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The map label for this gene is oprN7 [H]

Identifier: 78048207

GI number: 78048207

Start: 2986087

End: 2987577

Strand: Reverse

Name: oprN7 [H]

Synonym: XCV2651

Alternate gene names: 78048207

Gene position: 2987577-2986087 (Counterclockwise)

Preceding gene: 78048208

Following gene: 78048206

Centisome position: 57.69

GC content: 69.68

Gene sequence:

>1491_bases
ATGCGCCTGATCCGCATGCCGCTGGCTGCGGCGTTGGGCACGCTGCTGCTTGGCGGCTGCATGCTCGGCCCCAACTACAC
CAAGCCGCCAGCGGTTGCCGACGCGGCGATGCAGGCACCCGCCCTGCATCGTGCCAGCGGCGCAGACGTGGTCGCCGCCG
CACCGCTGAACCATTGGTGGGAGGAATTGCACGACCCGCTCCTGACCCAGTTGGTCACCCAGGCCTTGGCCGACAGCCCC
AACCTGCGCGCGGCACAGGCGCGGCTGCGTGCCAACCGCGCGCTGGCCCAGCAACGCCGCGCCGAGCGCCTGCCCAAGCT
CAACGCCAGCGCACTGTATGCCTACGCCGAACCGCCGCAGACCATTGTCGACACGCTCGGCGGGCTGCAACAGGGTCAAC
CCGGCCAGCCGCCGGCGGCCGGCAACCAGGCGCTGAACCTGGAAGAGACGCAGATCTACAGCGCCGGCTTCGATGCGAGC
TGGGAGCTGGATTTCTTCGGCCGCCGCCGTCGCGCCGCCGAAGGCGCGCTGGCGCAGGCACAGGCCTCCGAAGCCGAGCT
GGCCGATGCGCAGGTGCAGCTGGCCGCCGAAGTCGGGCAGGTCTATCTCAATTACCGCGGCTTGCAGGCGCGCCTGGCCA
TTGCCGATACCAACCTGGACAAGATCCGCCAGTCGCTGCAGCTGGTGCAGCAACGTCGCGGGCAGGGCGCCGCCTCGGAC
CTGCAGGTCGAGCAGATCGCCACCCAGGTGCAGCAGCAGGAGGCGCAACGCCTGCCGCTGGAAATGCAGGCGCAGGAAGC
GCAGGACCAGCTGGCCCTGATGGTCGGGCGCGAGCCCGGCGCGCTGGATGCCCAGCTCGGCACGCCGCAGCCCTTGCCGA
TGCTGCCGACACAGGTGCGCGTGGACGATGCCGGTGCGTTGATCCGCCGGCGCCCGGACGTGCGCAAGGCCGAGCGCGAG
CTGGCCGCCTCCAGCGCGCAGATCGGCGAGGCGTTGAACGGCTACTTCCCGCAGGTGAGTCTGCTGGGCGGGCTGAGCTG
GGTCGCCGGCTCGCCAAGCGATTTCAATTCCGACGCGCTGACCACATTGGCGGTGCCGATGCTGCGCTGGTCGATCTTCG
ATTTCGGCAAGACCCGCGCGCAGGTGGAGCAGGCACGTGCCGGTAATGCCGGGCGTACGGCAGCGTACGAAGGGAGCGTG
CTGGCTGCCTTGCAGGATGCCAATTCGGCGTTGGCGCGCTTCGGTTCGGCACGCAAGCAGCTGATGGTCGCACGCCAGGC
CGAAGCCTCGGCCACGCGCTCGGCCGGGCTGATGCAGCAGCGTCGCGATGCCGGTGCCACCTCATCGATCGATCTGCTGG
ATGTGCAGCGCCAGCAGTTGTCGGCGCAGGACGCTGCCGCACAGGCGCAGGTGCAGTTGCTGGTGAATTACGTGGCCCTG
CAGAAGAGTCTGGGGCTGGGCTGGAGCGCACCGGCGCAGGACGCGCACTGA

Upstream 100 bases:

>100_bases
CTGTTCTGGATCTTTGGCGTGATCGTGGTCTGCACGATTCCGCTGGCCTTTTTGCTCAAGCCGTTACCCAAGGGGGCGCA
CCTTGCAATGCACTGATTCC

Downstream 100 bases:

