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The map label for this gene is rmlC [H]

Identifier: 78065445

GI number: 78065445

Start: 892398

End: 892949

Strand: Direct

Name: rmlC [H]

Synonym: Bcep18194_A3971

Alternate gene names: 78065445

Gene position: 892398-892949 (Clockwise)

Preceding gene: 78065444

Following gene: 78065446

Centisome position: 24.16

GC content: 60.87

Gene sequence:

>552_bases
ATGGCAATCCACGTAACGGCAACGGCACTGCCCGAAGTCAAGCTTATCGAGCCGAAGGTCTTTGGCGACGCGCGCGGGTA
TTTCTACGAGAGCTTCAACGCGCGCGAGTTTGCGGAGCACGTCGCTCCGGGTATCGAGTTCGTGCAGGACAATCACTCGC
GATCCGCAAAAGGCGTGCTGCGCGGGCTGCACTACCAGATCGAACACACGCAGGGCAAGCTGGTGCGCGTGGTTGAGGGC
GAGGTGTTCGACGTCGCAGTCGATGTGCGCCGCAGTTCGCCCAATTTCGGCAAGTGGGTCGGCGTGACGCTGTCCGCCGA
CAACCATCGGCAGCTTTGGGTTCCGCCGGGGTTCGCGCATGGCTTCCTTGTGGTGTCCGAGTCTGCTCAGTTTCTCTACA
AGACGACCGATTATTGGTTTCCCGAGCACGAGCGCAGCATTGTCTGGAACGATCCGGACATCGGAATCGTGTGGCCGCTG
GATGGCGAGCCGCTGCTGGCCGTCAAGGATGCCGCGGGCATGCGGTTGATGGACGCTGATCTTTTTGAGTGA

Upstream 100 bases:

>100_bases
GCAACTGGATCGACGCGGAGCAGGTGCTGAAACTGGCACAGCCGCTCGCGAAGAACGCCTACGGGCTGTATCTCCGGAAC
CTACTCACCCATCAGGTCGC

Downstream 100 bases:

>100_bases
GGTCGTGATGAATTCCGAGTCGACGATCCTCGTAACCGGTGTCACGGGTCAGGTAGGCTTTGAACTGCTGCGCTCGCTGC
AGGGGCTCGGCCGTGTGGTG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MAIHVTATALPEVKLIEPKVFGDARGYFYESFNAREFAEHVAPGIEFVQDNHSRSAKGVLRGLHYQIEHTQGKLVRVVEG
EVFDVAVDVRRSSPNFGKWVGVTLSADNHRQLWVPPGFAHGFLVVSESAQFLYKTTDYWFPEHERSIVWNDPDIGIVWPL
DGEPLLAVKDAAGMRLMDADLFE

Sequences:

>Translated_183_residues
MAIHVTATALPEVKLIEPKVFGDARGYFYESFNAREFAEHVAPGIEFVQDNHSRSAKGVLRGLHYQIEHTQGKLVRVVEG
EVFDVAVDVRRSSPNFGKWVGVTLSADNHRQLWVPPGFAHGFLVVSESAQFLYKTTDYWFPEHERSIVWNDPDIGIVWPL
DGEPLLAVKDAAGMRLMDADLFE
>Mature_182_residues
AIHVTATALPEVKLIEPKVFGDARGYFYESFNAREFAEHVAPGIEFVQDNHSRSAKGVLRGLHYQIEHTQGKLVRVVEGE
VFDVAVDVRRSSPNFGKWVGVTLSADNHRQLWVPPGFAHGFLVVSESAQFLYKTTDYWFPEHERSIVWNDPDIGIVWPLD
GEPLLAVKDAAGMRLMDADLFE

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=169, Percent_Identity=56.8047337278106, Blast_Score=197, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17550412, Length=163, Percent_Identity=47.8527607361963, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20637; Mature: 20505

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHVTATALPEVKLIEPKVFGDARGYFYESFNAREFAEHVAPGIEFVQDNHSRSAKGVL
CEEEEEECCCCCEEEECCEEECCCCCEEEECCCHHHHHHHHCCCCEEEECCCCCHHHHHH
RGLHYQIEHTQGKLVRVVEGEVFDVAVDVRRSSPNFGKWVGVTLSADNHRQLWVPPGFAH
HHHEEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCC
GFLVVSESAQFLYKTTDYWFPEHERSIVWNDPDIGIVWPLDGEPLLAVKDAAGMRLMDAD
EEEEEECCCEEEEEECCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEECCCCCEEECCC
LFE
CCC
>Mature Secondary Structure 
AIHVTATALPEVKLIEPKVFGDARGYFYESFNAREFAEHVAPGIEFVQDNHSRSAKGVL
EEEEEECCCCCEEEECCEEECCCCCEEEECCCHHHHHHHHCCCCEEEECCCCCHHHHHH
RGLHYQIEHTQGKLVRVVEGEVFDVAVDVRRSSPNFGKWVGVTLSADNHRQLWVPPGFAH
HHHEEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCC
GFLVVSESAQFLYKTTDYWFPEHERSIVWNDPDIGIVWPLDGEPLLAVKDAAGMRLMDAD
EEEEEECCCEEEEEECCCCCCCCCCEEEECCCCEEEEEECCCCCEEEEECCCCCEEECCC
LFE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]