, Percent_Identity=22.8412256267409, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193209667, Length=296, Percent_Identity=24.3243243243243, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25147803, Length=366, Percent_Identity=24.0437158469945, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25144707, Length=286, Percent_Identity=23.4265734265734, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71989779, Length=356, Percent_Identity=21.0674157303371, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71980671, Length=263, Percent_Identity=22.8136882129278, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71980669, Length=263, Percent_Identity=22.8136882129278, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221472680, Length=408, Percent_Identity=22.0588235294118, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI62484334, Length=360, Percent_Identity=24.7222222222222, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648478, Length=358, Percent_Identity=24.8603351955307, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640783, Length=377, Percent_Identity=23.342175066313, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648559, Length=272, Percent_Identity=24.2647058823529, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 1440 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 460 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR005768
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 39476; Mature: 39476

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLSLFFLAFFFSLQSIAAENELIVATKHSPPFAMKNAEGEWEGISIDLMHALAEKGKS
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
KLTFKEMSLTEMLKAVEQGEVDAAAAAITITKEREYLLDFSAPYFHSGLAIAVKEKETRW
CCCHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCHHEEECCCCHHHCCCEEEEECCHHHH
FHMIGRLFSPAFLQVLAALSLLLLISGFLVWLFERKKNSDHFGGTPAQGIWSGFWWAAVT
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
MTTVGYGDKTPITLLGKLVALVWMFTSLMVISGFTAAMTTVLTVESLESEIKEFNDLYGK
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RVGTVKASSSSSYLEESTMKSKHFLTIQDALHALENDQIDAVVFDEPIMRYVLTLGDIHG
CCCEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCH
VTIINQVLSPEYYAIALPQGSQLRETFNRNLLDITVSERWKKINNKYLNTKQ
HHHHHHHHCCCEEEEECCCCHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLLSLFFLAFFFSLQSIAAENELIVATKHSPPFAMKNAEGEWEGISIDLMHALAEKGKS
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
KLTFKEMSLTEMLKAVEQGEVDAAAAAITITKEREYLLDFSAPYFHSGLAIAVKEKETRW
CCCHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCHHEEECCCCHHHCCCEEEEECCHHHH
FHMIGRLFSPAFLQVLAALSLLLLISGFLVWLFERKKNSDHFGGTPAQGIWSGFWWAAVT
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
MTTVGYGDKTPITLLGKLVALVWMFTSLMVISGFTAAMTTVLTVESLESEIKEFNDLYGK
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RVGTVKASSSSSYLEESTMKSKHFLTIQDALHALENDQIDAVVFDEPIMRYVLTLGDIHG
CCCEEEECCCHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCH
VTIINQVLSPEYYAIALPQGSQLRETFNRNLLDITVSERWKKINNKYLNTKQ
HHHHHHHHCCCEEEEECCCCHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: Translocates substrate across the membrane [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]