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The map label for this gene is ipk

Identifier: 78067600

GI number: 78067600

Start: 3275219

End: 3276100

Strand: Direct

Name: ipk

Synonym: Bcep18194_A6131

Alternate gene names: 78067600

Gene position: 3275219-3276100 (Clockwise)

Preceding gene: 78067599

Following gene: 78067601

Centisome position: 88.66

GC content: 59.75

Gene sequence:

>882_bases
ATGACCGATTCGACCCGCTCGCTGCGCAACTGCCTTGCGCCCGCGAAACTCAACCTGTTCCTGCACATCACCGGCCGCCG
TCCGAACGGCTATCACGACCTGCAGAGCGTGTTCCAGTTGCTGAACTGGGGCGACACGCTGCACTTCACGCTGCGCGACG
ACGGTCGCGTTGCACGCGTCACCGACGTGCCCGGCGTGCCCGAGGAAAGCGATCTCGTCGTGCGCGCGGCCAACCTGTTG
AAAGCGCATACGGGCACCGCGCACGGTGTCGACATCGAGATCGACAAGTGCCTGCCGATGGGAGCCGGCCTCGGCGGCGG
CAGCTCCGACGCGGCCACGACGCTGCTCGCGCTGAACCGCCTGTGGCAACTCGACCTGCCGCGCGCCGAACTCCAGTCGC
TCGCGGTAAAACTCGGTGCAGACGTCCCGTTTTTTATTTTTGGAAAAAATGCGTTCGCAGAGGGTATCGGAGAAGAATTA
GCTGAGGTACAATTGCCGACTCGCTGGTTCTTGGTTGTAACGCCCCGCGTTCACGTCCCAACCGCTGAAATATTTTCAGA
TGAGTTGTTGACAAGAGATTCGAAGCGCGTCACAATTACGGACTTTCTTGCACAGCAAAACAGCGACGCGGGATGGCCAG
ATAGTTTCGGTCGGAACGATATGCAGCAAGTTGTGACAAGTAAGTACGCGGAAGTTGCGCAGGTGGTCAAATGGTTGTAT
GATGTGACCCCCGCGAGGATGACCGGCTCCGGAGCAAGCGTGTTTGCAGCGTTTCGCAGCAAGCATGAGGCAGAAGCGGC
GCAAGCCAAGCTGCCCACCGGTTGGAACGGTGCAGTTGCCGAGAGCCTGAACGAGCATCCGCTCTTCGCTTTCGCGTCAT
GA

Upstream 100 bases:

>100_bases
GCCACGGGCGTCAAACGCGTCAACCTCGTGCGTGCGACACCGCCGCTCGACATCAAGCTAGTGCTCGATCAGTGAGCACC
CGCCTAGCCCAGACCTACGC

Downstream 100 bases:

>100_bases
AGTTTTACTTTGCCGAACGGCCTACACAAGTTCGGTGAAGTTATCAGTTAAGTGTAGGGGAGTCGCCAAGTTGGTCAAGG
CACCGGATTTTGATTCCGGC

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARVTDVPGVPEESDLVVRAANLL
KAHTGTAHGVDIEIDKCLPMGAGLGGGSSDAATTLLALNRLWQLDLPRAELQSLAVKLGADVPFFIFGKNAFAEGIGEEL
AEVQLPTRWFLVVTPRVHVPTAEIFSDELLTRDSKRVTITDFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLY
DVTPARMTGSGASVFAAFRSKHEAEAAQAKLPTGWNGAVAESLNEHPLFAFAS

Sequences:

>Translated_293_residues
MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARVTDVPGVPEESDLVVRAANLL
KAHTGTAHGVDIEIDKCLPMGAGLGGGSSDAATTLLALNRLWQLDLPRAELQSLAVKLGADVPFFIFGKNAFAEGIGEEL
AEVQLPTRWFLVVTPRVHVPTAEIFSDELLTRDSKRVTITDFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLY
DVTPARMTGSGASVFAAFRSKHEAEAAQAKLPTGWNGAVAESLNEHPLFAFAS
>Mature_292_residues
TDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARVTDVPGVPEESDLVVRAANLLK
AHTGTAHGVDIEIDKCLPMGAGLGGGSSDAATTLLALNRLWQLDLPRAELQSLAVKLGADVPFFIFGKNAFAEGIGEELA
EVQLPTRWFLVVTPRVHVPTAEIFSDELLTRDSKRVTITDFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLYD
VTPARMTGSGASVFAAFRSKHEAEAAQAKLPTGWNGAVAESLNEHPLFAFAS

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=282, Percent_Identity=46.8085106382979, Blast_Score=225, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31938; Mature: 31807

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARV
CCCCHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
TDVPGVPEESDLVVRAANLLKAHTGTAHGVDIEIDKCLPMGAGLGGGSSDAATTLLALNR
ECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LWQLDLPRAELQSLAVKLGADVPFFIFGKNAFAEGIGEELAEVQLPTRWFLVVTPRVHVP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCEECC
TAEIFSDELLTRDSKRVTITDFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLY
HHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DVTPARMTGSGASVFAAFRSKHEAEAAQAKLPTGWNGAVAESLNEHPLFAFAS
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEECC
>Mature Secondary Structure 
TDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARV
CCCHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
TDVPGVPEESDLVVRAANLLKAHTGTAHGVDIEIDKCLPMGAGLGGGSSDAATTLLALNR
ECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LWQLDLPRAELQSLAVKLGADVPFFIFGKNAFAEGIGEELAEVQLPTRWFLVVTPRVHVP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCEECC
TAEIFSDELLTRDSKRVTITDFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLY
HHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DVTPARMTGSGASVFAAFRSKHEAEAAQAKLPTGWNGAVAESLNEHPLFAFAS
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA