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The map label for this gene is pqqL [C]

Identifier: 78188220

GI number: 78188220

Start: 269986

End: 271245

Strand: Reverse

Name: pqqL [C]

Synonym: Cag_0239

Alternate gene names: 78188220

Gene position: 271245-269986 (Counterclockwise)

Preceding gene: 78188224

Following gene: 78188219

Centisome position: 10.55

GC content: 48.33

Gene sequence:

>1260_bases
ATGGCACTCACCACATCAACCACCGTACACCTTGCAACGCTCCCCAACGGCATCACCGTTATTACCGATAGCGTCCCTTA
CGTTGAAAGTATTACGCTTGGCATTCAAATTAACGCGGGTTCACGCGACGACCCTGCTCATGCAGCAGGATTAGCGCACT
TTATGGAGCACGCCCTTTTTAAGGGAACGCGCACCCGTAGCTATCTTGATATTGCCCGTAGCGTTGAGCAACACGGTGGC
TATTTGGATGCCTATACCACGAAAGAGCAAACCTGCGTTTACCTCCGCTGCCTTGCCGCTCACTTAGAGCCATCGTTTGA
ACTGTTAGCCGATTTAGTATCAAACCCCACCTTTCCACCCGAAGAGATGGAAAAAGAGAAAGAGGTGGTGCTTGAAGAAA
TTAGCAGCATTAACGACACGCCAGAGGAGTTGATTTTTGAGGAATTTGACCAGCGCTCTTTTCCCAACCACCCTATTGGC
AACCCTATTTTGGGAACTGAAAAAAGTGTTGAAGCCTTTAGCCAAAACGACTTACACCTTTTTTTACAGCAGCATTACAT
TCCGCAAAAAATGGTGGTAACCGCTACAGGCAACGTATCGCACCATGCTATTATGCAACTCTGCGAACGCTTTTTAAACC
ACCTTGCAAATCCAGCAGAGAGCACCGAAACACGTCAGCCACTCTCGGTAGCAACCTACAAGCCATTTTCGCTTACCCTA
AAAAAGCGTATCTATCAAGCGCAAATTGTTATGGGCACCGCCATTGAGCGCAACGATCGCCACTTTTACAGCCTCATGGT
GCTCAACACCTTGCTTGGCAGCGGCATGAGCTCACTTTTAAATCTTGAATTGCGCGAAAAGCGAGGATTAGCCTATAACG
TTTACTCCTCCCTTGCTTTTTTTGACGATCTCACAGCGCTTAACATTTATGCGGGCACGGATGGCAACAAAGTGGCAACC
ACACTTACCTTAATAAAGGAATTGTTACAGAGCGATGCGCTGCACCATCCCATCCACGAAGAGTTACAAGCCGCAAAAAC
CAAGCTCCTTGGCTCACACATTATGGGTATGGAAAAAATGACGCGCCGCATGTCGAACACCGCCTCCGACTATGTTTATT
TTCGCCGCCACATTTCGCCCGACGAAAAAAGTGCCGCTATTGAAGCTGTTACCGCCTCCGACGTTACCGAAGCTGCTGAA
TTGCTCCTACGGCAGGCAACCTATTCAACCTTAGTGTATAAACCCTCACGGCAAGGCTAA

Upstream 100 bases:

>100_bases
AGTGATAATGAAAAGATACTTGCCGTTCTTAGCAAGAAGCGGCTAAAATAAGAATTAAACCGTACATTGCTTTCTATTAT
AATGAAACAAACAGGTTTCC

Downstream 100 bases:

>100_bases
ACGCACGTAACTTGAATTATTCATGAGCAACTTGCTCTCATCATGGTTCAGACATCTGGATTCCCGCCTTCGCGGGAATG
ACAAATGGACAAAAGAATCA

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MALTTSTTVHLATLPNGITVITDSVPYVESITLGIQINAGSRDDPAHAAGLAHFMEHALFKGTRTRSYLDIARSVEQHGG
YLDAYTTKEQTCVYLRCLAAHLEPSFELLADLVSNPTFPPEEMEKEKEVVLEEISSINDTPEELIFEEFDQRSFPNHPIG
NPILGTEKSVEAFSQNDLHLFLQQHYIPQKMVVTATGNVSHHAIMQLCERFLNHLANPAESTETRQPLSVATYKPFSLTL
KKRIYQAQIVMGTAIERNDRHFYSLMVLNTLLGSGMSSLLNLELREKRGLAYNVYSSLAFFDDLTALNIYAGTDGNKVAT
TLTLIKELLQSDALHHPIHEELQAAKTKLLGSHIMGMEKMTRRMSNTASDYVYFRRHISPDEKSAAIEAVTASDVTEAAE
LLLRQATYSTLVYKPSRQG

Sequences:

>Translated_419_residues
MALTTSTTVHLATLPNGITVITDSVPYVESITLGIQINAGSRDDPAHAAGLAHFMEHALFKGTRTRSYLDIARSVEQHGG
YLDAYTTKEQTCVYLRCLAAHLEPSFELLADLVSNPTFPPEEMEKEKEVVLEEISSINDTPEELIFEEFDQRSFPNHPIG
NPILGTEKSVEAFSQNDLHLFLQQHYIPQKMVVTATGNVSHHAIMQLCERFLNHLANPAESTETRQPLSVATYKPFSLTL
KKRIYQAQIVMGTAIERNDRHFYSLMVLNTLLGSGMSSLLNLELREKRGLAYNVYSSLAFFDDLTALNIYAGTDGNKVAT
TLTLIKELLQSDALHHPIHEELQAAKTKLLGSHIMGMEKMTRRMSNTASDYVYFRRHISPDEKSAAIEAVTASDVTEAAE
LLLRQATYSTLVYKPSRQG
>Mature_418_residues
ALTTSTTVHLATLPNGITVITDSVPYVESITLGIQINAGSRDDPAHAAGLAHFMEHALFKGTRTRSYLDIARSVEQHGGY
LDAYTTKEQTCVYLRCLAAHLEPSFELLADLVSNPTFPPEEMEKEKEVVLEEISSINDTPEELIFEEFDQRSFPNHPIGN
PILGTEKSVEAFSQNDLHLFLQQHYIPQKMVVTATGNVSHHAIMQLCERFLNHLANPAESTETRQPLSVATYKPFSLTLK
KRIYQAQIVMGTAIERNDRHFYSLMVLNTLLGSGMSSLLNLELREKRGLAYNVYSSLAFFDDLTALNIYAGTDGNKVATT
LTLIKELLQSDALHHPIHEELQAAKTKLLGSHIMGMEKMTRRMSNTASDYVYFRRHISPDEKSAAIEAVTASDVTEAAEL
LLRQATYSTLVYKPSRQG

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=401, Percent_Identity=26.6832917705736, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI46593007, Length=208, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI24308013, Length=422, Percent_Identity=25.8293838862559, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI50592988, Length=399, Percent_Identity=22.0551378446115, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=293, Percent_Identity=31.3993174061433, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17553678, Length=417, Percent_Identity=24.220623501199, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17510601, Length=428, Percent_Identity=23.1308411214953, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17569737, Length=280, Percent_Identity=26.7857142857143, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=424, Percent_Identity=24.7641509433962, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321813, Length=413, Percent_Identity=21.3075060532688, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357875, Length=403, Percent_Identity=28.287841191067, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24646943, Length=403, Percent_Identity=28.287841191067, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19921772, Length=433, Percent_Identity=22.8637413394919, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24667786, Length=339, Percent_Identity=24.7787610619469, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46760; Mature: 46628

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTTSTTVHLATLPNGITVITDSVPYVESITLGIQINAGSRDDPAHAAGLAHFMEHALF
CCEECCCEEEEEECCCCCEEEECCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
KGTRTRSYLDIARSVEQHGGYLDAYTTKEQTCVYLRCLAAHLEPSFELLADLVSNPTFPP
CCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCH
EEMEKEKEVVLEEISSINDTPEELIFEEFDQRSFPNHPIGNPILGTEKSVEAFSQNDLHL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCHHH
FLQQHYIPQKMVVTATGNVSHHAIMQLCERFLNHLANPAESTETRQPLSVATYKPFSLTL
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHH
KKRIYQAQIVMGTAIERNDRHFYSLMVLNTLLGSGMSSLLNLELREKRGLAYNVYSSLAF
HHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEHHHHHHHH
FDDLTALNIYAGTDGNKVATTLTLIKELLQSDALHHPIHEELQAAKTKLLGSHIMGMEKM
HHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRRMSNTASDYVYFRRHISPDEKSAAIEAVTASDVTEAAELLLRQATYSTLVYKPSRQG
HHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
ALTTSTTVHLATLPNGITVITDSVPYVESITLGIQINAGSRDDPAHAAGLAHFMEHALF
CEECCCEEEEEECCCCCEEEECCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
KGTRTRSYLDIARSVEQHGGYLDAYTTKEQTCVYLRCLAAHLEPSFELLADLVSNPTFPP
CCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCH
EEMEKEKEVVLEEISSINDTPEELIFEEFDQRSFPNHPIGNPILGTEKSVEAFSQNDLHL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCHHH
FLQQHYIPQKMVVTATGNVSHHAIMQLCERFLNHLANPAESTETRQPLSVATYKPFSLTL
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHH
KKRIYQAQIVMGTAIERNDRHFYSLMVLNTLLGSGMSSLLNLELREKRGLAYNVYSSLAF
HHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEHHHHHHHH
FDDLTALNIYAGTDGNKVATTLTLIKELLQSDALHHPIHEELQAAKTKLLGSHIMGMEKM
HHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRRMSNTASDYVYFRRHISPDEKSAAIEAVTASDVTEAAELLLRQATYSTLVYKPSRQG
HHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]