>100_bases
GAGCAGCCAGGGCAATCTGTGACGCGGCAGCCCATGCGCGGCCGCGTCCGGGTTTTGCCATCATGGTCGGCATTGGCCGT
TGTGGCGCATGCAATGCGCA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MRLIRMPLAAALGTLLLGGCMLGPNYTKPPAVADAAMQAPALHRASGADVVAAAPLNHWWEELHDPLLTQLVTQALADSP
NLRAAQARLRANRALAQQRRAERLPKLNASALYAYAEPPQTIVDTLGGLQQGQPGQPPAAGNQALNLEETQIYSAGFDAS
WELDFFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADTNLDKIRQSLQLVQQRRGQGAASD
LQVEQIATQVQQQEAQRLPLEMQAQEAQDQLALMVGREPGALDAQLGTPQPLPMLPTQVRVDDAGALIRRRPDVRKAERE
LAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDALTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTAAYEGSV
LAALQDANSALARFGSARKQLMVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLLVNYVAL
QKSLGLGWSAPAQDAH

Sequences:

>Translated_496_residues
MRLIRMPLAAALGTLLLGGCMLGPNYTKPPAVADAAMQAPALHRASGADVVAAAPLNHWWEELHDPLLTQLVTQALADSP
NLRAAQARLRANRALAQQRRAERLPKLNASALYAYAEPPQTIVDTLGGLQQGQPGQPPAAGNQALNLEETQIYSAGFDAS
WELDFFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADTNLDKIRQSLQLVQQRRGQGAASD
LQVEQIATQVQQQEAQRLPLEMQAQEAQDQLALMVGREPGALDAQLGTPQPLPMLPTQVRVDDAGALIRRRPDVRKAERE
LAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDALTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTAAYEGSV
LAALQDANSALARFGSARKQLMVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLLVNYVAL
QKSLGLGWSAPAQDAH
>Mature_496_residues
MRLIRMPLAAALGTLLLGGCMLGPNYTKPPAVADAAMQAPALHRASGADVVAAAPLNHWWEELHDPLLTQLVTQALADSP
NLRAAQARLRANRALAQQRRAERLPKLNASALYAYAEPPQTIVDTLGGLQQGQPGQPPAAGNQALNLEETQIYSAGFDAS
WELDFFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADTNLDKIRQSLQLVQQRRGQGAASD
LQVEQIATQVQQQEAQRLPLEMQAQEAQDQLALMVGREPGALDAQLGTPQPLPMLPTQVRVDDAGALIRRRPDVRKAERE
LAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDALTTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTAAYEGSV
LAALQDANSALARFGSARKQLMVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLLVNYVAL
QKSLGLGWSAPAQDAH

Specific function: The outer membrane component of an organic solvent efflux pump. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been po

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=493, Percent_Identity=25.9634888438134, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI2367348, Length=501, Percent_Identity=24.5508982035928, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53052; Mature: 53052

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIRMPLAAALGTLLLGGCMLGPNYTKPPAVADAAMQAPALHRASGADVVAAAPLNHWW
CCEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHCCCCCCEEEECHHHHHH
EELHDPLLTQLVTQALADSPNLRAAQARLRANRALAQQRRAERLPKLNASALYAYAEPPQ
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHH
TIVDTLGGLQQGQPGQPPAAGNQALNLEETQIYSAGFDASWELDFFGRRRRAAEGALAQA
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHH
QASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADTNLDKIRQSLQLVQQRRGQGAASD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCHH
LQVEQIATQVQQQEAQRLPLEMQAQEAQDQLALMVGREPGALDAQLGTPQPLPMLPTQVR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
VDDAGALIRRRPDVRKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDAL
ECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHCCCCCCCCCHHH
TTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTAAYEGSVLAALQDANSALARFGSARKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
LMVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLLVNYVAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSLGLGWSAPAQDAH
HHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRLIRMPLAAALGTLLLGGCMLGPNYTKPPAVADAAMQAPALHRASGADVVAAAPLNHWW
CCEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHCCCCCCEEEECHHHHHH
EELHDPLLTQLVTQALADSPNLRAAQARLRANRALAQQRRAERLPKLNASALYAYAEPPQ
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHH
TIVDTLGGLQQGQPGQPPAAGNQALNLEETQIYSAGFDASWELDFFGRRRRAAEGALAQA
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCEEHHHHHHHHHHHHHHHHHH
QASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADTNLDKIRQSLQLVQQRRGQGAASD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCHH
LQVEQIATQVQQQEAQRLPLEMQAQEAQDQLALMVGREPGALDAQLGTPQPLPMLPTQVR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
VDDAGALIRRRPDVRKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDAL
ECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHCCCCCCCCCHHH
TTLAVPMLRWSIFDFGKTRAQVEQARAGNAGRTAAYEGSVLAALQDANSALARFGSARKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
LMVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLLVNYVAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSLGLGWSAPAQDAH
HHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9417051; 9852029 [H]