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The map label for this gene is lolB

Identifier: 78067599

GI number: 78067599

Start: 3274573

End: 3275193

Strand: Direct

Name: lolB

Synonym: Bcep18194_A6130

Alternate gene names: 78067599

Gene position: 3274573-3275193 (Clockwise)

Preceding gene: 78067598

Following gene: 78067600

Centisome position: 88.64

GC content: 69.89

Gene sequence:

>621_bases
ATGCAGATGTTCCCGACGTTTTCCCTGTCCTTCCGCGCGCAGCGCACGCTGGCCGCAGCCGGCGCGGCGCTCGCGCTCGC
CGGCTGCGCGAGCACGCCGCCGTCGGCCAGCGCGCCGACCGGCGCGGCGCTGCAGACCGCCGCAACCCACGCTTACCACG
GCCGCTTCGCGGTGCAGTACGACGACCGTCTCGGCAAGCAGCAGAACGTGTACGGCAACTTCGACTGGCAGGAGCACGGC
GACGACGTGTCGCTGGAGCTGCGCAGCCCGCTCGGCCAGACGCTCGCGGTCGTGAAATCGACGCCGCAGGCGGCATCGCT
CGAATTGCCGAACCGTCCGACGCAATATGCGCCGGACGTCGGCGACCTGATGCAGAAAACGCTCGGCTTCGAACTGCCGC
TCGCGGGCCTGCGCTACTGGCTACTGCCGACAGCCGCGCCCGCCACGCCCGCGGAGACGGTGCGCGATCCGGCCGACGGT
ACGCGCGTCAAGCAGATCCGCCAGGACGGCTGGACGATCGACTACCTTGCCTACGCGGATGCCCCGGCCACGGGCGTCAA
ACGCGTCAACCTCGTGCGTGCGACACCGCCGCTCGACATCAAGCTAGTGCTCGATCAGTGA

Upstream 100 bases:

>100_bases
AGGACGACGCGCGTTCCGCGTGGCGTGACGCGCAGAAGCTCGAGCCGGACAACGACACGCTCGTGCAGACGCTGAAACGC
CTCCAGATCAACGGTCTCTG

Downstream 100 bases:

>100_bases
GCACCCGCCTAGCCCAGACCTACGCATGACCGATTCGACCCGCTCGCTGCGCAACTGCCTTGCGCCCGCGAAACTCAACC
TGTTCCTGCACATCACCGGC

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MQMFPTFSLSFRAQRTLAAAGAALALAGCASTPPSASAPTGAALQTAATHAYHGRFAVQYDDRLGKQQNVYGNFDWQEHG
DDVSLELRSPLGQTLAVVKSTPQAASLELPNRPTQYAPDVGDLMQKTLGFELPLAGLRYWLLPTAAPATPAETVRDPADG
TRVKQIRQDGWTIDYLAYADAPATGVKRVNLVRATPPLDIKLVLDQ

Sequences:

>Translated_206_residues
MQMFPTFSLSFRAQRTLAAAGAALALAGCASTPPSASAPTGAALQTAATHAYHGRFAVQYDDRLGKQQNVYGNFDWQEHG
DDVSLELRSPLGQTLAVVKSTPQAASLELPNRPTQYAPDVGDLMQKTLGFELPLAGLRYWLLPTAAPATPAETVRDPADG
TRVKQIRQDGWTIDYLAYADAPATGVKRVNLVRATPPLDIKLVLDQ
>Mature_206_residues
MQMFPTFSLSFRAQRTLAAAGAALALAGCASTPPSASAPTGAALQTAATHAYHGRFAVQYDDRLGKQQNVYGNFDWQEHG
DDVSLELRSPLGQTLAVVKSTPQAASLELPNRPTQYAPDVGDLMQKTLGFELPLAGLRYWLLPTAAPATPAETVRDPADG
TRVKQIRQDGWTIDYLAYADAPATGVKRVNLVRATPPLDIKLVLDQ

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 22132; Mature: 22132

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMFPTFSLSFRAQRTLAAAGAALALAGCASTPPSASAPTGAALQTAATHAYHGRFAVQY
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEE
DDRLGKQQNVYGNFDWQEHGDDVSLELRSPLGQTLAVVKSTPQAASLELPNRPTQYAPDV
HHHCCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCH
GDLMQKTLGFELPLAGLRYWLLPTAAPATPAETVRDPADGTRVKQIRQDGWTIDYLAYAD
HHHHHHHCCCCCCHHHHHEEECCCCCCCCCHHHHCCCCCCHHHHHHHHCCCEEEEEEECC
APATGVKRVNLVRATPPLDIKLVLDQ
CCCCCCEEEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MQMFPTFSLSFRAQRTLAAAGAALALAGCASTPPSASAPTGAALQTAATHAYHGRFAVQY
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEE
DDRLGKQQNVYGNFDWQEHGDDVSLELRSPLGQTLAVVKSTPQAASLELPNRPTQYAPDV
HHHCCCCCCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCH
GDLMQKTLGFELPLAGLRYWLLPTAAPATPAETVRDPADGTRVKQIRQDGWTIDYLAYAD
HHHHHHHCCCCCCHHHHHEEECCCCCCCCCHHHHCCCCCCHHHHHHHHCCCEEEEEEECC
APATGVKRVNLVRATPPLDIKLVLDQ
CCCCCCEEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA